Unresponsive to Cyproterone Acetate?
Posted: Tue Jun 12, 2018 5:09 pm
Long story short, I have gender dysphoria (MtN), have wanted my testicles gone since puberty, have had facial surgery, full body/face hair removal but no desire for breasts.
But I also suffer from extreme arousal. Was masturbating several times a day. Was on 25mg CA for 2 years, had little affect on arousal or erections. Experimented with higher doses, but made no difference.
I stoped CA 3 weeks prior to FFS, and didn't resume till a few months later due to medication complications (gallbladder).
During that time my arousal became much worse (constant state of orgasm).
Assumption was a result of spike in T from stopping CA.
I've since been on 50mg CA for last 4 months. I'm no longer in constant state of orgasm, but still get flares of extreme arousal which is very debilitating.
Total T went from 900ng/l to 380 after first 30 days, have had a CBC's since then but haven't had T retested yet. Assume near castration levels as ejaculation is non existent, nipples extremely sensitive, and what few body hair I had left disappeared.
Arousal is worse lying down, suggesting its not varicose vein, this also makes sleep impossible without pills.
I was prescribed Zoloft to help with the arousal, but couldn't tolerate it, caused painful erections and insomnia. Open to trying other SSRI's.
Has anyone experienced similar? Would orchiectomy solve what CA couldn't? From what I understand CA should be more effective then castration since it also blocks T from the adrenal glands.
To make this curse worse, about 6 months ago ejaculation started causing uretha pain and urinary urgency. I'm told T may help with this, but I can't increase my T without increasing my arousal. So I'm in a bind. Does E help with uretha pain and urgency?
I really feel I've ruined my body somehow, either from CA, or possibly cycling, or psychotropics and need some relief, I just can't deal with my genitals any more.
But I also suffer from extreme arousal. Was masturbating several times a day. Was on 25mg CA for 2 years, had little affect on arousal or erections. Experimented with higher doses, but made no difference.
I stoped CA 3 weeks prior to FFS, and didn't resume till a few months later due to medication complications (gallbladder).
During that time my arousal became much worse (constant state of orgasm).
Assumption was a result of spike in T from stopping CA.
I've since been on 50mg CA for last 4 months. I'm no longer in constant state of orgasm, but still get flares of extreme arousal which is very debilitating.
Total T went from 900ng/l to 380 after first 30 days, have had a CBC's since then but haven't had T retested yet. Assume near castration levels as ejaculation is non existent, nipples extremely sensitive, and what few body hair I had left disappeared.
Arousal is worse lying down, suggesting its not varicose vein, this also makes sleep impossible without pills.
I was prescribed Zoloft to help with the arousal, but couldn't tolerate it, caused painful erections and insomnia. Open to trying other SSRI's.
Has anyone experienced similar? Would orchiectomy solve what CA couldn't? From what I understand CA should be more effective then castration since it also blocks T from the adrenal glands.
To make this curse worse, about 6 months ago ejaculation started causing uretha pain and urinary urgency. I'm told T may help with this, but I can't increase my T without increasing my arousal. So I'm in a bind. Does E help with uretha pain and urgency?
I really feel I've ruined my body somehow, either from CA, or possibly cycling, or psychotropics and need some relief, I just can't deal with my genitals any more.