Page 1 of 2

HRT after castration

Posted: Sun Apr 27, 2014 5:25 am
by MarionTG (imported)
Hello, to shut down testosterone forever a male need castration (chemically/surgical). The goal is to affected lower Libido and lessening to be a male, the goal. But the body needs homones. If you took estrogens, never testosterone, would feminize the body. Can you live in male-mode with the physical changes (if the breasts are not growing to big) and emotional changes? When stopping estrogens would the feminizing process go on because it`s a one way ticket?

Re: HRT after castration

Posted: Sun Apr 27, 2014 4:36 pm
by tugon (imported)
First let me say I have lived without any hormone replacement since 12/06/97. So it is not always true that hormones are needed. The lack of T alone can cause a male to feminize. Of course this can effect some more than others. I will let those with HRT experience answer further No T is the life for me.

Re: HRT after castration

Posted: Mon Apr 28, 2014 1:38 pm
by spoked451 (imported)
MarionTG (imported) wrote: Sun Apr 27, 2014 5:25 am Can you live in male-mode with the physical changes (if the breasts are not growing to big) and emotional changes? When stopping estrogens would the feminizing process go on because it`s a one way ticket?

The emotional changes are a personal thing, so only you can be the judge. If you're on estrogen, begin to to see feminizing traits (breast development, skin softening, fat redistribution) and stop so should the feminization. Most see the traits regress a bit, some just stop where they are, but I haven't heard of anyone that's just had things keep on developing in the absence of estrogen.

Re: HRT after castration

Posted: Mon Apr 28, 2014 4:36 pm
by Woggler58 (imported)
Most males who need shut-down of testosterone and get drug-induced or surgical castration are older men who have prostate cancer still uncured after treatments that failed to kill it and cannot be tried again. Lack of testosterone causes prostate cancer growth to slow way down for usually many years...and also makes those males into eunuchs.

I am a male who may have uncured prostate cancer after 6 years, or may not -- but I study the effect of taking estrogen to reduce some effects if I become a no-testosterone eunuch in the future.

I understand that all non-castrated men make their own estrogen by converting some of their own testosterone (T) and that all men need at least 20 pg/ml of estradiol (E2, a major form of estrogen) for good health. After castration they have no T as a raw material and will have no E2 because of it.

If my cancer returns and stays, I expect to go for surgical castration and take at least low-dose E2, because it will lessen many unwanted quality-of-life effects of no T, also because a natural metabolite of E2 is believed to have its own anti-cancer growth properties -- so I read in a medical journal abstract. But I will have more breast growth and other feminizing effects than if I merely lack T. Yet if I am to be a eunuch, so what? "In for a penny, in for a pound."

Older men produce less natural T but convert more of it to E2. More than 50 pg/ml E2 is not wanted. Prescribed, low-dose Anastrozole (Arimidex) reduces this conversion. I take prescribed T for under-performing testicles and take Arimidex to hold down E2 to 30-45 pg/ml.

I understand that T is necessary to suppress breast organ growth and nipple sensitivity in men because in both genders breast glands will grow if T is not present (or if present and is not overwhelmed by E2 as it is in women.)

In the EA Forum on Cancer-Prostate and Testicular, there is a posting several years ago which discusses effects and their mitigation measures of men with prostate cancer who have had their T reduced to castrate-level. I do not recall addition of E2 being considered.

Some prostate patients use high-dose E2, applied through their skin as a gel to minimize adverse cardiovascular effects, to obtain chemical castration and lessening its annoying effects at the same time. Reportedly there is a lot of breast growth. Search for published articles about and by Richard J. Wassersug, PhD, who I understand is familiar with high-dose E2 as a sole treatment for recurrent prostate cancer.

Re: HRT after castration

Posted: Wed Apr 30, 2014 12:37 pm
by MarionTG (imported)
How fast minimized androcur the testosterone production? Could it reactiveted after estrogentherapie? How fast could it reactivated and the feminizing effect would then stop? Because after stopping estrogentherapy after castration stopped not abruptly.

Re: HRT after castration

Posted: Wed Apr 30, 2014 6:19 pm
by janekane (imported)
Somewhat after my orchiectomy, I came under the care of an internationally recognized endocrinologist, who prescribed for me a premarin-progesterone monthly administration. That went on for a while, until I arrived at the upper end of the range of normal menopause, whereupon, for bone mineralization purposes, he prescribed a bisphosphonate medication and ample exercise.

However, I have regarded myself as being somewhere in the transgender realm since I was a toddler.

Re: HRT after castration

Posted: Thu May 01, 2014 10:46 am
by _g (imported)
MarionTG (imported) wrote: Sun Apr 27, 2014 5:25 am Hello, to shut down testosterone forever a male need castration (chemically/surgical). The goal is to affected lower Libido and lessening to be a male, the goal. But the body needs homones. If you took estrogens, never testosterone, would feminize the body. Can you live in male-mode with the physical changes (if the breasts are not growing to big) and emotional changes? When stopping estrogens would the feminizing process go on because it`s a one way ticket?

Please note if you wish for flat chest, you will need to take an anti-estrogen. Testosterone has a longer half life in the body than estrogen, a damaged liver stops converting estrogen and that is why some alcoholics and drug users end up with Breast growth. Once you have breast tissue it does not go away, and once you have breast tissue exposure to more estrogen like food will cause the breast to grow. Now if it's just fat the lose of weight will cause the breasts to get smaller or go away.

Re: HRT after castration

Posted: Mon May 19, 2014 2:59 pm
by mrt (imported)
Hi everyone. I haven't haunted the board for a long long time. I hate people who only show up when they want something but.... Here I am! I'm in that prostate cancer boat. I've got the unfortunate mix of Prostate cancer and no testes so I don't make my own testosterone and the Docs say absolutly no more testosterone injections, creams etc for a long while (if ever)

I'm going nuts. My cognitive powers are zilch. 1 + 2 = what was the question? err 12? So - my GP suggested talking to my Endo about estrogen while I get together with the urology folks to hack out the prostate. My endo has never had this situation so... Does anyone have some links or suggestions on either some mainstream "ok" for low dose estrodiol or maybe another plan? I never wanted the Eunuch Calm. *I'm not sure I want the Estrodiol side effects either but? What else is there.

BTW to those who do want the Eunuch Calm etc its all good I'm not finding fault with anyone else.

Re: HRT after castration

Posted: Mon May 19, 2014 5:04 pm
by Testman29 (imported)
Estrogen actually causes prostate cancer.

You really know what you need, Mr T? Is some pure anabolics such as EQ, or even some Deca. Yeah your sex drive will dip below what testosterone does but will be higher than having no testosterone. And your other functions that you mention, such as mental clarity and energy levels will all be right up there with what testosterone does. The pure anabolics like EQ should little to no effect of cancer cels of the prostate. unfornatly, its not legal to precribe.

Re: HRT after castration

Posted: Mon May 19, 2014 5:47 pm
by mrt (imported)
Anabolics (Steroids)? Aren't you thinking of something else? The wiki page on anabolic steroids shows a bottle of Testosterone Cyp. Testosterone to prostate tumors is like adding gasoline to fire. I'm pretty sure your wrong about estrogen. My family has a lot of prostate cancer and the only one thats lived any length of time is taking a testosterone blocker and Estrogen. The estrogen fills up the testosterone receptors so what testosterone you have isin't doing anything. Estrogen helps him think clearly but of course its got baggage with the moods and emotion and feminization issues.

*And while testosterone doesn't cause prostate cancer, like I said earlier it grows the piss out of it. Thats why guys who have uncurable prostate cancer do this mix of castration and estrogen. It helps them live longer and with better quality of life.