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Post-finasteride syndrome?

Posted: Tue Dec 28, 2010 5:01 am
by Caith721 (imported)
Has anyone here ever used finasteride (proscar, propecia, fincar) for an extended period, stopped, and then experienced this emerging medical condition (http://mypropeciasideeffects.com/my-pro ... ptoms.html)? Apparently, a number of men with specific genetic coding experience an endocrine crash that doesn't resolve, even after years off the drug. The more experienced EA readers should easily recognize all of the symptoms listed on the web page.

Alan Jacobs, MD is a neuroendocrinologist documenting this syndrome and associated research on his blog. (http://alanjacobsmd.typepad.com/alan-jacobs-mds-blog/)

Re: Post-finasteride syndrome?

Posted: Tue Dec 28, 2010 12:09 pm
by billie_tv (imported)
Hi Caith721

I've read about that post Finasteride syndrome. I think though it'll take more time and studies for them to figure it all out. Genetics probably plays a factor because I know that there is a test to see if a patient will actually benefit from it as a MPB male pattern baldness treatment. Personally, I haven't been on it for more than six months, but it does cause some subtle changes. I'll read that article again. The Endocrine system is complex and it's fully understandable that the body reacts a bit like a pendulum, and sometimes it doesn't 'reset' to where you started off.

Re: Post-finasteride syndrome?

Posted: Tue Dec 28, 2010 4:36 pm
by bobbie (imported)
Caith721 (imported) wrote: Tue Dec 28, 2010 5:01 am Has anyone here ever used finasteride (proscar, propecia, fincar) for an extended period, stopped, and then experienced this emerging medical condition (http://mypropeciasideeffects.com/my-pro ... ptoms.html)? Apparently, a number of men with specific genetic coding experience an endocrine crash that doesn't resolve, even after years off the drug. The more experienced EA readers should easily recognize all of the symptoms listed on the web page.

Alan Jacobs, MD is a neuroendocrinologist documenting this syndrome and associated research on his blog. (http://alanjacobsmd.typepad.com/alan-jacobs-mds-blog/)

When every you start taking a drug the effects can be long term and may times not be revertible. Drugs like Finasteride effect on how the body makes testosterone. Think about it, you are taking a drug that is suppose to reduce the testosterone in the body. The effects can be permanent in some people. Age and many other factors can effect the long term effect. That is why it is so important to talk to your doctor about the possible outcome taking a drug.

Looking at your profile I do not know why you are taking this drug. The cyproterone acetate your are taking is far more powerful then what finasterice would produce. The dose of cyprotereone may not be enough to have the desired effect on reducing erections and emotional feelings. There are many threads about how much people have taken. 100mg a day is a good place to start at. Adjust the dose up or down after at least a month.

Re: Post-finasteride syndrome?

Posted: Tue Dec 28, 2010 5:38 pm
by Caith721 (imported)
bobbie (imported) wrote: Tue Dec 28, 2010 4:36 pm Looking at your profile I do not know why you are taking this drug. The cyproterone acetate your are taking is far more powerful then what finasterice would produce.

I'm not personally taking (nor do I need/want to) finasteride. I have taken Avodart (dutasteride) for several weeks before, for BPH/BPE. But the symptoms of post-finasteride syndrome are so similar to what is desired by so many here, I felt it was a topic to be shared with everyone who may not learn of it, otherwise.

Re: Post-finasteride syndrome?

Posted: Tue Dec 28, 2010 9:13 pm
by billie_tv (imported)
Finasteride can result in serum levels of Testosterone actually 10% higher, sometimes more, than your pre Finasteride state. The reason being that the receptor sites are not able to bind with "DHT" Dihydrotestosterone, the more potent form that Testosterone gets converted to. But there are complex chemical pathways and multiple systems involved, so if you believe you are susceptible it's best to not take the chance. And like Bobbie said, Cyproterone acetate (Androcur) is more potent, and is most likely going to give you better results for what you want. Just make sure you are aware of all side effects and risk factors involved. It's always good to have a doctor monitor your usage.

Re: Post-finasteride syndrome?

Posted: Tue Dec 28, 2010 9:37 pm
by guillotineme2004 (imported)
meh...

The mind is a powerful thing folks and it loves connecting dots. I'm not sure I'm buying it.

I've been using the stuff off and on (economic reasons) for years. Trust me, if it effects libido, it ain't by much.

Overall though, I'd have to say the most this drug has ever really done is... lighten my wallet, it's expensive.

My personal take... get a short haircut and live with MPB...it ain't a big deal and some of the sexiest guys are thin up top.