Hi everybody,

I'm new here and figured this was a good place to start. I am 27 years old, born male, and I am diagnosed with Asperger’s, major depression, and Gender identity disorder. I have been on Lupron Depot for the last 5 months. Outwardly I am Male but internally I am Null gender. I have been in therapy for about 3 years now. Ultimately I desire to have all my Male bits removed. I have no sexual desire what so ever. I am on my way to having my testicles removed. So far being on Lupron has removed Nighttime erections and much sexual frustration.

My experiences with relationships or other people in general have been very frustrating. I have found I am very good at making small talk and even flirting to various degrees. However I have absolutely no sexual arousal. After a falling out with longtime friend I feel into a very deep depression which cumulated in an attempt to perform some self-surgery involving zip-ties and a sledge hammer. After about 10 days in a Mental Hospital and many weeks of Intensive Outpatient Therapy. I was able to get my depression under control. I started seeing a Gender Specialist and then soon a visit to an Endocrinologist.

At any rate that is what has brought me here. I hope to find some people who are in a similar “boat” so to speak. Is anybody else on Lupron? So far it had been working well for me. Until my last injection. It went well in the clinic. It was a typical drop your pants, a quick poke, and you’re done kind of event. It was not until I was getting out of my bath that I noticed my band aid had blood. I thought no big deal but then I remember the instructions:

After cleaning the injection site with an alcohol swab, insert the needle completely at a 90 degree angle.

NOTE: Aspirated blood would be visible just below the lower lock connection if a blood vessel is accidentally penetrated. If present, blood can be seen through the transparent LuproLoc® safety device. If blood is present remove the needle immediately. Do not inject the medication.

The Next day I started having back pain, nausea, weakness, and fatigue. I also got really upset and threw something against a wall. My dad saw and got me to calm down and eventually I got back to normal in terms of my mental health. I’m probably reading way too much into this but my theory is it hasn’t killed me and I am still able to work. The dosing guide on the Lupron website does not mention what happens if somebody injects the stuff straight into your veins. http://www.rxabbvie.com/pdf/lupron7_5mg.pdf

Does anybody have thoughts and or comments?

Thanks,

AWGTHTGTATA

I've posted ad nauseam about my year and a half on Lupron. I was injected every 3 months as part of prostate cancer treatment. I experienced hot flashes, loss of libido and a don't give a shit outlook on life and didn't know why. Once I started reading up on it via internet and put 2 & 2 together I told the urologist I didn't want anymore of it. He said as long as my PSA remained low it was OK. I figure at $1300 per injection they would have left me on it for the rest of my life. After a while off Lupron I started feeling like my old self again. As far as I'm concerned that stuff is poison. At close to age 70 my libido isn't anything like it was years ago but I still like having a little bit. I'm no doctor but based on my own experiences I'm not at all surprised you're throwing things and depressed. Anybody ever gets near me again with a syringe full of that stuff they'll find out how much fight is left in this 'ol guy.