Okay, I don't know if anybody remembers that thread I made a few months back about bringing up the issue of castration to a doc and my dysphoria regarding my unwelcomed libido. Well, I never did actually see a doctor. After combing through the internet for answers on what to do the risk of approaching a doctor seemed like it might not be the best option, and they would not be receptive to my needs. Instead I've been kind of just browsing these forums and trying to decide what's best for me and if the risk seemed worth it. I talked to a few trans people with their personal experiences rolling the dice with hormones and how to deal with online pharmacies. I know it's a big risk to DIY but you see, I live in a small town and a very conservative area at that, so there aren't any specialty clinics out here, and again approaching a regular MD seems fruitless.

So I've been taking Siterone (50mg) for around a week and some change. I took the first four days with extreme caution only taking one pill, especially with my body size. On the day the meds came in I was real excited, as I was told my pills would take 4-6 weeks to get there and it got there in a week if that, so it was an unexpected treat. I waited a few days after it arrived to begin my transition because the next couple days were pretty busy and stressing, and I wanted to begin on an easy and relaxed day. The first day I wasn't expecting much esp with just one pill but I noticed my testes felt kinda sore, not in a way you'd expect, but if you've ever had something in your eye and you end up rubbing at it too much. Over the next few more days I did everything carefully inspecting to find any red flags, all I got was a few aches and pains in my bones, sorta groggy and my skin felt kinda tingly. Slowly this has all been fading away as I think my body is begin to adjust.

I haven't got any radical changes emotionally, maybe a little more sensitive to certain stuff, maybe not. There is only one instance so far where I think I felt the pills might be affecting me during an argument I got in with my dad on a sensitive topic, even though I knew it'd go nowhere we continued to bicker, and I ended up spitting on him. It was a bad day for the both of us and I feel like that maybe it might of brought on by the pills a little (At least the spitting part.) and made me a bit more hotheaded. I'm almost never reactionary like that. I don't think occurrences like that will be a ever lasting issue though, it was probably just the toll of the day.

Bumping up to two pills didn't seem to hurt, and I've been really happy with the results. No real intrusive thoughts no interrupting images, about the only time I think about that sorta thing is when I think about how I'm on Siterone, and it's not really sexualized. So, so far I've been really loving this and it's been working for me, no real horrors or overbearing pains, I feel like a monkey has been lifted off my back. Plus to boot, I'm moving across the country in a few months with a friend who currently lives in that area, I did some research and found a feminist clinic that works with transgender issues and transformations but they're willing to work with me using just T-blockers once I get there, and get everything done properly.

I don't know if I missed anything real important but ask questions, give advice, whatever. I'll probably post some more updates if you guys want in a few days. This is too awesome, couldn't ask for much more regarding my experience thus far, it's gone way better than I thought. I've told about three trusted friends and they've all been supportive of me which helps a shitload too. I know it's been only like 7-10 days or so but that's enough to have some sorta taste right?

Long term use or high dosages of Siterone can lead to liver problems. At 100 mg a day you should be ok. It has a cumulative effect so be patient and don't rush into taking more than you need. Once you achieve your goal you will be able to reduce the dosage. If you go above 150mg a day you really should get your liver function checked after 3 months. I used siterone for a prolonged period and I now have multiple hypodense lesions on the liver, which could turn malignant. It is a powerful drug, and does what it says on the tin, but it also has very bad side effects and they are often ignored.

If you don't already know it this is a really useful site http://www.transgendercare.com/ Take care and be patient.

100 mg seems to be working out fine right now. I'd give it time before feeling the need to bump up to 150 for a small streak, I've got the body size of a middle schooler.

One advice - avoid grapefruit and grapefruit juice in large quantities, it interacts with siterone and can lead to liver damage.

Keyword to google is

"Cytochrome P450 3A4"