I've been chemically castrated since march 2018 and never felt better. Until a couple months ago that is.

My blood test from last week shows abnormal levels, my testosterone has risen five fold up to about 100pg/ml! Before it was at a stable 20pg/ml.

Also my junk has started to hurt even more often now, and it's getting unbearable.

I don't know what to do now. My endo doesn't know what might have caused this. Technically my estrogen levels alone are enough to bring me to castrate levels but I've been taking Androcur as well just to be sure.

It worked really well before but suddenly no longer.

My endo raised my Androcur dose to 50mg now and I've started taking 500mg Flutamide on the side.

No one seems to know what is going on and no one is able to help me. I'm still kind of reluctant to physically castrate myself, considering the pain and risks and all.

But I really don't want to detransition. I'm so fucking scared!

Mabe you should look at a DHT blocker to make sure none of the T is converted to DHT which is far more powerful. You may also want to look at the CaCl Injections so that you can be rid of anti androgens which are hard on your mental and physical health. Good luck!

I doubt that finasteride would be any help at this point. Or anything really.

My T won't go down anymore and it's having a devastating effect. If HRT really doesn't work anymore then I should probably just kill myself.

I've been told a noose is rather quick and painless, but I haven't decided yet.

Calcium Chloride to kill them and your T WILL go down for sure!

You were on a very low dose of CA so I wouldn't conclude that CA won't suppress your T. You may want to go up to 250mg a day for 10 days then start reducing dosage from there. If it's upsetting enough to contemplate suicide, you should seriously consider killing your nuts for good rather than yourself.

Forget about Finasteride, it won't lower your testosterone, only DHT.

You should ask for Lupron and an other gnrh agonist/antagonist.

CPA is dangerous is a long term run (meningioma). Flutamide won't lower your testosterone, at least its not supposed to work that way. It just compete for binding to the androgen receptors (like Bicalutamide, Enzalutamide, Darolutamide), it doesn't lower testosterone level (except if you take estradiol with it).

JessicaH (imported) wrote: Tue Aug 13, 2019 4:09 am You were on a very low dose of CA so I wouldn't conclude that CA won't suppress your T. You may want to go up to 250mg a day for 10 days then start reducing dosage from there. If it's upsetting enough to contemplate suicide, you should seriously consider killing your nuts for good rather than yourself.

I'm sorry, I didn't mean to upset anyone. Fighting against my own body is alre

norgefluid (imported) wrote: Wed Aug 14, 2019 3:04 pm ady pretty hard, and I feel like it's a losing battle.

Forget about Finasteride, it won't lower your testosterone, only DHT.

You should ask for Lupron and an other gnrh agonist/antagonist.

CPA is dangerous is a long term run (meningioma). Flutamide won't lower your testosterone, at least its not supposed to work that way. It just compete for binding to the androgen receptors (like Bicalutamide, Enzalutamide, Darolutamide), it doesn't lower te

stosterone level (except if you take estradiol with it).

Leuprorelin and Triptorelin are about €300 and €350 respectively, which goes way over my budget unfortunately. I also doubt my endo is even allowed to prescribe it.

People don't really care about the CPA risks because it's rare and it won't kill you. CPA is the de-facto standard here and I'd probably wouldn't be able to get anything else except maybe spiro because of the WPATH rulebook. And considering I probably already have a prolactinoma, my endo doesn't care.

Weird thing is, my estrogen is at > 700pg/ml which should have a very potent antigonadtropic effect.

My prolactin is at 150ng/ml which should also be enough to pretty much bring me to castrate levels on it's own.

And CPA tends to cap out at about 10mg when it comes to it's antigonadtropic effects, but I was already taking more.

My LH/FSH is bottomed out at the undetectable range, and my GP told me my nuts were "visually atrophied".

I'm basically stuffed to the brim on antigonadtropins so I'm left wondering if this T even comes from the gonads. It should be theoretically impossible.

If this is adrenal T then I'm pretty much screwed. Because then even surgical castration won't help, and the only things left to try would be AR antagonists (like Bicalutamide) or androgen synthesis inhibitor (like Abiraterone acetate).

Now the same effect is confirmed with me as well. I have been on 100mg/day of Androcur dosage since 1st of june. at the end of june T measured 17ng/dL. At the beginning of August I started to feel more horny and to masturbate much more often. From twice a month to twice a week it went. And now my T level measured 47ng/dL. Androcur is failing to work? Is it my liver that metabolizes Androcur much faster?

Sorry if this has been asked/answered. What is the source of the meds? If not doctor prescribed, could it be a case of a supplier sending medication that isn't legit or the right dosage?

Wolf-Pup (imported) wrote: Tue Aug 27, 2019 4:47 pm Sorry if this has been asked/answered. What is the source of the meds? If not doctor prescribed, could it be a case of a supplier sending medication that isn't legit or the right dosage?

That question is irrelevant at the moment, as all the meds I got - 5 month supply, are from the same source. Single order. Arrived in the same box. It is not possible that they work selectively in the time. Plus, I have more than one open boxes in different locations that I use when I am at these places, so I never forget to take them with me.