Emerging Methods
Posted: Mon Dec 08, 2014 4:10 am
Inspired by the Texas Cowboy, I wanted to make a thread here cataloguing the emerging approaches to sterilization, and encourage anyone who is interested in experimenting to discuss their approaches to finding access to them, and results once they have done so, in a convenient and central location.
For starters, a list composed by the Parsemus foundation for male dogs:
Zeuterin - Zinc gluconate in arginine, compounded with dimethylsulfoxide for reduction of inflammation and increased diffusion through tissue (DMSO is famously tissue permeating, and can cause contact poisoning when mixed with other chemicals). This is in fact what I was searching for information on when I found the Archives, and chose my name in a fit of pique.
Epididymal injection of Calchlorin - A refinement of the EA calcium chloride protocol emphasizing sterilization first, hormones second. JCat has noodled with this, but his preexisting conditions make it hard to extrapolate from his case study.
Epididymal injection of sotradecol - Sotradecol is the sclerosing drug used to plug spider veins; injecting it into the epididymus causes it to be plugged with scar tissue.
Epididymal ligation - Derived from the pinhole castration technique developed by Ponvijay and described in 2007's "Veterinary Surgery" journal, this is a pinhole vasectomy. It requires a 10 cm length of suture material, an 18-ga needle, and no aftercare.
Ultrasound - Can be used to disrupt sperm-forming tissues somewhat reversibly, or to seal the epididymus or vas with a scar plug by cooking a tiny piece of tissue (though targeting the epididymus is significantly easier and more successful).
Vasalgel - Claimed to be good for ten years at a time, this injection of strongly charged polymer into the vas destroys sperm passing through the region, leaving a man shooting blanks. It can be washed out of the vas at any time by the injection of a DMSO based solvent to remove it, restoring full fertility immediately.
Radio Control Implant - A plug that can be toggled between open and closed with a radio fob like a remote keyless entry on a late-model car is injected into the vas. You can toggle fertility between on and off at will, with only a few days of lag time before your choice is fully expressed.
Heating - I read a protocol here on the Archive for temporary, reversible castration with reusable chemical heat packs, and I've read work done on clinical trials of the same approach. This should be one of the cheapest, least-invasive approaches here.
And finally, while not something I've ever read about, has anybody else got any information on testicle transplants? Bonus points on xenotransplants, because the idea of fathering a litter of puppies amuses me in a surreal sort of way at this hour.
For starters, a list composed by the Parsemus foundation for male dogs:
Zeuterin - Zinc gluconate in arginine, compounded with dimethylsulfoxide for reduction of inflammation and increased diffusion through tissue (DMSO is famously tissue permeating, and can cause contact poisoning when mixed with other chemicals). This is in fact what I was searching for information on when I found the Archives, and chose my name in a fit of pique.
Epididymal injection of Calchlorin - A refinement of the EA calcium chloride protocol emphasizing sterilization first, hormones second. JCat has noodled with this, but his preexisting conditions make it hard to extrapolate from his case study.
Epididymal injection of sotradecol - Sotradecol is the sclerosing drug used to plug spider veins; injecting it into the epididymus causes it to be plugged with scar tissue.
Epididymal ligation - Derived from the pinhole castration technique developed by Ponvijay and described in 2007's "Veterinary Surgery" journal, this is a pinhole vasectomy. It requires a 10 cm length of suture material, an 18-ga needle, and no aftercare.
Ultrasound - Can be used to disrupt sperm-forming tissues somewhat reversibly, or to seal the epididymus or vas with a scar plug by cooking a tiny piece of tissue (though targeting the epididymus is significantly easier and more successful).
Vasalgel - Claimed to be good for ten years at a time, this injection of strongly charged polymer into the vas destroys sperm passing through the region, leaving a man shooting blanks. It can be washed out of the vas at any time by the injection of a DMSO based solvent to remove it, restoring full fertility immediately.
Radio Control Implant - A plug that can be toggled between open and closed with a radio fob like a remote keyless entry on a late-model car is injected into the vas. You can toggle fertility between on and off at will, with only a few days of lag time before your choice is fully expressed.
Heating - I read a protocol here on the Archive for temporary, reversible castration with reusable chemical heat packs, and I've read work done on clinical trials of the same approach. This should be one of the cheapest, least-invasive approaches here.
And finally, while not something I've ever read about, has anybody else got any information on testicle transplants? Bonus points on xenotransplants, because the idea of fathering a litter of puppies amuses me in a surreal sort of way at this hour.