fvschia01 (imported) wrote: Tue Nov 09, 2021 11:45 pm Wow! Very jealous of your 1 incher. Has it always been that size or have you experienced shrinkage?

At me all this occurred more simply and at once, any "shrinkage" .

fvschia01 (imported) wrote: Tue Nov 09, 2021 10:15 pm Hey Stevenator, I’ve seen your posts around here a few times. I personally tried tagamet dosed at 1000mg/day for about 10 days and noticed little to no difference, however I understand that may not have been enough time. Is there any chance it may have had an enhanced effect on you due to a lack of erections? I’m waiting to receive some dutasteride to use in conjunction with tagamet and a small cage to prevent erections as much as possible and hopefully enhance its effect.

I used 1000 mg per day, taken all at once, every day, for about 8-10 weeks. I permanently lost about 2 inches when flaccid. Still the same size as before when able to erect. So partially successful.

kristoff wrote: Wed Nov 10, 2021 11:45 am I used 1000 mg per day, taken all at once, every day, for about 8-10 weeks. I permanently lost about 2 inches when flaccid. Still the same size as before when able to erect. So partially successful.

Cheers for the reply. I had also seen you on one of the threads regarding shrinking however I thought I remembered you not having much success with it. Probably means I had seen a post from earlier on before you started seeing results.

My results were from numerous dosing periods. I should say the first 2-3 times I took it, I was unaware of that side-effect. I took it to accompany my phytoestrogen program to grow breasts, as a 1,000mg program of Tagamet will also release prolactin. I found out the [hard] way that it also attacks your balls.

The first three times I was alarmed at how I noticed it shrinking. I’d quit, and several months later, and try again. I kept noticing the same results. Everything kept shrinking. By the third time, I had not recovered any size, so I just started a regular program. I’d buy a two-pack of 60 count 200mg Cimetidine, and I’d take them until they were gone.

There are numerous medical research articles available in relation to Cimetidine (Tagamet) and erectile dysfunction, testicles, Leydig cells, testosterone, etc. Just vary the search terms and you’ll get results.

Basically the stuff causes the Leydig cells (sperm/testosterone factory) to shrink. The one term that always stiuck out to me was, “it causes a reduction in sex organ weights”. Medical terminology to say it shrinks your package.

I was on high dose phytoestrogens for 4.5 years. I’ve been on HRT for 1.5 years. I have zero desire to transition, so thankfully I’ve experienced no facial feminization, but so far I’ve got a nice healthy rack. It’s not near as big as I’d like it to be though. I do love myboobs.

But, I don’t know how much size reduction is attributed to solely Cimetidine. I do know the medical research papers said it would happen. I took it when I was taking Pueraria Mirifica, and while PM gave me a slow reduction in size, the dedicated program of Cimetidine gave me accelerated shrinkage.

I can only assume I’ve “bottomed-out” at the baseline, but when I started all this I had a nice fat healthy 7+ inch dick with billiard ball sized nuts. I had big balls. Now, I’m probably 3 inches hard and an inch thick. It’s small. Nuts are the size of large grapes.

YMMV. Good Luck.

Stevenator (imported) wrote: Wed Nov 10, 2021 7:23 pm There are numerous medical research articles available in relation to Cimetidine (Tagamet) and erectile dysfunction, testicles, Leydig cells, testosterone, etc. Just vary the search terms and you’ll get results.

Thanks for getting back to me. To be honest the root of my skepticism is in part due to some of these studies. Firstly and mostly importantly, the dosage given to the rats being studied are much higher than anything we would be using, typically ranging from 20mg/kg/day (equivalent to 1400mg/day in a 70kg human) to 250mg/kg/day (equivalent to 17500mg/day in a 70kg human), which would impact the hypothetical influence of cimetidine on the weight of reproductive organs. Additionally, (and this is mentioned in this more recent study: https://www.spandidos-publications.com/ ... t=fulltext), the cimetidine in these studies is usually administered via intraperitoneal injection (basically injecting directly into the abdomen) which results in a much higher rate of absorption of the drug when compared to oral administration. Finally, the only unanimous effects of the drug seem to be that it decreases the quality/quantity of the sperm via the apoptosis of the Leydig cells, and some alterations to hormonal function. The changes to weight of reproductive organs is somewhat contested as the studies have contradictory results (the most recent one which I linked previously saw insignificant changes to weight), and don't measure changes in size/weight of the penis (as they should, it's not what's being studied here).

I hope you understand my skepticism considering these factors. At least in humans the anecdotes seem to be promising for my goals, seeing as a few of the members here have seen success using it. I will likely try at least one more time while dosing it on a longer term basis, in conjunction with something that will reduce the occurrence of my erections. Hopefully that'll help. Thanks again for your response.

The human equivalent doses I saw listed were 800-1600mg, with anything above 1,600mg being at risk for liver damage. Some studies were for rats and some for humans. They all basically pointed to the same results. I hope you find what you’re looking for.

Stevenator, how long were those dosing periods in that first 2-3 times? Was this sustained over a period of weeks or months when you would take the cimetidine and then stop? Thanks for sharing this.

Probably only a week. The stuff is fast acting. I was alarmed at how fast it happened, so I immediately quit. The 2nd dosing experiment was about a year after the first, and same thing happened. I immediately quit again. After about 3-4 months I still had not recovered any size, and I was steadily losing size from the phytoestrogens, I just said fuck-it and started a steady dosing program for 6-9 months, with re-ordering breaks in-between.

I’m probably three inches hard right now. I went on a strenuous fall color trail hike yesterday, and exercise makes it collapse upon itself. I look like a nullo with a nub when it’s at its smallest.

I can’t believe what I’ve done to myself, but what’s done is done.

Flaccid I am usually less than an inch and frequently have it more in me than out of me, hard I am a bit over 5 inches. I have considered intentionally shrinking but don't like the idea of a one way street...

Stevenator (imported) wrote: Fri Nov 12, 2021 4:08 pm Probably only a week. The stuff is fast acting. I was alarmed at how fast it happened, so I immediately quit. The 2nd dosing experiment was about a year after the first, and same thing happened. I immediately quit again. After about 3-4 months I still had not recovered any size, and I was steadily losing size from the phytoestrogens, I just said fuck-it and started a steady dosing program for 6-9 months, with re-ordering breaks in-between.

I’m probably three inches hard right now. I went on a strenuous fall color trail hike yesterday, and exercise makes it collapse upon itself. I look like a nullo with a nub when it’s at its smallest.

I can’t believe what I’ve done to myself, but what’s done is done.

I think what you've done is amazing, both from the shrinkage and from the breast development. Kudos!