ZeuterMe (imported) wrote: Tue Apr 14, 2015 2:58 pm I didn't even think about the possibility of significant inflammation within a membrane-bound space. That's why head trauma frequently results in removing part of the skull and stashing it in the abdomen for later use - the swelling causes pressure that damages sensitive tissues, since there's nowhere to expand.

(all from Bergh A, Collin O and Lisbrant E (2001). “Effects of acute graded reduction in testicular blood flow on testicular morphology in the adult rat.” Biology of Reproduction, 64: 13)

Jcat, I wonder what your sperm count would look like?

I have never been too worried about being fertile! After all the testicle in jections and now this I doubt there are any swimmers strong enough to survive! My last T count was 48.99 ng/dl. That was way back last year. My LH & FSH are zero.

Some years ago I came across an article that stated that once a testicle became inflammed due to testicular torsion it was likely that the immune system would then attack BOTH testicles causing bilateral testicular atrophy, though this "effect" is only restricted to post pubertal males. To date I have never seen any other reference to this phenomena, so how valid this claim is, is open to conjecture! The reason for mentioning this possibility it that someone wishing only to kill one testicle using methods such as the burdizzo clamp or injections etc., might be in for a bit of a surprise especially if they have any plans for having sproglets. If that is the case then bank first, inject latter is the bast course of action.

Tante Wippen (imported) wrote: Wed Apr 15, 2015 2:54 am Some years ago I came across an article that stated that once a testicle became inflammed due to testicular torsion it was likely that the immune system would then attack BOTH testicles causing bilateral testicular atrophy, though this "effect" is only restricted to post pubertal males. To date I have never seen any other reference to this phenomena, so how valid this claim is, is open to conjecture! The reason for mentioning this possibility it that someone wishing only to kill one testicle using methods such as the burdizzo clamp or injections etc., might be in for a bit of a surprise especially if they have any plans for having sproglets. If that is the case then bank first, inject latter is the bast course of action.

I've seen reference to it in college immunology books.

T-cell training occurs during prenatal development - t cells are trained to ignore proteins making up the body.

Testicular development occurs during puberty, long after T cells are done. Inevitably, one of them is statistically certain to be autoreactive to either sperm or at least one epitope (https://en.wikipedia.org/wiki/Epitope) any of the - if I remember correctly - 999 documented novel proteins occurring only inside the testicle, beyond the blood-testis barrier (https://en.wikipedia.org/wiki/Blood%E2% ... is_barrier), where if the immune system could get in there a severe inflammatory response would happen.

The antibodies would recruit cytotoxic cells like the natural-killer cell (https://en.wikipedia.org/wiki/Natural_killer_cell) to begin destroying tagged cells and proteins, resulting in necrosis. Necrosis spills intracellular contents, exposing more exciting proteins to the immune system.

This will then compound as macrophages crawl into the testicle, through the (now leaking) blood-testicle barrier, and continue destroying cells and further recruiting more white blood cells, which have now proliferated into a large army of PLEASE DIE NOW.

Soon, you'll have balls the size of limes that produce nothing but inflammatory cytokines (https://en.wikipedia.org/wiki/Cytokine).

Source: I set the curve in college immunology and easily aced pathogenic microbiology.

Well, it won't be for much longer as I plan to take some steps to get fixed. Last night I injected about .20ml of calcium chloride under the skin of my scrotum. It formed a small bubble and then flattened out to a 2cm area. Within an hour the skin turned grey. No pain, nothing more than a pin prick on injection. Today, it is almost black.

I figured if it gets out of control it is a small enough area for me to slice off and stitch up.

We shall see what happens. I have a plan.

So some days ago my left testicle was removed surgically. The veins were completely blocked in the vas and there is no doubt that injecting did this. I am fairly confident that 2 well placed injections just above the epididymus would kill a testicle in one session, because it stops the blood flow as if it were a strangulation.

I am afraid that this is the end of journey as far as the vas is concerned.

I am delighted to be halfway to becoming a fully qualified eunuch too.

There will be more to follow of my journey in a new thread very soon.

Jcat, what happened to the spot where you injected calcium chloride under the skin of your scrotum? What urologist said about it?

What did biopsy of the right testicle shows?

GenChick (imported) wrote: Fri May 01, 2015 5:56 pm Jcat, what happened to the spot where you injected calcium chloride under the skin of your scrotum? What urologist said about it?

What did biopsy of the right testicle shows?

Hi Gen, They are puzzled, necrosis occurs in the genitals for a number of medical conditions, none of which I have and they have no explanation, wondering about trauma etc. The spot turned into an area that was quite big. They have removed the skin and plan to use what is left to close the wound up. They did not do a biopsy, they plan to remove it too. The trauma and infection was so great they want to do it in stages.

I say this with caution. It applied to me and my experience only. I can not make this a formula or rule for others. For me I injected a number of times under the skin over a nine day period and eventually went to ER. The effects were necrosis of the scrotum and I have suffered no ill effects from this. In spite of the infection, it is localised and all there is was a raised white cell count. This is my mileage and I cannot say it would be the same for others. Just asmy injections to the vas came after numerous injections to the testes and I have ni idea what effect it would have on some virgin balls.

The final analysis of the cords are that there was total ischemia or lack of blood supply to the testes. I think that 2 well places Vas injections of CaCl will kill the testes in one one session. I am surprised that there is so little feedback to this thread. This is a simple, quick method.

I will be posting some pictures on malebodymods in due course.

This was a good read jcat, I'm in the position where my right testicle is to be removed within the next couple of months, but whilst my left is atrophied,it is not showing any other 'irregularities' so they are leaving it alone... I think it's going to be difficult to inject into again as it's so small (about the size of a plump almond) so the spermatic chord looks like an option although I have quite a large varicocele which might complicate matters ... will be giving this some thought over the next few days... one down (almost) and one to go !

jcat (imported) wrote: Sun May 03, 2015 2:24 am The final analysis of the cords are that there was total ischemia or lack of blood supply to the testes. I think that 2 well places Vas injections of CaCl will kill the testes in one one session. I am surprised that there is so little feedback to this thread. This is a simple, quick method.

I will be posting some pictures on malebodymods in due course.

Can you explain me ... How i find my vas and how i should do the injection best ?