nutless1 (imported) wrote: Wed Aug 02, 2017 2:52 am Wow! What interesting information. I wonder if the result is more widespread than just with this syndrome.

Tany Squirrel (imported) wrote: Wed Aug 02, 2017 1:50 am Having read this thread ( albeit a rather old one) , there is something to be said about this.

One has to consider, that if you have Gyneomastia or Kleinfelter's syndrome, you *may* be more prone to aromatization of testosterone into estrogen. This takes place in fatty deposits, (particularly the breast fat area as well).

If Gloriacowper had gynecomastia, and the fact that the areola's grew to 2.5 inches, this is a good indication that even the low T, whatever was free , was converted into Estrogen. This is of course, speculative, and with the reduction of the volume of the testicles, it would seem that the "positive " feed loop from hypothalamus and pituitary to testicles was closed. It creates a negative-feedback loop, where it tells the body to no longer produce testosterone, and in conjuction the adrenal glands and subcutaneous fat deposits were told to aromatize the T into E.

Once this "reprogramming" of the hypothalamus is complete, I do not think it is reversible. There are anecdotal stories on Transfemme website, where users of their product (mainly bovine ovaries and other glandulars, such as pituitary) experience the same "permanent" negative feedback loops where the remaining T is converted to E and feminization continues even after use of the product. (all of course subject to scrutiny).

So, with "milage may vary" in mind, pre-existing conditions of Gynecomastia theorheticaly would allow the Androcur to basically "nuke" what was left of the testosterone, and encourage the testicles to shut down completely, and use what is left via the subcutaneous fat conversion to exacerbate (or make worse), the pre-existing condition.

Be careful what you wish for. You may get it, but not how you wanted it.