Does anyone know anything about Chem-Cast? I understand that it is a lactic acid based injectable castration agent. (Neutersol is zinc arginine based.) I am wondering how it compares to Neutersol in effectiveness. Also, of course, does anyone know whether it is effective on humans?

I know there has been discussion on some of the fora regarding lactic acid injection but I had not realized that there was a commercial product with that as the active agent.

Bill

I just posted on Chem-Cast on the "Eunuchs in the Arts and News" board a few days ago ...

The difference seems to be that Chem-Cast fully castrates (testicles are destroyed), whereas with Neutersol it seems to mostly affect sperm production. So it seems it may be the difference between castration and sterilization.

In any case, see my other posting for a number of links on both chemicals.

I wish I could find more specific information on Chem-Cast. It doesn't seem to be widely available, but would definitely like to try it. If it is just lactic acid, I wonder if that could be injected to the same effect?

Here is what one page says about the effect of Chem-Cast :

"Chemical castration- Chem-cast, approved by FDA in 1983, as a painless way to destroy testicles and spermatic cords of bull calves weilghing up to 150 lbs. There is no weight loss, off feed, high risk of infection, hemorrhaging or pain. It is 100 % effective. The procedure consists of injecting chem-cast ( 1 ml per testicle for calves weighing 100 lbs ) from top into middle third of testicle via small hypodermic needle. Swelling of the testicle occurs after 24 hours of injection. The swelling disappears in 2 weeks and testicle is reabsorbed and reduced in size. At 60 days, testicles are small, hard nodules and these disappear."

Sounds effective!

hey guys,

this chem cast sounds great where can i get mine?

has any one got personal experience with it?

can i get it from vet is it safe ?

is it expensive?

i am ready for this

Where does one get this?

there is not a lot on the web on this for a vet product out there since 1984. sounds good for what many of us are looking for. i saw some months ago a posting from a fellow who was going to inject himself with lactic acid. incidently the cost of the med per calf is $2.00. lactic acid is cheap and should be readily available. like others i would like to learn of anybody's experinece.

I have researched Chem-Cast more, and the company that made it removed it from the FDA approval process. I am not sure why.

I agree that lactic acid is reasonably well available. Specifically, Chem-Cast used "DL-lactic acid". However, I think it is important to know the concentration of acid used, which is impossible since the company wouldn't publish that (probably a trade secret).

Apparently a 9% solution of DL-lactic acis is quite acidic (pH of 2.9) so I don't think you'd want to use a solution an more concentrated than that.

My biggest hope for permanent chemical castration is the drug being developed by Gonex. See www.gonex.com

lactic acid itself is acidic but it might have been given as a salt. both the D.L and the resolved forms are readily available. lactic acid and its salts are present in lots of food stuffs and is a natural component of living things.

the gonex product appears to be a sterilant rather than an agent for castration.

No, the Gonex product is an anti-androgen as well, because it will be marketed for cancer therapy in humans.

If Gonex works with only one injection then it must be a permanent castrating agent. Also, though tempting, injecting anything directly into the testis would be very painful. Has anyone ever done that?

No, injections into the testicles are not very painful.

I've done it regularly, and injected everything from saline to cooking oil to hormones. Assuming you have a good, sharp hypodermic needle and insert slowly, there is little to no pain. I have injected up to six CCs at a time. There was no pain during or afterwards, and no significant bleeding (occasionally one small drop).

Additionally, specifically with the lactic acid of Chem-Cast, it says that there is little pain (for animals) because lactic acid is used within the body to numb sore muscles.