A way to minimize it

[thepenectomised (imported)]

25 mg of Spironolactone is not going to do much of anything for you. The usual dosage for M2F is 200 mg per day, and it does work at that level.

Are you sure about the 200mg?

A person I know is given 25mg per day to cope with his hypertension. If 25mg does this, I wonder how low the blood pressure of TS pple are, especially since most have normal BP to begin with.

[Christina (imported)]

Are you sure about the 200mg?

A person I know is given 25mg per day to cope with his hypertension. If 25mg does this, I wonder how low the blood pressure of TS pple are, especially since most have normal BP to begin with.

Yes, I'm quite sure. I've been on that dosage for almost 6 years. Some even take up to 300 mgs per day, and a group in Canada I believe, was taking up to 600 mg a day.

It's also given to natal females in that quantity for Histurism (sp), for excess hair growth.

[fami (imported)]

Are you sure about the 200mg?

A person I know is given 25mg per day to cope with his hypertension. If 25mg does this, I wonder how low the blood pressure of TS pple are, especially since most have normal BP to begin with.

Taken from http://www.globaldrug.tv/category.asp?CtgID=1903

Sometimes 100 mg of spironolactone may be sufficient, but 200–300 mg is a more typical dose. The Vancouver group uses up to 600 mg daily, apparently without problems. Spironolactone is fairly inexpensive, is readily available, and is usually quite well tolerated. In my opinion, it should be regarded as the anti-androgen of choice for most patients. Cyproterone is actually a progestin (see below), but it is used primarily for its anti-androgenic effects and only secondarily for its progestational effects. It is not available in the US, but is popular elsewhere. One disadvantage of cyproterone is that it counteracts some of the desirable effects of estrogen on blood lipids. Cyproterone, when used in combination with estrogen, may also share some of the increased risks associated with the synthetic progestin medroxyprogesterone when so used (see below).

It also says that Progestins like provera / Depo-Provera are not really necesary. It says Progestins are most often given in an attempt to increase breast development. Based on limited anecdotal evidence, they think think that improved breast development sometimes can occur, but that the effects are usually not very significant. Is this true?.

[thepenectomised (imported)]

Yes, I'm quite sure. I've been on that dosage for almost 6 years. Some even take up to 300 mgs per day, and a group in Canada I believe, was taking up to 600 mg a day.

It's also given to natal females in that quantity for Histurism (sp), for excess hair growth.

Do you take any other thing to incease back blood pressure then? Indeed, reducing of BP will take place even in low doses and there is a linear effect in respect of the dosage accrding to another research.

Have you got your BP checked?

:

http://www.docguide.com/news/content.ns ... B4006DD388

The addition of low-dose spironolactone to a multi-drug regimen for treatment-resistant hypertension can induce significant blood pressure reductions, even in patients who have no evidence of primary hyperaldosteronism (PA), according to results reported here September 25th at the American Heart Association's 57th Annual Conference on High Blood Pressure Research.

Dr. Mohammad A Zaman, University of Alabama, Birmingham, Alabama, United States, who presented the study, said that adding low dose spironolactone (12.5 to 25 mg/day) for 6 months decreased systolic blood pressure by an average of 22 mm Hg and diastolic blood pressure by an average of 11 mm Hg. Moreover, "patients without PA had a greater reduction than patients with PA," he said. He noted that the systolic reductions were greatest in black subjects, whose levels decreased by an average of 23 mm Hg.

[Christina (imported)]

Do you take any other thing to incease back blood pressure then? Indeed, reducing of BP will take place even in low doses and there is a linear effect in respect of the dosage accrding to another research.

Have you got your BP checked?

No, I don't take anything else to increase my BP. At one time I did have mild hypertension and my BP was a bit high (low 150's over the upper 70's). I've had my BP checked at least a dozen times this year alone and it's has ranged from 116/64 to about 124/82, well within the norm.

[Robby (imported)]

Have you got your BP checked?

//www.docguide.com/news/content.nsf/news/ ... B4006DD388

WASHINGTON, DC -- October 3, 2003

The addition of low-dose spironolactone to a multi-drug regimen for treatment-resistant hypertension can induce significant blood pressure reductions, even in patients who have no evidence of primary hyperaldosteronism (PA), according to results reported here September 25th at the American Heart Association's 57th Annual Conference on High Blood Pressure Research.

Dr. Mohammad A Zaman, University of Alabama, Birmingham, Alabama, United States, who presented the study, said that adding low dose spironolactone (12.5 to 25 mg/day) for 6 months decreased systolic blood pressure by an average of 22 mm Hg and diastolic blood pressure by an average of 11 mm Hg. Moreover, "patients without PA had a greater reduction than patients with PA," he said. He noted that the systolic reductions were greatest in black subjects, whose levels decreased by an average of 23 mm Hg.

I suffer from Hypertension and the above article is a great find. My blood pressure issue goes back to when I was a young teen. Genes you know, what can you do?...

Thanks for posting the above link.