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Castration for a post-cancer sub
Posted: Wed Nov 10, 2010 12:59 am
by Fait Accompli (imported)
I am looking for some advice on what is obviously a very complicated subject. I am a very serious and experienced sub who has recently had a (looking succesful) Radical Prostatectomy because of Prostate Cancer. I am now left with difficulty gaining an erection etc without Edex or Caverjet injections. My rare orgasms are also obviously dry.
I have done lots of severe S & M stuff, am a lifestyle sub and have long spoken with my long-term Mistress about castration anyway. She rarely lets me be satisfied and I spend the bulk of the time in chastity so all this seems like a bit of a fait accompli given my illness and after effects. She firmly believes that castration is the ultimate way to really own a male slave
My partner (Mistress) keeps me totally hair-free and also has long wanted me to have small breasts. She has a very definite preference for surgical castration but is keen to experiment with chemical castration first to get things started as soon as possible.
We are both free of commitments (apart from me to her of course) and this has been a very real desire for a number of years. I am ready to make the ultimate sacrifice and My Mistress would therefore appreciate any sound advice anyone can give in helping us take this to the next stage.
Many Thanks
Re: Castration for a post-cancer sub
Posted: Wed Nov 10, 2010 5:48 am
by clysmaniac (imported)
My best friend has prostate cancer. He has had his prostate removed and chemo. He complains that he gets horny but can't get erect to do anything about it with his wife. Both of them know I am castrated and the side effects that go along with that. But both also think he would be better off being castrated as well to eliminate him being horny and without the ability for a release. He could always take small amounts of testosterone as needed for bone health and strength but not enough to turn on his libido again. In your case estrogen would work and is less hassle to get than T. His doctors don't seem to think that is a medical necessity and have been slow to do the procedure but then I don't really know how they have pushed to have him castrated.
So you are not alone in looking at castration in your situation.
Re: Castration for a post-cancer sub
Posted: Wed Nov 10, 2010 6:40 am
by Fait Accompli (imported)
Thanks for the reply Clysmaniac. This is just a difficult thing to start out alone. I have trawled through here a lot but there are just so many different answers and threads. We both wnat to get this going as soon as possible to be honest. Mistress has no interest in my bits anyway and loves the idea of me having little or no sex drive although she does wonder if she can still make my cock hard with the Caverjet injections once castration has taken place?
I see there are online pharmacies. Is there a specific Estrogen that we should buy? What about doseage and how long does it take before things start to happen. M loves the idea of messing with my mind anyway so I guess she will enjoy that. Personally I just feel safe and secure with her (strange eh!) so will just go with the flow.
Have you any ideas how long chemichal castration might take? What about removal after as I know that will be a definite priority at some stage in the near future. Is that just a nightmare to get done safely?
Lastly, any ideas on the breast request. Thanks ever so much for your help....
Re: Castration for a post-cancer sub
Posted: Wed Nov 10, 2010 6:43 am
by Milkman (imported)
First thing is that I am glad to know that your cancer operation was a success and that you are still alive!! You seem to have a good attitude to turn this misfortune into part of your imaginative and seemingly enjoyable sex life!!
Re: Castration for a post-cancer sub
Posted: Wed Nov 10, 2010 6:58 am
by Fait Accompli (imported)
Thanks Milkman. It was a scarey old time but I have agreat partner who understands me and whom I love very much. I was not actually even ill (touch wood) from the cancer. It was just found. Aggresive and no choice but removal but luckily caught in time. Given M's desires it does all rather seem like a whole binch of fate though!
Re: Castration for a post-cancer sub
Posted: Wed Nov 10, 2010 7:09 am
by mrt (imported)
Fait Accompli (imported) wrote: Wed Nov 10, 2010 12:59 am
I am looking for some advice on what is obviously a very complicated subject. I am a very serious and experienced sub who has recently had a (looking succesful) Radical Prostatectomy because of Prostate Cancer. I am now left with difficulty gaining an erection etc without Edex or Caverjet injections. My rare orgasms are also obviously dry.
I have done lots of severe S & M stuff, am a lifestyle sub and have long spoken with my long-term Mistress about castration anyway. She rarely lets me be satisfied and I spend the bulk of the time in chastity so all this seems like a bit of a fait accompli given my illness and after effects. She firmly believes that castration is the ultimate way to really own a male slave
My partner (Mistress) keeps me totally hair-free and also has long wanted me to have small breasts. She has a very definite preference for surgical castration but is keen to experiment with chemical castration first to get things started as soon as possible.
We are both free of commitments (apart from me to her of course) and this has been a very real desire for a number of years. I am ready to make the ultimate sacrifice and My Mistress would therefore appreciate any sound advice anyone can give in helping us take this to the next stage.
Many Thanks
Its just an opinion but your interests in sex whatever it is would be just about zero post castration. So, if she is wanting you to be "interested" I think that would be pretty well shut down. Chastity for example takes a person who has needs and used that to focus attention on his partner. If you remove that? You may find you don't care about the game. You really ought to talk to some people who can explain just how much testosterone drives a person and NOT just for sex btw. Mood, energy, mental clarity etc. Its a pretty serious thing to fiddle with for a kink...
Re: Castration for a post-cancer sub
Posted: Wed Nov 10, 2010 7:27 am
by Caith721 (imported)
As milkman said, first and most importantly, congratulations on surviving and excising the cancer very early. Second, here are four steps to chemical castration and feminization for you:
InHouse Pharmacy online (
http://www.inhousepharmacy.biz/transgen ... ender.html) They are a very reliable source for genuine quality pharmaceuticals.
50mg Siterone (
http://www.inhousepharmacy.biz/transgen ... erone.html) (cyproterone acetate), taken twice per day. This is the anti-androgen. Start this a week or two before estrogen to reduce your testosterone levels.
2mg Estrofem (
http://www.inhousepharmacy.biz/transgen ... fem-t.html)(17-beta estradiol) taken once daily beneath your tongue until dissolved. It's pleasant, and almost sweet. After the first week (or two) at 2mg, increase to twice daily for a total of 4 mg. After two to four weeks, increase to two tablets in the morning and two in the evening. This is a total of 8 mg and the most you should attempt to consume. Any higher levels are not productive, and could be counter-productive or even dangerous. After several weeks, you should begin to feel small firm lumps growing beneath your nipples. These are your breasts beginning to bud.
Last, but also most importantly, have your doctor regularly perform blood tests to monitor your lipids and liver enzymes as you begin. Both Siterone and Estrofem affect your endocrine system, and you should at least have a doctor (endocrinologist if possible) monitoring your progress.
Good luck, and may you and your Mistress both be extremely pleased with the results.

Re: Castration for a post-cancer sub
Posted: Wed Nov 10, 2010 7:46 am
by Fait Accompli (imported)
Firstly Mr T, thanks for the words of warning. This is something we have discussed for a long period of time and the issues with my cancer mean that sex is a major issue anyway plus I have enough trust in our (very long) relationship to be comfortable when M goes elsewhere for her sexual pleasure. As an aside, she prefers young athletic guys and I am happy for her to be happy. I have also for a long time made satisfying her a priority so there will not be much change in castration anyway! Thanks again for the words though..
Moving on to Caith. Thanks ever so much for the positive directions. Can I throw a few more questions at you please? Is it OK to do it here or should I mail you direct. I guess this could be interesting/beneficial to others so I am fine to go publice if you are!
Do the two drugs you recommend form perform the castration and breast development ar are they seperate? Is there a name for the Estrogen drug as well? Is this something you have been through and if so are there any wise words on time-frames, side effects etc.
Also what about removal after chemical castration. Will there be any physical change in my balls once I start the Estrogen etc.
Thanks so much for the advice x
Re: Castration for a post-cancer sub
Posted: Wed Nov 10, 2010 10:58 am
by butterflyjack (imported)
Hi fait accompli....and thanks for the feminizing advice Caith...
I was browsing through the feminization section of Inhouse Pharmacy last night..I saw a mention of a 21 day cycle birth control program that looked interesting . I forget the name....something35...a generic version of another 35 something drug....It's a comdo of mild androgen and mild estrogen...It seemed a little light though, for someone attempting to feminize with testosterone still coursing through his veins from his intact testes.. Your regimen sounds better..
I'm really tempted to try this...I am presently taking Avodart for benign prostrate syndrome...I wonder if this would have any effect on this and my being able to urinate? I'm thinking that this might eliminate the need for the Avodart and relieve the benign prostrate problem, through the elimination of the T (which I assume is the problem, anyway)...What might be anyone's thoughts on this issue? Thanks dragonfly
Re: Castration for a post-cancer sub
Posted: Wed Nov 10, 2010 1:41 pm
by Caith721 (imported)
Diane35 is a combination of ethinyl estradiol (a very potent estrogen) and a very low dose of cyproterone acetate. The issues with Diane35 is the ethinyl component can cause DVT (deep vein thrombosis, blood clots) and stroke, and is strongly NOT advised for men over 50, especially those who smoke.
Of the other two named drugs:
Siterone is a generic version of cyproterone acetate, a powerful anti-androgen. This drug will drop your testosterone levels and lower the frequency and occurence of spontaneous erections.
Estrofem is a trademarked version of 17-beta estradiol, a bio-identical form of estrogen prepared from soy compounds. This hormone is what generates breast tissue, causes skin layers to become thinner, and causes sebum/oil production to decrease, resulting in smaller pores. Depending on your individual body chemistry, you may or may not experience fat redistribution to your hips and/or tummy.
All the knowledge I have, I gained from the Yahoo! group TSDoItYourselfHormones, reading and reading the messages for a period of years. Some of the best advice they have is to start the anti-androgen first, by itself. That allows you to determine your body's reaction to it BEFORE you start to add in the estrogen. If you experience any problems taking the anti-androgen for the first two weeks, you should definitely get blood tests performed immediately. If not, you can happily move on to adding the estrogen and slowly ramping up your dosage. Too much estrogen too soon is NOT GOOD for your liver. Give your body time to adjust to the changes and settle in before increasing or adding any other drugs.
Finally, it is always STRONGLY ADVISED to get blood tests performed regularly, especially when you are starting out. Any time you self-medicate, 100% of the responsibility for any medical issues you experience becomes your own. You cannot hold your doctor or the drug companies responsible when doing this. It's your decision, your actions, and your responsibility.
FYI, I've recently switched from spironolactone/aldactone to cyproterone acetate, and I'm taking a generic form of 17-beta estradiol manufactured by Barr Laboratories. Over the last two years, it's grown small B-cup breasts on my 53-year old 6'2" frame.

I'm fortunate to have a doctor who is trans-friendly and provides my estrogen prescription and performs regular blood tests.