A most interesting article which is more proof that Transexualism is "medical" and not a kink or a choice.
http://news.bbc.co.uk/2/hi/health/7689007.stm
"proving" transexualism?"
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mrt (imported)
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ramses (imported)
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Re: "proving" transexualism?"
Text to the afore mentioned article submitted by MrT:
Male transsexual gene link found
Australian researchers have identified a significant link between a gene involved in testosterone action and male transsexualism.
DNA analysis from 112 male-to-female transsexual volunteers showed they were more likely to have a longer version of the androgen receptor gene.
The genetic difference may cause weaker testosterone signals, the team reported in Biological Psychiatry.
However, other genes are also likely to play a part, they stressed.
Increasingly, biological factors are being implicated in gender identity.
There is a social stigma that transsexualism is simply a lifestyle choice, however our findings support a biological basis of how gender identity develops
Professor Vincent Harley, researcher
One study has shown that certain brain structures in male-to-female transsexual people are more "female like".
In the latest study, researchers looked for potential differences in three genes known to be involved in sex development - coding for the androgen receptor, the oestrogen receptor and an enzyme which converts testosterone to oestrogen.
Comparison of the DNA from the male to female transsexual participants with 258 controls showed a significant link with a long version of the androgen receptor gene and transsexualism.
Testosterone
It is known that longer versions of the androgen receptor gene are associated with less efficient testosterone signalling.
This reduced action of the male sex hormone may have an effect on gender development in the womb, the researchers speculated.
"We think that these genetic differences might reduce testosterone action and under masculinise the brain during foetal development," said researcher Lauren Hare from Prince Henry's Institute of Medical Research.
Co-author Professor Vincent Harley added: "There is a social stigma that transsexualism is simply a lifestyle choice, however our findings support a biological basis of how gender identity develops."
Although this is the largest genetic study of transsexualism to date, the researchers now plan to see if the results can be replicated in a larger population.
Terry Reed from the Gender Identity Research and Education Society said she was convinced of a biological basis to transsexualism.
"This study appears to reinforce earlier studies which have indicated that, in some trans people, there may be a genetic trigger to the development of an atypical gender identity.
"However, it may be just one of several routes and, although it seems extremely likely that a biological element will always be present in the aetiology of transsexualism, it's unlikely that developmental pathways will be the same in all individuals."
Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/h ... 689007.stm
Published: 2008/10/26 13:01:09 GMT
© BBC MMVIII
Male transsexual gene link found
Australian researchers have identified a significant link between a gene involved in testosterone action and male transsexualism.
DNA analysis from 112 male-to-female transsexual volunteers showed they were more likely to have a longer version of the androgen receptor gene.
The genetic difference may cause weaker testosterone signals, the team reported in Biological Psychiatry.
However, other genes are also likely to play a part, they stressed.
Increasingly, biological factors are being implicated in gender identity.
There is a social stigma that transsexualism is simply a lifestyle choice, however our findings support a biological basis of how gender identity develops
Professor Vincent Harley, researcher
One study has shown that certain brain structures in male-to-female transsexual people are more "female like".
In the latest study, researchers looked for potential differences in three genes known to be involved in sex development - coding for the androgen receptor, the oestrogen receptor and an enzyme which converts testosterone to oestrogen.
Comparison of the DNA from the male to female transsexual participants with 258 controls showed a significant link with a long version of the androgen receptor gene and transsexualism.
Testosterone
It is known that longer versions of the androgen receptor gene are associated with less efficient testosterone signalling.
This reduced action of the male sex hormone may have an effect on gender development in the womb, the researchers speculated.
"We think that these genetic differences might reduce testosterone action and under masculinise the brain during foetal development," said researcher Lauren Hare from Prince Henry's Institute of Medical Research.
Co-author Professor Vincent Harley added: "There is a social stigma that transsexualism is simply a lifestyle choice, however our findings support a biological basis of how gender identity develops."
Although this is the largest genetic study of transsexualism to date, the researchers now plan to see if the results can be replicated in a larger population.
Terry Reed from the Gender Identity Research and Education Society said she was convinced of a biological basis to transsexualism.
"This study appears to reinforce earlier studies which have indicated that, in some trans people, there may be a genetic trigger to the development of an atypical gender identity.
"However, it may be just one of several routes and, although it seems extremely likely that a biological element will always be present in the aetiology of transsexualism, it's unlikely that developmental pathways will be the same in all individuals."
Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/h ... 689007.stm
Published: 2008/10/26 13:01:09 GMT
© BBC MMVIII
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OneBallBoi (imported)
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Re: "proving" transexualism?"
I am so sure that someday we will prove that Homosexuality is a Gene or something. Heterosexuals and Homophobics, just do not understand. This unique desire inside that makes you repelled towards the opposite sex. I just do not trust my opposite sex. I feel they are munipulative and controlling. I think my early childhood had a lot to do with indoctrinating me with the feeling that they can not be trusted. i could never have any intimacy with the opposite sex. It is so repelling to me. There has to be a gene or inbalance of some some chemical that creates this. Someday we will know.
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calmeilles (imported)
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Re: "proving" transexualism?"
You think there is a gene... yet ascribe your feelings to experience.
Personally I suspect that there is a variably strong heritable predilection to bisexuality. How that is expressed depends on the means of expression available in any given culture and the individual's balance between the strength of the urge and the pressures against it.
So strong conditioning may force you one way. A building self confidence may allow you the same path for very different reasons. There is and I doubt there ever will be any single or simple answer.
Personally I suspect that there is a variably strong heritable predilection to bisexuality. How that is expressed depends on the means of expression available in any given culture and the individual's balance between the strength of the urge and the pressures against it.
So strong conditioning may force you one way. A building self confidence may allow you the same path for very different reasons. There is and I doubt there ever will be any single or simple answer.