Something, i hope this time the injection works well in that rebel teste. I need to be more bravery to do this, it's easy to say it, but when you have the syringe between the fingers and pass the minutes to find a white spot in the skin of the scrotum and, when has been found it, you get scared at the last moment... is very tired, phisically and mentally,at least for me.

Just a brief update since I have been away for a while and the thread seems to need a boost :O)

Both testicles appear to be hard and elongated/flat and are about 1/3 smaller overall. It is difficult to describe but they feel strange to the touch and are not very sensitive at all. It's almost as if they have shut down but have not continued to shrink. The latter is what surprises me the most since the research articles claimed continuing shrinkage over several months? My scrotum also feels cold when I wake in the morning, as if blood flow has decreased, something that I do not recall happening before the shots. I'm going to make an appointment with a urologist soon and get a T test and overall exam and I'll post the results once I get them.

Be well and be safe!

Brooke

BrookeTS (imported) wrote: Fri Feb 01, 2013 7:02 pm Just a brief update since I have been away for a while and the thread seems to need a boost :O)

Both testicles appear to be hard and elongated/flat and are about 1/3 smaller overall. It is difficult to describe but they feel strange to the touch and are not very sensitive at all. It's almost as if they have shut down but have not continued to shrink. The latter is what surprises me the most since the research articles claimed continuing shrinkage over several months? My scrotum also feels cold when I wake in the morning, as if blood flow has decreased, something that I do not recall happening before the shots. I'm going to make an appointment with a urologist soon and get a T test and overall exam and I'll post the results once I get them.

Be well and be safe!

Brooke

Hi Brooke,

Thanks for the update. I have been following the thread with great interest. Your posts are very clear and helpful. Good luck with the urologist

Missouri_Steer (imported) wrote: Tue Jan 22, 2013 6:04 pm From what site did you order your testosterone test kit? What's the URL? Does it give you the results right then or do you need to send it in to have a test run on the sample?

Actually you pay for the test online, but then go to an actual clinic to get the blood drawn. I would not trust the accuracy of a saliva test.

Anyway, I buy them at Personalabs.com. They are related to Lab Corp, which has locations all over and are a major lab services company.

Anyway, I just got my blood drawn today. Should get results in about 5 days. I chose the "basic female hormone profile" because it includes the sensitive testosterone test also useful for hypo males and because I like to also know my estradiol and luteinizing hormone levels. But there are cheaper testosterone only tests.

Well keep you posted on results.

SplitDik (imported) wrote: Wed Feb 06, 2013 10:51 am Actually you pay for the test online, but then go to an actual clinic to get the blood drawn. I would not trust the accuracy of a saliva test.

Anyway, I buy them at Personalabs.com. They are related to Lab Corp, which has locations all over and are a major lab services company.

Anyway, I just got my blood drawn today. Should get results in about 5 days. I chose the "basic female hormone profile" because it includes the sensitive testosterone test also useful for hypo males and because I like to also know my estradiol and luteinizing hormone levels. But there are cheaper testosterone only tests.

Well keep you posted on results.

Okay, got my results today. The results are interesting. They show that I have NOT achieved castration but do have symptoms indicating "primary testicle failure". I'll explain. First here's the results -- these are blood tests done by LabCorp, and I paid for an extra-accurate testosterone test.

Estradiol measured = 18.1 pg/mL, reference range (adult male) = 7.6-42.6, Normal

Testosterone, Total, LC/MS measured = 539 ng/dL, reference range (adult males > 18 yrs) = 348 - 1197, Normal

LH measured = 7.1 mIU/mL, reference range = 1.7-8.6, Normal

FSH measured = 21.2 mIU/mL, reference range = 1.5-12.4, Very High

TSH measured = 1.310 uIU/mL 0.450-4.500, Normal

Thyroxine (T4) measured = 8.2 ug/dL, reference range = 4.5-12.0, Normal

T3 Uptake measured = 35 %, reference range = 24-39, Normal

Free Thyroxine Index measured = 2.9, reference range = 1.2-4.9, Normal

Now, I think my testosterone has been knocked down a bit, as previously I was in the high normal range of about 900 (I'll see if I can find any old test results). However, I'm obviously not castrate at this testosterone level.

However, my FSH (follicle stimulating hormone) level is very high, from 2 to 3 times normal. The guidance on the test results says that this indicates primary testicle failure.

I researched it, and basically it is caused by having the Sertoli cells damaged (by trauma in my case obviously). These cells are almost solely involved in nourishing the sperm cells and are activated by FSH. When activated they are supposed to release a protein called inhibin which then causes the pituitary to reduce FSH production. A high FSH, like in my case, indicates that the Sertoli cells are completely damaged.

The primary effect is sterility -- you can read a lot about high FSH levels on infertility forums.

So basically it looks like the calcium chloride effectively sterilized me, but only knocked down testosterone a bit. I had 1cc of 33% injected into each testicle, although as discussed in the thread above, I think that is about half the dose needed for my originally large testicles.

Although initially I had same experience as others have reported -- a few days of extreme tenderness and swelling, than months of the testicles hardening and flattening, I do think they are recovering. They have regained a more egg-like shape and their consistency feels pretty normal. After several months of feeling truly castrated (low libido, no morning erections, difficulty maintaining erections), I've felt it creeping back.

So the conclusion of my experiments is this -- damage was done, but primarily to sperm production (Sertoli cells) but not testosterone production (Leydig cells). I didn't achieve castration this way. It may have been due to insufficient dose, or maybe is a reflection of the overall method.

It felt to me like they were damaged but recovered, so it is possible that repeated injection might create better results, but with the pain and uncertainty in outcome I wouldn't recommend it. I don't think I'll personally continue to re-inject, as when I originally injected I immediately regretted it -- castration for me is really a fetish more than a true desire. But we'll see -- the woman friend who injected me keeps asking me if she can finish the job (she was disappointed that the testicles didn't entirely shrink to tiny size as seemed to be promised by the literature).

Anyway, Something and Brooke, it would be great if you could get blood testing as well so we could get a better sense of real results. Based on my results, I would advise against using this method due to it not being effective for the castration purpose.

SplitDik, reading your results makes me think that you did not get the calcium chloride injected deep enough to kill the Leydzig cells in the core of the testicle. To be most effective, you really need to inject all the way to the core of the testicle. For me, that required at least a 1" needle when I did my alcohol injections.

TooMuchT (imported) wrote: Thu Feb 14, 2013 6:54 am SplitDik, reading your results makes me think that you did not get the calcium chloride injected deep enough to kill the Leydzig cells in the core of the testicle. To be most effective, you really need to inject all the way to the core of the testicle. For me, that required at least a 1" needle when I did my alcohol injections.

I don't think that explains it. Sertoli.cells line all the seminiferous tubules which form the majority of testicle tissue. these tubules are so packed into the testicle that a human has 600ft of them. I think high FSH indicates that

SplitDik (imported) wrote: Wed Feb 13, 2013 8:37 pm the calcium chloride effectively

permeated the entire testicle, otherwise the remaining Sertoli cells would inhibit it in proportion to the missed tissue.

SplitDik (imported) wrote: Wed Feb 13, 2013 8:37 pm Anyway, Something and Brooke, it would be great if you could get blood testing as well so we could get a better sense of real results. Based on my results, I would advise against using this method due to it not being effective for the castration purpose.

I have an appointment scheduled with a urologist on Tuesday. I'll be sure to post the exam and test results as they come in. After two months they remain hard and much smaller but not all that sensitive. However, the cords seem to be rather sensitive to the touch. I did manage to find a female urologist so I'm hoping that she is more open to removing them all together if the results show substantial atrophy and/or testicular failure.

Be well and be safe!

Brooke

Thought I'd post an update after re-injecting. The left one, which is the one that suffered the most damage initially, seems to not be doing anything now. It's much smaller than before, and well, is flat and hard still. Now, when I reinjected because the left one was tender at the time for some reason (I don't know why, it came out of nowhere), I only injected the right one. Afterwards, the usual pain started but I took painkillers before it got too bad. But here's what's interesting. The next day the pain was nowhere near as bad as the last time I did the injections, and by the end of the day it stopped hurting altogether... What's more interesting, is that now the right one is less sensitive to pain. Don't get me wrong, I can still feel pain in it, but not as much as before. I don't know why the pain stopped early this time. Right now it's still bigger and harder than before, but it didn't go down for quite a while last time so that's normal I guess.

I did notice a reduction in libido for a few days after doing the re-injection, but it's gone back to normal now. Since I only injected the right one this time, I'm hoping that means that the left one isn't producing as much testosterone, and the right one stopped temporarily for some reason (which might mean after a few weeks, the right one will stop again and then I'll be freeee!!). I'll try and get a blood test at some point, after a few more weeks have passed.

Splitdik,

Did you ever recieve the video of Ruby doing the injections?