I'm a transseuxal and I'm currently on 50mg Androcur plus estrogen patches and progesterone. I once tried 100mg androcur but that was too much. I felt tired and my sex drive went to absolutely zero (which i don't want). My hormone levels are in the range of a cis-female and I only can get a very soft erection with much stimulation. So I wonder if it's the estrogen that adds to the mix or we're just different. 150mg sound like very much in my experience.

butcherbaby (imported) wrote: Wed Aug 22, 2012 9:53 am I'm a transseuxal and I'm currently on 50mg Androcur plus estrogen patches and progesterone. I once tried 100mg androcur but that was too much. I felt tired and my sex drive went to absolutely zero (which i don't want). My hormone levels are in the range of a cis-female and I only can get a very soft erection with much stimulation. So I wonder if it's the estrogen that adds to the mix or we're just different. 150mg sound like very much in my experience.

I think it is estrogen which adds some energy plus some sexual drive. And most probably we are different too

I don't get one thing, high doses of androcur seem to cause tiredness and weakness. What is the reason? Too low T available in receptors or some Androcur sideeffects. As Androcur acts in many different ways not only by blocking T in receptors.

My question is, would surgical castration cause similar symptoms as high Androcur levels? Tiredness and weakness?

erikboy (imported) wrote: Wed Aug 22, 2012 3:34 pm I think it is estrogen which adds some energy plus some sexual drive. And most probably we are different too

I don't get one thing, high doses of androcur seem to cause tiredness and weakness. What is the reason? Too low T available in receptors or some Androcur sideeffects. As Androcur acts in many different ways not only by blocking T in receptors.

My question is, would surgical castration cause similar symptoms as high Androcur levels? Tiredness and weakness?

The fatigue and weakness is caused be a deficiency in testosterone. For some, the fatigue diminishes with time. For others it does not. Can't speak to the weakness of muscles - haven't heard too much about that diminishing. For me, the biggest problem was painful, arthritic joints, especially my legs.

So, two weeks now. Took last dose of androcur. Last milligram of this substance will be gone from my body by Monday.

It was interesting. I got better understanding what eunuchdom feels for sure. What was good that there was no big emotional fluctuations for me, I was most afraid of that. But I must say that trial was too short and inconclusive.

Tiredness is most annoying. I did not observe much loss in motivation to do things. There are changes in motivation base there of course. I use more of my rational thinking to stay motivated. Not having this urge: "I have to get this or that be done" Thats no big deal for me.

Yesturday I had strange feeling I never had before, I felt like my genitals are just a piece of meat dangling there. Hard to explain any better.

Today I woke up with very very soft hardness which was more feeling than a real hardness. It was supposed to be hard. Buzz like feeling is gone. There is some liberating feeling related to that. I remember that at times I could masturbate like 5 times a day without feeling satisfied. But I am not sure if I am able to work more or be more focused as trial has been too short.

I tried to masturbate. After getting it up and working on it, I just felt it is not worth of effort and gave up. And I don't miss anything. Am I different now? No, it is still the same me. Sexuality has never been integral part of me. I don't miss my libido. I just don't care. Weird.

Is that it? Am I eunuch now? Actually I did expect much greater changes, I would notice every minute. While about sex every normal man would think once every 6 minutes. Or was it more often? I don't think that much about being eunuch.

But again, it has been only 2 weeks. And it is not surgical.

A few comments, but a caveat. The greatest portion of my knowledge of hormones and blockers comes from experience running support groups for M2F (male to female) transsexuals, most of whom were taking both blockers and estrogen, but I have met a number who, for whatever reason, occupational, family or possibly they were really m2eunuch instead of M2F, couldn't afford the feminization of estrogen, but took blockers to decrease maleness. And at support groups one of the favorite topics is hormone regimens and the effect thereof.

One. Two weeks is a very short period to experiment with these drugs. You may get a quick taste of some of the effects, but that is too short a time for your endocrine system to settle down to a stable new lower level. Your letter seems to make the assumption that your T levels vary inversely simply with the blood levels of the blocker. This is only part of the story. Let me draw an analogy to explain. Your hormone system functions like a heating/air conditioning system in a large building, with lots of rooms, halls, dead ends etc., with one large furnace (the testicles) and several space heaters (adrenal glands and fat cells) to provide supplementary heat(testosterone) and the system has considerable lag built in so that it overshoots the desired levels. If you introduce a mass of cold air into the system, the thermostat will turn up the furnace to pump more heat into the system till the temperature rises above its original point. Then the furnace turns off and the temp falls. Likewise if you take androcur, your T levels will fall, your body's hormone thermostat, located mostly in your pituitary and hypothalamus gland, will act to maintain a constant hormonal balance in your body by telling your testes to up the T production. Your T levels will rise often higher than they started, then as T production drops blood levels drop. Were you to graph blood T levels after a dose of T blocker, it would resemble a sine wave varying about a slowly decreasing level. To dampen those swings (which can be extreme) most doctors require new trans patients to ramp the dosage slowly, usually at least over a month and sometimes more. A week taking 1/4 the full dose, then a week each at 1/2, and 3/4 before starting full dose. Trans women are often very impatient and want boobs yesterday, so they often shorten this but seldom to less than two weeks. While ramping up over two days as you did is better than starting with full dose, its still a brutally sudden jolt to your hormone system. While ramping slowly will not eliminate the fatigue you talk about, it will minimize it, particularly if you maintain a vigorous exercise or work program while ramping up, and will reduce the likelihood of violent emotional swings that can go w/ hormonal swings.

Secondly, hormones are some of the most potent placebos known to man. They are so powerful that I have met a couple of trans women who claimed they affected them even before they actually started taking them, that just the decision to take hormones affected their T levels. The way you approached your test, knowing the effects you were expecting, and constantly monitoring yourself for those effects sets yourself for a huge placebo effect. In such a short test, it is almost impossible to separate the effects of the drug, from the effects of your expectations. If you expect orgasm to be harder to reach, you will have that effect, even if you were actually taking a sugar pill.

So you have had some brief glimpses of the effects of castration, but to really feel what it will be like is going to take a longer trial, probably at least 3 - 4 months. Are you financially able to travel to a place that androcur can be shipped. I have no knowledge of how closely your country examines packages shipped into the country, but you might be able to get a friend in another country get the drugs, repackaging them and send them to you. Or you might check if it is any easier to get spiro in your country. Though is is a weaker anti-androgen than androcur, from the evidence of hundreds of T-girls, it is sufficient.

Transward

Transward, thanx for lenghty post! I am aware of all the effects you described, only about this placebo effect I hear first time. I think I've felt placebo effect to some degree, regarding morning erections.

I agree that 2 weeks is too short time. But it is the opportunity I decided to use. I had only 30x50mg of Androcur and wanted to get maximum out if it.

I was surprised about my emotional stability. I was expecting depressions and sudden mood swings. But there was almost none. Also tiredness and weakness has become less and less serious and impotence increased over time despite dosage decrease.

The test period

erikboy (imported) wrote: Fri Aug 24, 2012 1:53 am was too short and inconclusive.

But it was a good experience anyway.

I am not MtoF. I am rather MtoE.

what I will do next, I will wait and see how things will return to "normal".

According to calculations there is still some free androcur in my system. As a

erikboy (imported) wrote: Wed Aug 22, 2012 3:34 pm ndrocur acts in many different ways,

I am witnessing them. For example, today I had first serious hot flashes. As Androcur is a mild progesterone like hormone by itself and there are other precursor hormones accumulated makes my endocrine system think that there is enough T in my system and does not force testicles to produce more. That should be the reason, why high doses of androcur did not cause strong hot flashes. As it is now leaving my system, my endocrine system wakes up and rings alarms. But as androcur is still blocking T receptors for several more days, it is expected to have hot flashes for more days coming.

Today I tried to masturbate for 30-40 minutes, but gave it up. It didn't get that hard even. Very funny. I just didn't care and continued with other activities. I wasn't unhappy at all.

today I had to do some hard work and weakness is really annoying. Atherwise I didn't feel any different. It is still the same me.

I am continuing to have hot flashes. There should be no free Androcur left in my system by now. Only one that remains, is accumulated in T-receptors.

I noticed that I sweat different and smell is different. Not so oily sweat. Yesturday I met an older man, and he smelled the same, so I knew that his T-levels are low naturally or he is having problems with his prostate. There were other indications of low T too. funny, to recognize others with low-T.

I did a lot of physical work yesturday and my muscles are all in pain. I am weak Which is unusual, as I don't get muscle pains that easy.

No erections or orgasms for more than 3 days. Last 2 days I just have forgotten to try or considered that task to exhausting

So far so good.

I think I start to feel T returning to my system.

I feel being agitated. slightly. It feels like T being switched back on in a matter of half day. I started to notice some impulses in me, that usually lead to sexual thoughts. These impulses happen with less intervals. I didn't expect it to happen so abrupt.

But until now I haven't had spontaneous erections for 10 days and I haven't masturbated for like 5 days. Just because there is no desire. Few attempts have failed to achieve orgasm. Yesturday it didn't get properly hard, before I gave up.

It is interesting to monitor and feel the differences with and without T.

Thats all by now.