A little over a year ago I tried androcure as a trail run for castration. I was only on it for about four months, and I was extremely happy, unfortunatly I had to stop due to an elevated enzyme panel on my liver. As a hep B carrier this worried me and i stopped. I have also tried alcohol injections and have not had good results. Is there an alternate drug that is less stressfull on the liver.

Any help would be greatfully accepted.

Thank you all,

AtlantaJim

AtlantaJim (imported) wrote: Tue Jun 19, 2012 5:27 pm A little over a year ago I tried androcure as a trail run for castration. I was only on it for about four months, and I was extremely happy, unfortunatly I had to stop due to an elevated enzyme panel on my liver. As a hep B carrier this worried me and i stopped. I have also tried alcohol injections and have not had good results. Is there an alternate drug that is less stressfull on the liver.

Any help would be greatfully accepted.

Thank you all,

AtlantaJim

Spiroaldactone has more of a dieuretic effect and less taxing on the liver. also depo provera is effective , as many states use it for chemical castration programs , so it has to be safe,

but it has a slight femininizing effect as it is a female hormonal direvitive

I did use Depo provera for a long time. Worked very well for me.

superchef (imported) wrote: Tue Jun 19, 2012 6:28 pm Spiroaldactone has more of a dieuretic effect and less taxing on the liver. also depo provera is effective , as many states use it for chemical castration programs , so it has to be safe,

but it has a slight femininizing effect as it is a female hormonal direvitive

Depo Provera (medroxyprogesterone acetate) is used precisely because it has less feminising effects than any other male hormone reduction regimen - in particular, no gynaecomastia (breast development). I've been on DP and farlutal, a higher-strength injectable version of the same thing, and had no such effects. Until the 1960s oestrogen was used and it did the job but did cause gynaecomastia. Androcur can as well, if you're on it long enough (tamoxifen cuts that out, because it's an anti-oestrogen agent). DP is also much less hard on the liver than Androcur. One person on here has reported that his liver suffered when he was on DP, but that's quite rare. It's the most effective and best-tolerated drug for this purpose that there is.

Hmm... There are different ways at this:

You can block the action of T with androcur. It doesn't lower T but just the effects of it. Some folk produce more T as the pituitary gland calls for more to be made.

DP - essentially a long-acting progesterone is what maintains a pregnancy, and the fluid retention etc that often goes with it. Some say not so enjoyable, but each to his own.

Spiro is a diuretic, not strong but causes retention of potassium. Many effect of this but care is needed with heart medication and other blood pressure meds. Its anti androgen effect is not strong.

Never seen mentioned here, but try a Google of Leuprolide. This is an injection every one or three months. It takes about a week to stop the signal to produce T. T levels typically fall to like surgical castration. The effects are similar, flashes, weight gain, oseoporosis etc. T levels return gradually on cessation. In short it is the nearest thing to the knife, and often the drug of nchice forn prostate cancer, rather than orchie. Downside? It's expensive, though available worldwide.

Whatever you do, do it carefully! Community use of these meds is often not what they were made for, so you're on your own to very great extent.

I thank all of you for responding I guess what I am trying to figure out is Depo the only form of t blocker that can be injected i tried cyperterone and that lead me to the liver issues my research indicates that in my case an injectable is a better route.

"

Caponized (imported) wrote: Wed Jun 20, 2012 8:36 am It doesn't lower T but just the effects of it.

"

I have to disagree with that statement. After over five years of chemical castration with Cyproterone Acetate (Androcur, Siterone), my uncastrated testosterone level is between 600 and 700. It wasn't measured before my castration, but I suspect it was even higher then. While I was taking Cyproterone, my T level was below 100. My endocrinologist explained to me that, while Cypro blocks the effects of T, it also floods the blood with a chemical that looks so much like T that the body thinks there is already plenty and shuts down testicular production. The only testosterone I had was from Adrenal sources, just like for a woman. The max normal T levels for a woman are up to 75. In addition, the Cyproterone blocks most of the T that is left, so my body "saw" virtually no testosterone.

My endocrinologist monitored my liver enzymes, along with bone density, lipids, and glucose. My lipids, which have always been high, were up a little, glucose was ok, and liver enzymes were in the normal range. My bone mineral density was not good.

Provera (Don't call it "depo". Depo just means injectable) is progesterone, a female hormone. As I understand it, Provera has worse side effect in "men" than other drugs. It is not used in chemical castration because it lacks side effects; it's used because it's cheaper than other castrating drugs with less side effect.

I'm on estridol gel for my estrogen and finastracide pills to block the bad T