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Info From Some Email re: Gonex, etc.

Posted: Sat May 18, 2002 4:46 am
by Paolo
Hey,

I was talking to a fan of your site today and he was saying that there is a fear among the folks that frequent your site about Neutersol in the food chain. First, I am not a human doctor...I am a vet. But this gives me a better perspective as vets are doing studies with this drug. I think that it is highly unlikely that it will enter the food chain. This is because it acts locally when it is injected into the testicle. It is caustic and fibroses the testicular tissue. Even if the testicle is eaten right after injection, it would probably just damage the oral cavity and gut. Right now, studies are being done in the US because it is not yet approved here. Most of the studies center on companion animals anyway.

You are welcome to post my email. I do not know anything about Gonex. From just a quick jaunt on the internet, it looks like an anti-GNRH antibody time thing. If this is so, it is most likely a protein. If, by some way, you orally ingested it, it would be digested/degraded by your enzyme system in your gut and your body would just use it as fuel. This is very simliar to the whole controversy over Bovine somatotropin (BST) which was spoofed on X-Files many years ago. See hormones are of 2 catagories. The steroid, or cholesterol based hormones (like estrogen, progesterone, etc) and the protein based (BST, Growth hormone). The fear initally was that BST would cross into the population and cause growth disturbances in the youth. However, only the very young (ie under 24 hours old) and those with very damaged guts (severe inflamation) could have intact proteins cross the gut. For the rest of us, the protiens have to be broken down to amino acids before absorbtion. A simple rule of thumb is, if they have to ingect an animal rather that feed it the drug, a hormonal drug is less likely to affect the one consuming the meat. Though, really, there is alot of post ingection testing that would have to be done to show a lack of residue in the animal before it would be allowed in food animals. There are alot of laws out there that protect the human population from consuming drug tainted food. Besides, I really find it hard to imagine that a bunch of USDA guys would allow something out there that could chemically sterilize them. There are still alot of men that will not castrate their DOGS because it would make them less of a man. Anywho, long story short, I doubt that Gonex would affect humans, but I am really not sure. Hopefully, it will make it onto the market because the cost of spaying/neutering dogs and cats is higher than what the vet charges the client...especially if you consider all of the charity work we do spaying/neutering at no cost to the shelters. Hope this helps!!!

Re: Info From Some Email re: Gonex, etc.

Posted: Sat May 18, 2002 4:49 pm
by Andrew (imported)
Thank you for posting this INFORMATIVE e-mail

πŸ“– πŸ“– πŸ“– πŸ“– πŸ“– πŸ“– πŸ“– πŸ“– πŸ“– πŸ“– πŸ“– πŸ“– πŸ“–

Re: Info From Some Email re: Gonex, etc.

Posted: Sat May 18, 2002 7:52 pm
by A-1 (imported)
The problem that I have with this is while it all looks good at first glance, if Gonex is given orally to an animal, then it stands to reason that some would be able to make it, albeit in trace amounts, into the body of someone who consumed the animal who was neutered in this manner.

Moreover, Prion borne diseases cross the species barrier, this is a proven fact. Prions are protien for the most part. Creutzfeldt-Jakob Disease is caused by Prions and Mad Cow Disease which is also caused by Prions crosses species barriers and affects humans. Both of these diseases are fatal. Creutzfeldt-Jakob Disease has appeared according to medical literature as a complication of the administration of human growth hormone.

So, with all due respect to the gentleman who is a Veternarian, I would rather see error be on the side of safety. This is not a problem to give to animals whose meat would never be given to human consumption.

However, sooner or later somebody may put a cat in the kettle at the Peking Moon and people could end up experiencing loss of sexuality. Or, worse yet, some profit-minded individual could use it on cattle or pigs and cause wide-spread problems.

As for the use on dogs, cats and other domestic animals, I see no problem here unless, of course, one starts eating them.

Just a respectful difference of opinion.

:) A-1:)

Re: Info From Some Email re: Gonex, etc.

Posted: Sun May 19, 2002 7:42 am
by Paolo
Somebody's been listening to that MP3 that's been flying around the Internet for some years now...

As I stated in the other thread about Gonex, though, one has to wonder. I do. Every time I read something about this, I keep thinking about how growth hormones leak into the beef, etc., etc., and how it seems that kids raised on fast food are bigger nowadays - not just fatter - but larger, taller, etc.

Looking at my generation, the one the was pretty much the starter of this trend in fast food as a regular dietary supplement, it only convinces me that it's true on the growth hormone part. I really don't think it cooks out.

Just a reminder of what I've also noticed here, as I also mentioned before - I know a lot of boys who consume at least one cheeseburger a day, and they're big boys. Not just fat, either. Then there's the boy 3 houses down from me who won't eat meat - he's almost 15 now, and looks and sounds like an 8-year old.

Something to think about.

Re: Info From Some Email re: Gonex, etc.

Posted: Sun May 19, 2002 3:55 pm
by JesusA (imported)
I think that our Veterinarian is absolutely right on part of his comment and quite possibly wrong on the rest. The chance that he is wrong worries me a great deal.

On Neutersol he is absolutely right. The product is a necrotic that kills tissue on contact. Sufficiently diluted it would have no effect and could not become an environmental hazard. It must be injected directly into the testicle to kill it and the action is swift enough that it would be impossible to disguise.

On Gonex, however, I'm not so sure. I have written to the president of the company with my questions, but he has not bothered to answer. I probably should have sent my e-mail from work so that the return address would have carried some weight.

Our veterinarian seems to have much more faith in the intelligence of FDA employees than my own experience has shown. From past interactions with them, I would never trust them to ask the right questions nor to follow through on the necessary testing.

I have written to various persons whom I hoped would take action (several news columnists, my congresswoman, both my state senators, Ted Kennedy, who is chair of the Subcommittee on Public Health of the U.S. Senate, etc.). I have had no positive response yet. When I do receive an answer, it has been a form letter that has nothing to do with my questions.

My reading of the Gonex site is that it IS a steroid-based hormone, much like the estrogen and estrogen analogues which are Þnally coming to be seen as a serious problem. It has taken 20 years and serious environmental contamination, together with serious damage to various species, to bring the problem to public awareness. There are now rivers in Japan with no mature male Þsh because of the concentration of estrogen analogues (including a popular Japanese laundry detergent). There is well-documented failure of male alligators to mature sexually because of estrogen analogues in the waters of the Gulf Coast.

A-1 and Paolo are absolutely right in their concerns. Even if Gonex were protein-based, Mad Cow Disease is caused by prions, which pass through the gut and into the bloodstream, contrary to what our vet would have us believe about protein-based matter. If protein-based prions can cross over, protein-based hormones may be able to as well. We don't have adequate testing information. A number of observers have commented on the fast food - growth connection that Paolo brought up, though there is no good research that I am yet aware of. It certainly seems to Þt my personal observations as well.

We can HOPE that everything will be all right, but I would much prefer to have someone with some power and visibility provide oversight and ask the nasty questions about Gonex that I feel are necessary.

Any readers of the Archive who live in a state represented on the Subcommittee on Public Health might want to write a letter as a constituent. They might get a better response than I got from a senator from the other side of the country. The Senate site listing the members of the subcommittee is http://labor.senate.gov/Subcommittees/P ... health.htm

Readers living in New York probably needn't bother writing to Senator Hilary Clinton. She would probably wish that Gonex had been readily available ten years ago. (Seriously, she might turn out to be the most responsible member of the subcommittee, and I plan to write to her. Another letter from a New York constituent would probably help her aides decide to follow through.)

Re: Info From Some Email re: Gonex, etc.

Posted: Tue May 21, 2002 11:37 am
by madscientist (imported)
What, exactly, is Neutersol & where is it sold?

Re: Info From Some Email re: Gonex, etc.

Posted: Wed May 22, 2002 7:43 am
by SplitDick (imported)
I agree with those who posted suspicions about the safety of hormones, etc. in our food chain.

I was very well fed all my life, and am 6'3" and 220lbs. But that is not even considered big anymore!

I saw an asian girl (about 17) yesterday who was taller than me. All my younger boy cousins are taller than me. One of them is 15 and has to bend down to go through a doorway!

There is also a huge rise in women requiring cesaerian sections because their babies are too big to birth naturally. That happened to my wife as well as three other women I know.

I am convinced it is more than nutrition because all my youth me and my generation ate huge, well-rounded meals. Something else is affecting human size, and growth hormone residue in meat seems like a reasonable explanation.