A Question for Jesus.

[madscientist (imported)]

You seem to have a vast reference source available to you so perhaps you can tell me: Is it possible to permanently castrate oneself with Depo-Provera &, if so, what are the doses & frequencies of use? The product sheet says " Depo-Provera in appropriate doses suppresses the Leydig cell function in the male" but does not specify the dose. Perhaps you can find out.

[JesusA (imported)]

It will take me a while to do a literature search. This is certainly not one of the uses with FDA approval (or testing). Any anecdotal notes in the literature would be from accidental or "accidental" errors in administration. My immediate guess is that the dosage required for permanent castration is either too inconsistent to provide a useful indication for the medication or is accompanied by serious side effects. Otherwise, the Gonex Corporation would not be pushing its potential medication so hard. Gonex seems to think that they will be filling a niche that is still open.

There are several other active contributors to the Archive who may have information to share. I hope that they will provide whatever they have access to.

[madscientist (imported)]

Remember, Gonex works after only one shot, so it would be more pleasant to take rather than a series of monthly or tri-monthly shots. It would also cost less. To the best of my knowledge nobody has ever established whether Depo-Provera is a permanent castrating agent or whether it must be taken for life. I believe that the subject of chemical castration is repulsive to those in the American medical industry.