I am a very healthy man in my 20s. I want to experience temporary chemical castration. My goal is to reduce my libido - low for a while, then to zero - and temporarily lose the ability to have erections. I want to do this to gain some perspective. I hope that reducing my libido will make things better with my fiance. I hope that knocking it out entirely will let me realize how much of my life I spend chasing sex. Then I need it to recover, because I have no intention of becoming a eunuch and will one day want to have children.

My plan is to take Androcur, 150 mg daily for a few days, then down to 100 mg or maybe 50 mg. Anecdotally, my sex drive should be gone in 2 weeks. I know my mileage may vary, but I hope that 2 weeks will be enough. I will then spend a day reflecting my life, the changes I will have seen in myself, yadda yadda yadda, and I will stop taking the pills. I hope that within a month things should have recovered entirely from such a brief stint.

I also plan on having Tamoxifen on hand in case I start having nipple tenderness. I don't expect that I will need it on such a short course, but I don't want any long-term souvenirs hanging off my chest.

My question to you is whether this seems reasonable. If not, what changes would you make? My three priorities, in order of importance, are reversibility, brevity, and complete libido-destruction.

The problem with your plan is that you will be eliminating all sex hormones in your body (testosterone blocked by Androcur and estrogen by Tamoxifen). This is a bad idea because sex hormone is not just useful for sex, but also several other things like bone density, skin health and oil, arterial wall flexibility, heart regulation via calcium, internal body temp regulation, and brain chemical levels.

Tamoxifen and also Raloxifene mitigate the bone density problem a bit by still acting like estrogen for that purpose. But it doesn't cover all the estrogen effects (or else it wouldn't be an estrogen blocker).

You really want to have at least a bit of either testosterone or estrogen. I think blocking both is not a good idea.

I took Tamoxifen daily for about five years. I didn't take any anti-androgen. I take the Tamoxifen because I find it makes me much more muscular and lean, and made my sex urges feel more good than bad (it is hard to explain but I guess the best way to explain it is instead of feeling like a pervert that has to masturbate constantly, I'm still horny but it just feels good).

However, after five years I switched to Raloxifene because I got a side effect from Tamoxifen which is becoming more widely reported -- your Achilles tendon starts to shorten and give constant pain. This is the sort of weird thing that these drugs do -- they affect so much in your body that literally lots of different things can go wrong.

Also, when on these drugs your liver is stressed. Your doctor will immediately pick up on it. I don't drink any alcohol at all, except rare social occasions. I take Milk Thistle daily which is supposed to help -- it does seem to make my liver function scores a bit better.

I actually suggest that if being oversexed is your problem (which is mine) that taking just Raloxifene is worth a try. You will still feel horny, but if you start going to the gym you'll start feeling like superman. I've recently started up at a professional boxing gym and I literally could out-exercise all the younger guys there. It is a bit of a paradox, but I found that becoming more manly (through estrogen suppression) actually made being oversexed feel better. Rather than being a soft-bodied guy masturbating furiously to porn, I become a really athletic, confident guy that gets a lot of female attention.

If that doesn't work, my next suggestion is try an SSRI drug like Celexa. If you're lucky you'll get the loss of libido side effect. I took that for a number of years when I'd been seriously trying to castrate myself, and ended up in emergency. The doctor there prescribed Celexa and within three days almost all my sex desire had vanished. Furthermore, when I did have sex I could last indefinitely -- it was pretty fun. I stopped taking it because it did make me feel a little spacey though -- people would comment that I always seemed distracted. However, generally it was worth it versus the self harm I was doing. By the way, I now keep a fast-acting SSRI called Priligy around which is used to treat premature ejaculation. I don't have that problem, but it can make me last for an hour (honestly) in bed. Also, I use it when I have emergency self-harm urges and quickly want to suppress my oversexed nature.

Anyway, this is a long-winded message, but is coming from someone who has walked down the whole oversexed path and tried a lot of things.

If you do go for chemical castration by anti-androgen, I think you should just go with the estrogenic effects if they happen because suppressing that as well will, in my understanding, be pretty detrimental to long-term well-being and could possibly do things like liver damage and cardiac problems.

I think you may have misunderstood me. I plan to take Androcur for 2-3 weeks. I may not use the Tamoxifen at all - I will just have it in case I start to have breast development.

Irishman (imported) wrote: Sat Jun 25, 2011 4:26 am I think you may have misunderstood me. I plan to take Androcur for 2-3 weeks. I may not use the Tamoxifen at all - I will just have it in case I start to have breast development.

Okay. But these things lead to another. If you have any desire at all to be sexless (even temporarily) you might find you continue or do it regularly.

For the temporary plan, I'd still suggest an SSRI. It works fairly fast (definitely within one week) and makes you really uninterested in sex (if you're one of the people affected that way). Celexa works well for me in this regard. Priligy is a really short term one and will take effect within an hour and affect you for about half a day. SSRIs are generally quite safe, unless you have bipolar tendencies, which can be amplified including suicidal thoughts.

The anti-androgens take a while to really get into the effect you are looking for. I think you'd want to do it for at least a few months. The first couple weeks will indeed start lowering your testosterone, less erections and stuff, but you'll be getting hot flashes, mood changes, night sweats and the force of your mental habits will probably continue. I find you also get curious about whether its working and so will still try to masturbate and have sex. If you're looking for the "calm" sexless mentality part and want that to actually sink in to allow deep introspection on your priorities I think you'd want to try three months.

Otherwise, yes anti-androgens are generally reversible. You may have to exercise to undo any weight gain and muscle tone loss, after you stop taking it.

SplitDik (imported) wrote: Sat Jun 25, 2011 6:49 am If you're looking for the "calm" sexless mentality part and want that to actually sink in to allow deep introspection on your priorities I think you'd want to try three months.

But at that point I would be putting myself at risk of permanent changes. I have no interest in risking permanent infertility or impotence.

I've seen some people on here saying that Androcur completely eliminated their sex drive in about 10 days. Isn't that possible?

From my own personal experience, I took 50mg of Siterone (aka androcur) twice a day. It took about 6 weeks to realize that it was effective. Erections and sexuality diminished. It was like watching a green grass yard go brown. Slow, but eventually, dead.

Lab test indicated my T level was below 150. Not super low, but low.

One thing with androcur and Siterone is that, from reading the literature that came with the drug, you should have liver function monitored ( I did not), and that once it becomes effective you should reduce the dose, AND when you decide to stop using it, reduce the dose by about 25mg once a week until you are "weened" off the drug ; do not stop using it cold turkey. I can't explain why, it got too technical.

From what I read, such short use of the drug should not cause permanent eunuch like effects.

But then, don't assume your results will be like anyone's results. One much do research, evaluate, and make a personal decision on what to do.

OH, PS: I know nothing about taxomifen, but for me, experimenting with one drug at a time is preferable so that if any side effects were occurring I would be able to evaluate that it was the one drug, and not know which drug was causing them.

You might be better off trying Depo-Provera - I know, it's all I've used, but it was very effective in reducing my desire for sexual activity. My spontaneous erections were eliminated, and sometimes I could get up if I put an effort into it, but there was much less desire (fantasy, etc.). One 150mg vial kicks in, in earnest, after a couple of weeks and the effects last a couple of months. It's been recommended to take a double dose to start with (sex offenders, so I've heard, get more than even this.)

It's best taken as an intramuscular injection, and Inhouse Pharmacy sells it as ready-to-inject syringes. Not sure how easy it is to get it into the USA; I've read that if you're close to Mexico, you can go south of the border and buy it openly.

I have a few concerns with Depo. First, it is slower to act and longer lasting. I don't want to devote so much time to this. Second, feminization is a serious concern there, no? Perhaps it would be an alternative to Androcur, but I don't see any outright advantages.

The problem is that there is no way of stopping erections overnight and starting them again overnight. Androcur is also gradual in how it starts and stops working. I had no adverse symptoms such as hot flushes when I was on DP; men who have taken Androcur report otherwise.

i dont see any quick way to achieve your goals. the time frame that you have set seems very un-realistic. even if the drugs could achieve the goal of no sex drive in just 2 weeks how is aday or two of not having sex really telling you anything. the drugs did have a permanent effect on me, which i didnt mind, but i took them for over 2 years. I think a longer time frame is recommended for your experiment. good luck with it