Wolf-Pup (imported) wrote: Thu Oct 08, 2015 12:50 pm I thought Tamoxifen blocks E? Taking both would be like taking testosterone + antiandorgen wouldn't it?
Maybe I am mistaken on how Tamoxifen works?
Yeah, I was confused on this too and had to dig into it a bit. Tamoxifen is a selective estrogen receptor modulator (SERM). It only blocks the absorption/use of estrogen by certain tissues, most importantly in breast tissue (but also perhaps in the brain, leading to some cognitive effects, "brain fog."). There are other drugs that slay estrogen throughout the body (or more accurately, prevent its synthesis), like anastrozole. Will confirm with my MD and share more.