Just started Paxil

gelding (imported)
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Re: Just started Paxil

Post by gelding (imported) »

Checked the insert literature on Paxil, and severe anxiety is one of the potential risks. Had a partner who tried it and he had a very bad time. Normal people can have abnormal reactions to many drugs that pose no problem for the majority of people. Always read inserts to get informed of the potential adverse reactions and how prevalent those are. When the insert advises to seek medical help for some reactions, do so, at once.
Bagoas (imported)
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Re: Just started Paxil

Post by Bagoas (imported) »

That's certainly paradoxical. Anxiety is what I took Paxil and now take Effexor for. It relieved lifelong problem with anxiety.
ramses (imported)
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Re: Just started Paxil

Post by ramses (imported) »

most anti depressants act by increasing the amount of seratonin or dopamine OR both. If your have naturally high levels of these neurotransmitters (or your depression/illness isn't really caused from low levels of the neurotransmitters, I would suspect that you could have a reaction caused by toxic high levels. Problems often arise because people are started on too high of a dose instead of working up to a healthy maintenence dose.

http://en.wikipedia.org/wiki/Serotonin_syndrome (synopsis)

Serotonin syndrome is a potentially life-threatening adverse drug reaction that may occur following therapeutic drug use, inadvertent interactions between drugs, overdose of particular drugs, or the recreational use of certain drugs. The terms serotonin toxicity or serotonin toxidrome are more accurate as they reflect the fact that it is a form of poisoning.[1][2] Rarely it may also be called serotonin storm, hyperserotonemia, or serotonergic syndrome.

Serotonin syndrome is a consequence of excess serotonergic activity at central nervous system (CNS) and peripheral serotonin receptors. This excess serotonin activity produces a spectrum of specific symptoms including cognitive effects, autonomic effects, and somatic effects. The symptoms may range from barely perceptible to fatal.[3] Numerous drugs and drug combinations have been reported to produce serotonin syndrome.

Diagnosis of serotonin syndrome includes observing the symptoms produced and a thorough investigation of the patient's history. The syndrome has a characteristic picture but can be mistaken for other illneses in some patients, particularly those with neuroleptic malignant syndrome. Treatment consists of discontinuing medications which may contribute and in moderate to severe cases administering a serotonin antagonist. An important adjunct treatment includes controlling agitation with benzodiazepine sedation. The high profile case of Libby Zion, who died from serotonin syndrome, resulted in changes to graduate medical education in the United States.

[edit] Signs and symptoms

Symptom onset is usually rapid, often occurring within minutes after self-poisoning or a change in medication. Serotonin syndrome encompasses a wide range of clinical findings. Mild symptoms may only consist of tachycardia, shivering, diaphoresis (sweating), mydriasis (dilated pupils), myoclonus (intermittent tremor or twitching), as well as overresponsive reflexes.[3] Moderate intoxication includes additional abnormalities such as hyperactive bowel sounds, hypertension and hyperthermia; a temperature as high as 40 °C (104 °F) is common in moderate intoxication. The overactive reflexes and clonus in moderate cases may be greater in the lower limbs than in the upper limbs. Mental status changes include hypervigilance and agitation.[3] Severe symptoms include severe hypertension and tachycardia that may lead to shock. Severe cases often have agitated delirium as well as muscular rigidity and high muscular tension. Temperature may rise to above 41.1 °C (106.0 °F) in life-threatening cases. Other abnormalities include metabolic acidosis, rhabdomyolysis, seizures, renal failure, and disseminated intravascular coagulation, these effects usually arise as a consequence of hyperthermia.[3]

The symptoms are often described as a clinical triad of abnormalities:[3][4]

Cognitive effects: mental confusion, hypomania, hallucinations, agitation, headache, coma.

Autonomic effects: shivering, sweating, hyperthermia, hypertension, tachycardia, nausea, diarrhea.

Somatic effects: myoclonus (muscle twitching), hyperreflexia (manifested by clonus), tremor.
gelding (imported)
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Re: Just started Paxil

Post by gelding (imported) »

While anxiety is what Paxil may be prescribed to combat, severe anxiety is one of the known side-effects, and the medication insert advises to stop the medication immediately.

Most physicians use handy reference materials to prescribe medications, and they go by the most-prescribed route without going into in-depth lab testing to determine contraindications unless or until there is a problem with the prescribed medication. Even then, the physician may prescribe a similar medication such as Elavil instead of Paxil, and if that produces the same adverse reaction, try something else.

It is a very rare physician who will follow diligently into in-depth labs unless something comes up that points to serious conditions. You may need to take medical information you learn about yourself to your physician and see if that moves the physician to take further action.
Solaris (imported)
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Re: Just started Paxil

Post by Solaris (imported) »

I am taking 20 mg of Paroxetine or Paxil per day, and masturbation and ejaculation have now ceased. I am also taking 100 micrograms of Ethinylestradiol per day, which is feminizing my mind and body. Both medications have been prescribed by a doctor who is supervising me while I am on them.

I have gained fourteen pounds in weight, but this is not a problem for me as I was starting from a very low weight.

You may have to be patient and persistent, and work cooperatively with your doctor to make sure that you get the very best for yourself, according to your needs. But if it is what you really want, then you will get there in the end.

Good Luck!
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