My wife takes spiro for a condition she has called PCOS. This spiro is prescribed by an american doctor and bought from a local drug store. I am taking inhouse spiro due to the lack of any doctors around central Texas (that I can find) that are willing to work with such issues. Every now and then Tammie will run out of her spiro and take mine. When she does we both notice a change in her symptoms of the PCOS going south. I have also noticed that after about a month on the inhouse spiro that I still cant seem to "feel" it working like I did when I was taking her spiro. I bought the inhouse spiro around may 08, while I was waiting for my spiro to come in I was taking her 100mg pills twice a day. When mine came in I started taking 4- 25mg pills twice a day. I bought the 25mg so I could adjust the dose down to 150mg a day total because her spiro would dry me out a little more than I wanted at 200mg total per day. I was drinking around 2 gallons of water per day (coffee in the a.m. pure H2O from there) and still felt a little dehydrated. On the inhouse at 200mg total I dont even pee that much more than normal. I stoped taking my spiro in june because I started getting morning erections again and I thought it might be a difference in makers, its a reach, but it was the only valid thought at the time. After a 3 week break I picked up my spiro again and have been on it for a solid month. I noticed a definate difference in my reaction this time out, within the 2 weeks I was taking her meds I found it difficult to get an erection, peed every 15 minutes (at least it seemed like every 15) was a little calmer (Im a very hyper person) and I was a little more dehydrated than I mould like to be. Now with the same time frame on the inhouse I can get an erection if I want to with spontainious erection happening less (but they still happen) I urinate roughly half as much and I am back to pacing around and eating my fingers.

I am normally fairly sensitive to any meds and I have a background in medicine so I am not being bitchy about my time frame. It just has me kinda wondering if anyone else is in a situation where you could see a difference.

Also, Tammie has been on spiro and progesterone cream for over a year and her doctor has not done a blood test since the initial one. She does have a diet that is low in sodium/potasium and a list of reasons to go to the ER (standard) I have mentioned to her doc that it might be wise to check her hormone and potasium levels, the doc told me that he has many PCOS patients and he normaly checks them every year and a half to 2 years unless they are symptomatic. Strange, we are SUPPOST to get checked a little more often than that but if it is an "actual" medical condition the protocol changes. I guess that is why I quit medicine.

Makes you think.

Two thoughts. One if your popping 4 tablets vrs 1 doesn't the drug dissolve different? I mean will the dose be the same?

My second thought is anyone buying meds from the internet is going to have a crap shoot for what they really get. The drugs from Inhouse (some anyway) appear to be made in India from what I understand. Is the quality better or worse then those made in the USA?