About Chemical Castration - Read This First

[Rocket Number Nine (imported)]

It's been a couple months but, IMO bicalutamide is not the way to go if you're going for a "trial run" on castration. As the above poster said, you still have some testosterone brain-feels on it.

I've used spironolactone and cyproterone myself. Cyproterone definitely feels better to be on, granted it is more harsh on the liver so if you're on it for long periods you'll want to get tested and such. Spironolactone works but it has some rather annoying side effects, which can be outright harsh. I actually was getting heart palpitations from spironolactone because it lowered my blood pressure too much. If you've got high blood pressure though, I imagine it might be the way to go for you, considering its original purpose is as a blood pressure medication and diuretic and testosterone blocking and suppression is merely a side-effect of it.

Bicalutamide is also much more expensive than cyproterone and spironolactone. This probably isn't an issue, but rather just something to consider. It's also much harder to look up information on bicalutamide than it is to find info on cyproterone or spironolactone or other antiandrogens out there, because bicalutamide is simply used less. If you're going to be doing antiandrogens without medical supervision it would be most wise to pick an antiandrogen that is more well-known and has more information, to help you not mess up with it.

[Wolfboy_ (imported)]

I am also very interested in chemical castration to try it before surgery.

Whar medicaments would you recommend, and where can i buy it here in Germany?

The only licensed substance in Gernany for the purpose of cutting down sexual drive and hypersexuality in men is Cyproteron. It comes in pills (Androcur) and injectible substance (Androcur depot) and it has to be prescribed.

[erikboy (imported)]

Androcur is no perfect chemcastration drug. But it is among cheapest and more affordable drugs. These side effects are probaly reason, why it is not used on children with early puberty. Instead triptorelin is used. I think I plan to go from Androcur to Triptorelin, to see and feel the difference. I am currently on 100mg Androcur.

[michieboy (imported)]

Are there additional negative aspects to having both the chemical castration and the surgical castration? Due to the return of prostate cancer, i will be starting with hormone therapy in July, but want my long-hated testicles to be surgically removed as soon as is feasible. I'm just wondering if having both doubles the chances of getting diabetes, osteoporosis, etc.

[whitemoustache (imported)]

There's a positive aspect to being on a dose of Lupron eight times stronger than last time. Razors last longer because one's beard has softened.

[BillyBlogs (imported)]

I have decided to take your advice.

Where do I start though?

To have a trial run. exactly where do I get the medicine? Online? Pharmacy? I am from Sydney Australia so what would be the best and safest way to go?

What drug is the most appropriate to turn off my libido?

HI, I'm just up the road from you, so as to speak. How have things gone for you so far?

[Castor (imported)]

I would like to revive this old thread. After my surgical castration has been approved, I would like to start with a chemical one first to gradually reduce the testosterone level. I am scheduled to meet with an endocrinologist next week for this. Androcur is disreputable because of damage to the liver, suspected of causing cancer, and causing depression. Alternatives would be Casodex. Who has experience to reduce the testosterone level with other means than Androcur?

[WheelyCurious]

I would like to revive this old thread. After my surgical castration has been approved, I would like to start with a chemical one first to gradually reduce the testosterone level. I am scheduled to meet with an endocrinologist next week for this. Androcur is disreputable because of damage to the liver, suspected of causing cancer, and causing depression. Alternatives would be Casodex. Who has experience to reduce the testosterone level with other means than Androcur?

No info on Casodex. Androcur is not FDA approved so not an option for prescription in the US. My doc put me on Lupron which usually comes as an injection every 30 or 90 days. I was starting with a low T-level (about 150ng/dl) and had so little feeling that anything had changed that I thought it wasn't working. It was, as my next test was <12ng, meaning the test couldn't detect any.

Supposedly Lupron has relatively little in the way of bad side effects, and is one of the drugs that docs like for prostate cancer patients. W/o going back to look at my notes, my recollection is that it works by over stimulating the part of the cycle that drives T production, which causes it to shut down. As a result the T-level may actually go UP for the first couple of weeks when starting it, and then it will drop rapidly.

I used it for about 4 months and have since stopped, but am on E which supposedly will keep the testicles shut down, although the adrenals may start back up to some degree. I was happy with the results.

However I'm not sure there is a chemical that will 'gradually reduce' the T level, most all of the drugs I've seen discussed here are more or less switches that shut down the production, with the T level dropping fairly soon after as your body naturally eliminates it.

WheelyCurious

[Castor (imported)]

However I'm not sure there is a chemical that will 'gradually reduce' the T level, most all of the drugs I've seen discussed here are more or less switches that shut down the production, with the T level dropping fairly soon after as your body naturally eliminates it.

Thank you for the reply. I definitely do not want to go without artificial testosterone after my surgical castration. That's why I would be interested in the possibilities of adjusting the T level very individually and not by injections, but in tablet form. So basically I'm interested in a test run of what it would be like to be surgically castrated and reintroduce some artificial testosterone. However, I have already thought that this could be difficult ...

P.S.: Androcur 10 is said to have produced this effect, but because of the significant negative side effects, I obviously don't want to take that.

[WheelyCurious]

Well you could shut down T production and then add supplemental back in, but you'd need to choose the right drug... Some just shut down production, but don't touch the receptors (which is what you want) so the supplemental would act as you expect. However other drugs also impact the receptors and processing of T, in which case the supplements wouldn't do the right thing. I'm not sure which drugs would be better in that regard, presumably you'd need to discuss this with a cooperative doctor.

I haven't looked, so not sure what is available in tablet form... The topical gels (i.e. Androgel) do allow at least crude adjustments, by varying the number of pumps you do per day, and possibly by getting different brands that have different concentration per pump...

One potential downside of the topicals, is that if you do any sort of intimate contact w/ a partner, child, etc. you need to be careful to avoid 'cross-contamination' where the T that hasn't been absorbed rubs off onto the other person giving them an undesired dose... Allegedly this can even be an issue w/ handling laundry, at least according to the package labeling, though I'm not sure how serious a problem it really is...

WheelyCurious