Emerging Methods

[ZeuterMe (imported)]

Inspired by the Texas Cowboy, I wanted to make a thread here cataloguing the emerging approaches to sterilization, and encourage anyone who is interested in experimenting to discuss their approaches to finding access to them, and results once they have done so, in a convenient and central location.

For starters, a list composed by the Parsemus foundation for male dogs:

Zeuterin™ - Zinc gluconate in arginine, compounded with dimethylsulfoxide for reduction of inflammation and increased diffusion through tissue (DMSO is famously tissue permeating, and can cause contact poisoning when mixed with other chemicals). This is in fact what I was searching for information on when I found the Archives, and chose my name in a fit of pique.

Epididymal injection of Calchlorin - A refinement of the EA calcium chloride protocol emphasizing sterilization first, hormones second. JCat has noodled with this, but his preexisting conditions make it hard to extrapolate from his case study.

Epididymal injection of sotradecol - Sotradecol is the sclerosing drug used to plug spider veins; injecting it into the epididymus causes it to be plugged with scar tissue.

Epididymal ligation - Derived from the pinhole castration technique developed by Ponvijay and described in 2007's "Veterinary Surgery" journal, this is a pinhole vasectomy. It requires a 10 cm length of suture material, an 18-ga needle, and no aftercare.

Ultrasound - Can be used to disrupt sperm-forming tissues somewhat reversibly, or to seal the epididymus or vas with a scar plug by cooking a tiny piece of tissue (though targeting the epididymus is significantly easier and more successful).

Vasalgel - Claimed to be good for ten years at a time, this injection of strongly charged polymer into the vas destroys sperm passing through the region, leaving a man shooting blanks. It can be washed out of the vas at any time by the injection of a DMSO based solvent to remove it, restoring full fertility immediately.

Radio Control Implant - A plug that can be toggled between open and closed with a radio fob like a remote keyless entry on a late-model car is injected into the vas. You can toggle fertility between on and off at will, with only a few days of lag time before your choice is fully expressed.

Heating - I read a protocol here on the Archive for temporary, reversible castration with reusable chemical heat packs, and I've read work done on clinical trials of the same approach. This should be one of the cheapest, least-invasive approaches here.

And finally, while not something I've ever read about, has anybody else got any information on testicle transplants? Bonus points on xenotransplants, because the idea of fathering a litter of puppies amuses me in a surreal sort of way at this hour.

[jcat (imported)]

Great idea this thread. I have realized people are very conservative and stick to what they know. I am very keen to find out more about cord injections and I will update the results of my medical scans coming up....

Hipefully someone brave will step up and try what I can't now do.

[micdavi24 (imported)]

There is one method that I remember reading about in the late 70's or early 80's where a small 3 way tap was installed in the vas during a vasectomy. This tap allowed it to be turned either to allow the passage of sperm to the prostate for ejaculation or to discharge harmlessly into the scrotum. Does anyone remember this and whether it was ever used in actually surgeries

[artisticlicense (imported)]

Excellent 'how-to' video at spayfirst.org (http://www.spayfirst.org/programs/non-s ... ilization/) for the use of Calcium Chloride (Calchlorin (http://www.calchlorin.org/)) injections. Compilation/formulation, weight and dosing instructions, tools & types of syringes needed, to proper injection procedure and aftercare.

Printed PDF version here (http://www.spayfirst.org/wp-content/upl ... nglish.pdf).

Clinical reports here (http://www.spayfirst.org/wp-content/upl ... .2.119.pdf) and here (http://www.actavetscand.com/content/56/1/62).

[ZeuterMe (imported)]

Pinhole Castration / "Vasectomy": Performed in 60-90 seconds per side, the entire sperm cord or the epididymus can be ligated subdermally with the only wound a 18-ga needle stick. If the entire sperm cord is ligated, the result is similar to a burdizzo castration or testicular torsion - the blood supply is disrupted, and nature takes its course. If the epididymus is ligated lower, bypassing the testicular artery, the compression leads to scarification of the seminal vesicles and sterility without castration. First described back in 2007, in the Journal of Veterinary Surgery volume 36, pages 74–79, this approach has been tested in dogs ( [url=http://s3.amazonaws.com/academia.edu.do ... -libre.pdf), rams, and bulls. While the original paper is paywalled, other papers providing a description and discussing alterations to the process have been published in open-access journals (or articles leaked online ( [url=http://s3.amazonaws.com/academia.edu.do ... _Technique _for_Preparation_of_Teaser_Rams-libre.pdf)).

This one might, if resorbable sutures are used, be forensically identical to torsion - in the dog study, they couldn't even find the needle sticks the day after they worked on the experimental group.

[ZeuterMe (imported)]

The cartridge idea is pretty interesting, though I'm not sure how you'd empty them if they were implanted. Are you talking about a transdermal implant?

Right now, I'm here to pass along something I found accidentally - a nifty new surgical approach that combines the benefits of open and closed castrations. This doesn't seem to be the conventional "semi-closed" approach, either. http://www.ncbi.nlm.nih.gov/pubmed/24063115

Also new to this forum to the best of my ability to tell is the "double subcutaneous torsion" approach. Requiring only good manual dexterity and a bit of string, perhaps a twist-tie or a loose rubber band, this one should be forensically identical to a natural torsion, since it relies upon creating one and securing it in a twisted position for a day or two. The results should be obvious.

https://archive.org/stream/animalcastra ... 8/mode/2up

[daifu-orchid (imported)]

Twisting would seem to be similar to an elastrator or a callicrate? Both safely effective in animals, but I suspect too uncomfortable for people.

[ZeuterMe (imported)]

Twisting would seem to be similar to an elastrator or a callicrate? Both safely effective in animals, but I suspect too uncomfortable for people.

Uncomfortable, but not agonizing. The biggest problem is the method of securing them in the twisted position simply doesn't work in humans, especially if yours can retract up into the inguinal canal. I suspect securing them in the bottom of the sac with a broccoli band might be a more productive approach.

I won't try any kind of long-term test fitting, however, since I've got problems enough already, and I'd rather not make them worse.

“Acute ischemia through torsion or ligation of spermatic cords for as little as 5 hours,

followed by reperfusion, causes irreversible loss of spermatogenesis”

“In rats, a 5h reduction in flow to approximately 70% of the normal value may be sufficient to induce death among spermatogonia and early primary spermatocytes. High-grade ischemia causes necrotic damage to all parts of the testis.” (Bergh et al., 2001)

Bergh A, Collin O and Lisbrant E (2001).

Effects of acute graded reduction in

testicular blood flow on testicular

morphology in the adult rat. Biology of

Reproduction, 64: 13

[ZeuterMe (imported)]

Zeuterme,

Do you have that video link? I'd be interested to see it done. Thanks in advance.

Nutme248

DuckDuckGo delivers: http://bobweekend.com/neuter_web/

[nvrgag44 (imported)]

DuckDuckGo delivers: http://bobweekend.com/neuter_web/

Wow! Those pics sure look like the real deal, don't appear photo shopped. A scrotum that large seems like it would always be in the way. The finished product looks like it would restrict normal movement and be pretty uncomfortable. I personally think if I ever found myself in the position of badly wanting or needing castration and going through with it I would definitely go in the opposite direction and have my scrotum also removed, preferably by a skilled surgeon who can make it look like there was never a scrotum there. From the many pictures I've seen (assuming they weren't photo shopped) it looks very natural and eye appealing when done right.