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Androcur, Spiro, Tamoxifen side effects; about

Posted: Mon Sep 08, 2008 5:16 am
by antoniovaldex (imported)
is tomaxifen any good for not feminization eg. no breast growth and fat redistrubution

Re: Androcur, Spiro, Tamoxifen side effects; about

Posted: Mon Sep 08, 2008 5:21 am
by antoniovaldex (imported)
i have heard that for some reason you are less likley to develop breats on androcur than spiro ,i think that this is total crap and would think you are much more likley to develop breasts on androcur

Re: Androcur, Spiro, Tamoxifen side effects; about

Posted: Mon Sep 08, 2008 5:22 am
by antoniovaldex (imported)
i have heard that androcur can make you bald,i hope this is not true

Re: Androcur, Spiro, Tamoxifen side effects; about

Posted: Mon Sep 08, 2008 6:51 am
by Paolo
From Drugs.com:

Description

Cyproterone (SYE-proe-te-rone) is used to treat cancer of the prostate gland. The prostate gland is present only in males; therefore, females do not get prostate cancer.

This medicine blocks the effect of the male hormone testosterone in the body. This decreases the amount of testosterone produced in the body and is one way of treating this type of cancer.

This medicine is available only with your doctor's prescription, in the following dosage forms:

Oral

Tablets (Canada)

Parenteral

Injection (Canada)

Before Using This Medicine

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For cyproterone, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to cyproterone. Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—Studies on effects in pregnancy have not been done in either humans or animals.

Breast-feeding— It is not known whether cyproterone passes into the breast milk. However, this medicine has not been reported to cause problems in nursing babies.

Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of cyproterone in children with use in other age groups.

Older adults—Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of cyproterone in the elderly with use in other age groups.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking cyproterone, it is especially important that your health care professional know if you are receiving any of the following:

Ethinyl estradiol (eg, Estinyl)—Concurrent use with cyproterone may cause blood clotting problems

Other medical problems—The presence of other medical problems may affect the use of cyproterone. Make sure you tell your doctor if you have any other medical problems, especially:

Blood clots (or history of) or

Circulation disease (or history of) or

Stroke (or history of)—If these conditions already are already present, cyproterone may have a greater chance of causing blood clot problems

Cardiac disease—May make the condition worse

Depressive tendencies—May cause depression to occur

Type 2 diabetes mellitus—May cause a loss of control of diabetes by increasing blood and urine sugar

Liver disease—Effects of cyproterone may be increased because of its slower removal from the body

Proper Use of This Medicine

At first, cyproterone often causes loss of strength and energy or tiredness. However, these effects are lessened after about the third month of treatment and it is very important that you continue to receive this medication.

This medication should not be discontinued even if improvement of the disease occurs.

Dosing—The dose of cyproterone will be different for different patients. The dose that is used may depend on a number of things, including what the medicine is being used for, the patient's body size, and whether or not other medicines are also being taken. If you are taking or receiving cyproterone at home, follow your doctor's orders or the directions on the label. If you have any questions about the proper dose of cyproterone, ask your doctor.

For oral dosage form:

For treating prostate cancer:

Adults—100 to 200 milligrams (mg) (2 to 4 tablets) a day divided into 2 to 3 doses and taken after meals.

For injection dosage form:

For treating prostate cancer:

Adult—300 mg (3 mL) injected into a muscle once a week.

Missed dose—If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage—To store this medicine:

Keep out of the reach of children.

Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.

Keep the medicine from freezing.

Do not keep outdated medicine or medicine no longer needed. Ask your health care professional how you should dispose of any medicine you do not use. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.

This medicine may cause some people to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert .

Cyproterone may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine:

Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.

Wear protective clothing, including a hat. Also, wear sunglasses.

Apply a sun block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your health care professional.

Apply a sun block lipstick that has an SPF of at least 15 to protect your lips.

Do not use a sunlamp or tanning bed or booth.

If you have a severe reaction from the sun, check with your doctor .

While you are taking cyproterone, be careful to limit the amount of alcohol you drink.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Abdominal pain or tenderness; agitation; back pain; black, tarry stools; blisters on skin; bloody urine; blurred vision; chest pain; chills; clay colored stools; confusion; cough; dark urine; decreased appetite; decreased urine output; difficulty swallowing; dilated neck veins; dizziness; drowsiness; dry mouth; fainting or light-headedness when getting up from a lying or sitting position; fast heartbeat; fatigue; fever; flushed, dry skin; fruit-like breath odor; general feeling of discomfort or illness; hallucinations; headache, sudden and severe; hives; inability to speak; increased blood pressure; increased hunger; increased thirst; increased urination; irregular breathing; irregular heartbeat; itching; loss of consciousness; lower back/side pain; mood or mental changes; nausea and vomiting; painful or difficult urination; pains in chest, groin, or legs, especially calves of legs; puffiness or swelling of the eyelids or around the eyes, face, lips or tongue; red, thickened, or scaly skin; seizures; shortness of breath; skin rash; slurred speech; sores, ulcers, or white spots on lips or in mouth; sore throat; stiff neck; stomachache; sudden loss of coordination; sweating; swelling of feet or lower legs; swollen and/or painful glands; temporary blindness; tightness in chest; unexplained weight loss; unusual bleeding or bruising; vision changes; weakness in arm and/or leg on one side of the body, sudden and severe; wheezing; yellow eyes or skin

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.

More Common

Decreased interest in sexual intercourse; inability to have or keep an erection; increase in sexual ability, desire, drive, or performance; increased interest in sexual intercourse; loss in sexual ability, desire, drive, or performance; swelling of the breasts or breast soreness in both females and males; unexpected or excess milk flow from breasts

Less common or rare

Bleeding, blistering, burning, coldness, or discoloration of skin; change in walking and balance; clumsiness or unsteadiness; hair loss; inability to move legs or arms; increased sensitivity of skin to sunlight; increase in bowel movements; loose stools; loss of strength or energy; muscle pain or weakness; paralysis of one side of the body; redness or other discoloration of skin; severe sunburn; soft stools; tiredness or weakness; unusual increase in hair growth; weight gain

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Developed: 05/02/00

Revised:

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

Hair loss doesn't seem to be one of the myriad reported side effects.

Re: Androcur, Spiro, Tamoxifen side effects; about

Posted: Mon Sep 08, 2008 6:57 am
by Paolo
From Drugs.com:

Spironolactone

Generic Name: spironolactone (spir ON oh LAK tone)

Brand names: Aldactone

What is spironolactone?

Feedback for Spironolactone

User Comments Avg User Rating 6 Comments (http://www.drugs.com/comments/spironolactone/)

8.5 Rate it! (http://www.drugs.com/members_comments_a ... dc_id=2105)

Spironolactone is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.

Spironolactone is used to diagnose or treat a condition in which you have too much aldosterone in your body. Aldosterone is a hormone produced by your adrenal glands to help regulate the salt and water balance in your body.

Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. Spironolactone is also used to treat or prevent hypokalemia (low potassium levels in the blood).

Spironolactone may also be used for other purposes not listed in this medication guide.

Important information about spironolactone

Do not use spironolactone if you have kidney disease, urination problems, or high levels of potassium in your blood. Do not use potassium supplements or other diuretics while you are taking spironolactone. Before using this medication, tell your doctor if you have liver disease, or if you use a steroid or another diuretic.

Avoid drinking alcohol, which can increase some of the side effects of spironolactone. Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.

Do not use salt substitutes or low-sodium milk products that contain potassium. These products could cause your potassium levels to get too high while you are taking spironolactone. Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Before taking spironolactone

Do not use spironolactone if you have:

kidney disease or are unable to urinate;

high potassium levels (hyperkalemia); or

if you are taking potassium supplements or other potassium-sparing diuretics such as Aldactazide, amiloride (Midamor, Moduretic), or triamterene (Dyrenium, Dyazide, Maxzide).

Before using spironolactone, tell your doctor if you have:

heart disease;

liver disease; or

if you are using a steroid, or another diuretic.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take spironolactone.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Spironolactone passes into breast milk and could cause harm to a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take spironolactone?

Take spironolactone exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Take each dose with a full glass of water. To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. It is important that you not miss any scheduled visits to your doctor.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using spironolactone.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking spironolactone. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Store this medication at room temperature away from heat, light, and moisture.

What happens if I miss a dose?

Take the missed dose as soon as you remember. I
Paolo wrote: Mon Sep 08, 2008 6:51 am f it is almost time for your next dose, skip the missed dose and
take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include drowsiness, confusion, red skin rash, nausea, vomiting, or diarrhea.

What should I avoid while taking spironolactone?

Avoid drinking alcohol, which can increase some of the side effects of spironolactone. Tell your doctor if you regularly use other medicines that make you light-headed (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to the side effects of spironolactone. Do not use salt substitutes or low-sodium milk products that contain potassium. These products could cause your potassium levels to get too high while you are taking spironolactone. Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.

Spironolactone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Spironolactone side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

numbness or tingly feeling;

muscle pain or weakness;

slow, fast, or uneven heartbeat;

feeling drowsy, restless, or light-headed;

urinating less than usual or not at all;

shallow breathing;

tremors, confusion; or

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

mild nausea or vomiting;

dizziness, headache;

gas, stomach pain; or

skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect spironolactone?

Before taking this medication, tell your doctor if you are using any of the following drugs:

lithium (Eskalith, Lithobid);

digoxin (digitalis, Lanoxin);

steroids such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others;

an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik); or

an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), piroxicam (Feldene), and others.

This list is not complete and there may be other drugs that can interact with spironolactone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about spironolactone.

Remember, keep this and all other medicines out of the reach of children. Never share your medicines with others and only use this medication for the condition prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Re: Androcur, Spiro, Tamoxifen side effects; about

Posted: Mon Sep 08, 2008 7:02 am
by Paolo
From Drugs.com:

Tamoxifen

Generic Name: tamoxifen (ta MOX i fen)

Brand names: Soltamox

What is tamoxifen?

Feedback for Tamoxifen

User CommentsAvg User Rating 0 Comments

5.0
Paolo wrote: Mon Sep 08, 2008 6:57 am Rate it! (http://www.drugs.com/members_comments_add.php?ddc_id=21
45)

Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow. Tamoxifen works by blocking the effect of estrogen on certain tumors. This may prevent the growth of tumors that are activated by estrogen.

Tamoxifen is used to treat and prevent some types of breast cancer. It is used in women who are at high risk for breast cancer and in women with DCIS (after surgery and radiation).

Tamoxifen
Paolo wrote: Mon Sep 08, 2008 6:57 am may also be used for other purposes not listed in this medication guide.

Important information about
tamoxifen

Do not use tamoxife
Paolo wrote: Mon Sep 08, 2008 6:57 am n without telling your doctor if you are
pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. Before using tamoxifen, tell your doctor if you are allergic to any drugs, or if you have liver disease, high triglycerides (fatty acids) in your blood, a history of cataract, or a history of stroke or blood clot. Also tell your doctor if you if you are receiving chemotherapy or radiation treatment.

If you are taking tamoxifen to reduce your risk of breast cancer, you may need to take your first dose while you are having a menstrual period. You may also need to have a pregnancy test before you start taking tamoxifen, to make sure you are not pregnant
Paolo wrote: Mon Sep 08, 2008 6:57 am . Follow your doctor's instructions.

Taking tamoxifen may increase your risk of uterine cancer, stroke, or a blood clot in the lung, which can be fatal. Talk with your doctor about your specific risks in taking tamoxifen
Paolo wrote: Mon Sep 08, 2008 6:57 am . To be sure this medication is not causing harmful effects, your
doctor may want you to have mammograms and to perform routine breast self exams on a regular basis. Your liver function may also need to be tested. Do
Paolo wrote: Mon Sep 08, 2008 6:57 am not miss any scheduled visits to your doctor.

Before taking tamoxifen

Do not use this medication if you are allergic to tamoxifen. Before using tamoxifen, tell your doctor if you are allergic to any drugs, or if you have:

liver disease;

high levels of triglycerides (fatty acids) in your blood;

a history of stroke or blood clot;

a history of cataract; or

if you are receiving chemotherapy or radiation treatment.

Taking tamoxifen may increase your risk of uterine cancer, stroke, or a blood clot in the lung, which can be fatal. Talk with your doctor about your specific risks in taking tamoxifen. FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not use tamoxifen without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use a non-hormonal form of birth control (such as a condom or a diaphragm and spermicide) while you are using this medication and for 2 months after your treatment ends. It is not known whether tamoxifen passes into breast milk or if it could harm a nursing baby. This medication may also slow breast milk production
Paolo wrote: Mon Sep 08, 2008 6:57 am . Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take
tamoxifen?

Take tamoxifen
Paolo wrote: Mon Sep 08, 2008 6:57 am exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.
Follow the directions on your prescription label.

Take this medication with a full glass (8 ounces) of water. Tamoxifen can be taken with or without food.

If you are taking tamoxifen to reduce your risk of breast cancer, you may need to take your first dose while you are having a menstrual period. You may also need to have a pregnancy test before you start taking tamoxifen, to make sure you are not pregnant
Paolo wrote: Mon Sep 08, 2008 6:57 am . Follow your doctor's instructions.
It is important to use tamoxifen regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. You may need to keep using tamoxifen for up to 5 years.
Paolo wrote: Mon Sep 08, 2008 6:57 am To be sure this medication is not causing harmful effects, your
doctor may want you to have mammograms and to perform routine breast self exams on a regular basis. Your liver function may also need to be tested. Do
Paolo wrote: Mon Sep 08, 2008 6:57 am not miss any scheduled visits to your doctor.

Store tamoxifen at room temperature away from moisture and heat.
Paolo wrote: Mon Sep 08, 2008 6:57 am What happens if I miss a dose?

Take the missed dose as soon as you remember. I
Paolo wrote: Mon Sep 08, 2008 6:51 am f it is almost time for your nex
Paolo wrote: Mon Sep 08, 2008 6:57 am t dose, skip the missed dose and
take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think
you have used too much of this medicine. An overdose of tamoxifen is not expected to produce life-threatening symptoms.

W
Paolo wrote: Mon Sep 08, 2008 6:57 am hat should I avoid while taking tamoxifen?

Follow your doctor's instructions about any restrictions on food, beverages, or activity
Paolo wrote: Mon Sep 08, 2008 6:57 am while you are using tamoxifen.

Tamoxifen side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using tamoxifen and call your doctor at once if yo
u have any of these serious side effects:

sudden numbness or weakness, especially on one side of the body;

sudden headache, confusion, problems with vision, speech, or balance;

chest pain, shortness of breath, or coughing up blood;

pain or swelling in one or both legs;

unusual vaginal bleeding or discharge;

irregular menstrual periods;

pain or pressure in your pelvic area;

fever, chills, body aches, flu symptoms;

pale skin, ea
Paolo wrote: Mon Sep 08, 2008 6:57 am sy bruising or bleeding;

new breast lumps; or

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yell
owing of the skin or eyes).

Less serious tamoxifen side effects may include:

hot flashes, warmth or tingly feeling under your skin;

bone, joint, or tumor pain;

redness or skin changes;

swelling in your hands or feet;

vaginal itching or dryness;

depressed mood, weakness;

weight loss;

nausea;

cough, sore throat;

decreased sex drive, impotence, or difficulty having an orgasm;
Paolo wrote: Mon Sep 08, 2008 6:57 am headache, dizziness; or

thinning hair.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome s
ide effect.

What other drugs will affect tamoxifen?

Many drugs can interact wit
Paolo wrote: Mon Sep 08, 2008 6:57 am h tamoxifen. Below is just partial list. Te
ll your doctor if you are using any of these medications:

aminoglutethimide (Cytadren);

bromocriptine (Parlodel);

cimetidine (Tagamet);

clozapine (Clozaril, FazaClo);

isoniazid (for treating tuberculosis);

letrozole (Femara);

methimazole (Tapazole);

nicardipine (Cardene);

pioglitazone (Actos);

rifampin (Rifadin, Rifater, Rifamate, Rimactane);

ropinirole (Requip);

ticlopidine (Ticlid);

a blood thinner (warfarin, Coumadin);

anti-malaria medication such as chloroquine (Arelan) or pyrimethamine (Daraprim), or quinine (Qualaquin);

HIV or AIDS medicine such as delavirdine (Rescriptor) or ritonavir (Norvir);

an antibiotic such as terbinafine (Lamisil);

a heart rhythm medication such as amiodarone (Cordarone, Pacerone) or quinidine (Quinidex, Quin-Release Quin-G);

medicine to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), or thioridazine (Mellaril); or

an antidepressant such as bupropion (Wellbutrin), clomipramine (Anafranil), desipramine (Norpramin), duloxetine (Cymbalta), fluoxetine (Prozac), imipramine (Tofranil), paroxetine (Paxil), sertral
Paolo wrote: Mon Sep 08, 2008 6:57 am ine (Zoloft), or tranylcypromine (Parnate).

This list is not complete and there may be other drugs that can interact with tamoxifen. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about tamoxifen.

Remember, keep this and all other medicines out of the reach of childr
en, never share your medicines with oth
Paolo wrote: Mon Sep 08, 2008 6:57 am ers, and use tamoxifen only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, ch
eck with your doctor, nurse or pharmacist.

Re: Androcur, Spiro, Tamoxifen side effects; about

Posted: Sun Feb 06, 2011 7:20 pm
by loveableleopardy (imported)
Thank you Paolo for posting this information.

Re: Androcur, Spiro, Tamoxifen side effects; about

Posted: Mon Feb 07, 2011 7:22 am
by nullorchis (imported)
I tried Siterone, it worked. But the cost, and all of the possible issues with drugs ultimately made me decide to take another risky route, that being TAI (teste alcohol injection). I would never recommend or suggest that anyone do this, for that would be irresponsible. And nobody should estimate that they will not suffer dire consequences from TAI just because someone else had good results. Nevertheless, I am having good results. Consider it luck. In the long run I hope that this will be a better alternative to drugs and their side effects. Apparently a few researchers in the medical field are actually pondering the same consideration. Even if medicine research develops a method that uses any kind of an injection into testes that stops testosterone production, you can be sure it will be much studied, discussed, evaluated, complicated, technical, and ultimately expensive. In the mean time, this little self-inflicted ginny piggy is a happy camper.

Re: Androcur, Spiro, Tamoxifen side effects; about

Posted: Tue Apr 26, 2011 6:09 am
by Negaatio (imported)
If I wish no breast growth at all, but I do want a lower libido, what is the best mix of these drugs I should take?

I have been taking Androcur for about 5 months. I took 100mg at first, then just for about a week I lowered it to 50mg to test if the effects were the same, but because it didnt give me the results I wanted, I changed back to 100mg. So basically I've been into Androcur 100mg most of the time.

It has shown some effect on libido, but now (about two days ago) it also shows some effect on breast growth. They are small, and it doesn't show to other people, but it bothers me, because they are tense and I dont want them to get any bigger.

I've already decided to lower my androcur dose but should I buy some tamoxifen too? I've read all this info and its good that it is there, but how do these two work together?

It seems tamoxifen comes in 10mg packages, so should I take like 50mg of androcur and 10mg of tamoxifen so that I would keep my libido low but I could get rid of this breast growth problem?

Re: Androcur, Spiro, Tamoxifen side effects; about

Posted: Fri May 06, 2011 8:56 pm
by hkeunuch (imported)
Negaatio (imported) wrote: Tue Apr 26, 2011 6:09 am If I wish no breast growth at all, but I do want a lower libido, what is the best mix of these drugs I should take?

I've already decided to lower my androcur dose but should I buy some tamoxifen too? I've read all this info and its good that it is there, but how do these two work together?

I had been taking Androcur and Tamoxifen combination for a few years. For me (and I gathered from others' posts on this board, which I recommend you search also), there has not been any interactions between the drugs.

Because one works on androgen and the other works on estrogen, your libido will drop very fast. I found the complete lack of any sexual/sensual feelings too eerie and lowered my maintenance level to 25 mg of Androcur and 10 mg Tamoxifen (i.e., 1/2 tablet each). I was happy with that level.

Tamoxifen further helps prevent development of osteoporosis due to low testosterone from the Androcur.