Anybody have experience using progestins? I'm most interested in natural progesterone but I'm really curious to know if anyone here has had any particularly negative or positive results with this stuff?

There is a big difference between natural progesterone and medroxy progesterone (Depot Provera). The first acts as a anti estrogen and might, as needed, transform into testosterone, the second will act as an anti testosterone. Keep in mind that castration might not eliminate all your sex drive but greatly reduce it.

progestins (synthetic) make me gain too much weight!!! I dont recommend synthetic ones

Thanks paring, thanks Frida.

Paring: I feel like I can handle a reduced sex drive--I don't think I have to kill it completely, though I wouldn't mind that. I've been with a therapist for several years & I think I can handle things as long as I can knock down the impulsiveness. My interest in progestins is to theoretically minimize muscle loss and hot flashing, and protect against osteoporosis. I didn't really think about how progesterone can become testosterone or progestin, whereas progestins are essentially stuck as progestin, and would therefore have a theoretically potent anti-libido effect that progesterone would not. I'll definitely keep that in mind.

Frida: My mom hated progestins--she hated progesterone, too but it was much more tolerable. I'm starting to watch my weight--its always been easy for me to get thin so now I have to learn to be careful!