A recent Australian study has this to say:
http://www.theage.com.au/articles/2003/ ... click=true
The inreased risk of coronary diseases in men as opposed to women has been known for years. What curious is that this study collaborate what was a common assumption among medics 10-20 years ago, untill viagra and steroids entered the world market, and "ridiculed" the androgen-link.
Androgens linked to heart disease
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evirated (imported)
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Re: Androgens linked to heart disease
It appear you have to register to read the article. Here's a cached link:
http://www.google.com/search?q=cache:Rkg1fSJSVE8J:
Testosterone makes the heart fail faster
By Judy Skatssoon, Lucy Beaumont
September 17, 2003
Men face a greater risk of heart disease than women because of the very thing that makes them men, according to a world-first Australian study showing male sex hormones promote coronary disease.
It is well known that men develop heart disease earlier than women, experience more severe heart disease and are more likely to die from heart disease than women.
However, until now the reasons for this have been unclear.
The study by researchers at Sydney's Royal Prince Alfred Hospital is the first to provide scientific evidence that male sex hormones such as testosterone - known as androgens - activate genes involved in the development of heart disease.
However, the androgens did not have the same effect in women.
"We were able to see that male sex hormones activated 30 genes that stimulate coronary disease in men," the study's author, Martin Ng, said.
The two-year study extracted cells involved in artery hardening from five men and five women all aged under 35 with no signs of heart disease.
Researchers then added androgens to the cells in laboratory experiments.
"We isolated a cell that is involved at the earliest stage of coronary artery disease in men and women and we exposed these cells to the male sex hormone, androgen," Dr Ng said.
"In a very surprising finding, when we used the same male sex hormones in women nothing happened.
"This is a very striking biological finding that may help us explain why it is that men are much more susceptible to coronary disease than women."
Male genes were expressed three to five times more than normal by cells to which androgens had been added.
The study was given express online publication by the Journal of the American College of Cardiology because of its significance for research and treatment development.
The Austin Hospital's senior cardiologist, David Hare, said the findings showed there were gender differences in cell structure, not just in testosterone levels.
"It's not just related to men having more testosterone but men have a different sort of cell type to women," Professor Hare said. "Therefore their response to testosterone is quite different."
Dr Ng said women did not respond to testosterone in the same way as men because they only had a quarter of the androgen receptors.
The discovery of the role of testosterone could result in more gender-specific therapies for heart disease patients and more aggressive education and awareness campaigns targeting men.
"The suggestion would be that simply altering hormone levels in males or females wouldn't necessarily alter disease rates," Professor Hare said.
Heart disease kills five times more men than women in the 35-65 age group worldwide, and even teenage boys and men in their early 20s have higher levels of cholesterol than young women.
"It underscores what a strong risk factor being a man is for coronary heart disease," Dr Ng said.
He urged men over 35 to have regular medical checks and monitor their blood pressure and cholesterol.
Professor Hare said the Austin Hospital would soon begin a study to measure the effects of androgen replacement therapy.
http://www.google.com/search?q=cache:Rkg1fSJSVE8J:
%3Ffrom%3Dstoryrhs+%22Judy+Skats soon,+Lucy+Beaumont&hl=nnevirated (imported) wrote: Sat Jan 15, 2005 8:18 pm www.theage.com.au/articles/2003/09/16/1 ... 32926.html
Testosterone makes the heart fail faster
By Judy Skatssoon, Lucy Beaumont
September 17, 2003
Men face a greater risk of heart disease than women because of the very thing that makes them men, according to a world-first Australian study showing male sex hormones promote coronary disease.
It is well known that men develop heart disease earlier than women, experience more severe heart disease and are more likely to die from heart disease than women.
However, until now the reasons for this have been unclear.
The study by researchers at Sydney's Royal Prince Alfred Hospital is the first to provide scientific evidence that male sex hormones such as testosterone - known as androgens - activate genes involved in the development of heart disease.
However, the androgens did not have the same effect in women.
"We were able to see that male sex hormones activated 30 genes that stimulate coronary disease in men," the study's author, Martin Ng, said.
The two-year study extracted cells involved in artery hardening from five men and five women all aged under 35 with no signs of heart disease.
Researchers then added androgens to the cells in laboratory experiments.
"We isolated a cell that is involved at the earliest stage of coronary artery disease in men and women and we exposed these cells to the male sex hormone, androgen," Dr Ng said.
"In a very surprising finding, when we used the same male sex hormones in women nothing happened.
"This is a very striking biological finding that may help us explain why it is that men are much more susceptible to coronary disease than women."
Male genes were expressed three to five times more than normal by cells to which androgens had been added.
The study was given express online publication by the Journal of the American College of Cardiology because of its significance for research and treatment development.
The Austin Hospital's senior cardiologist, David Hare, said the findings showed there were gender differences in cell structure, not just in testosterone levels.
"It's not just related to men having more testosterone but men have a different sort of cell type to women," Professor Hare said. "Therefore their response to testosterone is quite different."
Dr Ng said women did not respond to testosterone in the same way as men because they only had a quarter of the androgen receptors.
The discovery of the role of testosterone could result in more gender-specific therapies for heart disease patients and more aggressive education and awareness campaigns targeting men.
"The suggestion would be that simply altering hormone levels in males or females wouldn't necessarily alter disease rates," Professor Hare said.
Heart disease kills five times more men than women in the 35-65 age group worldwide, and even teenage boys and men in their early 20s have higher levels of cholesterol than young women.
"It underscores what a strong risk factor being a man is for coronary heart disease," Dr Ng said.
He urged men over 35 to have regular medical checks and monitor their blood pressure and cholesterol.
Professor Hare said the Austin Hospital would soon begin a study to measure the effects of androgen replacement therapy.
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TheOtherSide (imported)
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Re: Androgens linked to heart disease
And, from the other side....
http://www.gladiatordiet.com/testosterone_study.htm
"No Compelling Evidence" of Prostate Cancer, Heart Disease Risk Found in Study of Testosterone Replacement Therapy
A retrospective analysis by researchers at Beth Israel Deaconess Medical Center published in The New England Journal of Medicine found no causal relationship between testosterone replacement and prostate cancer or heart disease risk.
The comprehensive review of 72 studies, addresses the current controversy about testosterone replacement therapy and its potential health risks to men. "We reviewed decades of research and found no compelling evidence that testosterone replacement therapy increases the incidence of prostate cancer or cardiovascular disease," said Abraham Morgentaler, MD, a urologist at BIDMC and associate clinical professor at Harvard Medical School. "Although it would be helpful to have data from long-term, large-scale studies, it must also be recognized that there already exists a substantial body of research on the effects of testosterone in men."
Low levels of testosterone affect an estimated 2 to 4 million men in the United States, a condition termed hypogonadism, and the prevalence of this condition increases with age. The symptoms include diminished libido and sense of vitality, erectile dysfunction, reduced muscle mass and bone density, depression, and anemia.
The causes of hypogonadism may be classified as primary, meaning inadequate function of the testes; secondary, inadequate pituitary stimulation of the testes; or a combination of primary and secondary causes, which is common in older men. Testosterone supplementation, in the form of injections, patches, gels and a buccal tablet, is designed to elevate a hypogonadal man's testosterone levels into the normal physiologic range and alleviate symptoms.
"Testosterone is only for men who have symptoms of low testosterone combined with a confirmatory blood test. Testosterone therapy can be beneficial and safe for these men as long as they are appropriately monitored by their physician," says Morgentaler.
It has been known since the 1940's that severe reductions of testosterone can cause shrinkage of metastatic prostate cancer, and therefore there has been a concern that raising testosterone levels might cause growth of any hidden prostate cancers. However, the study by Ernani L. Rhoden, M.D., and Morgentaler found no connection between higher testosterone levels and prostate cancer, nor did they find evidence that testosterone treatment causes prostate cancer.
In fact, they note that prostate cancer becomes more prevalent exactly at the time of a man's life when testosterone levels decline. To date, prospective studies have demonstrated no difference in prostate cancer incidence among hypogonadal men using testosterone therapy compared to men in the general population.
Regarding benign prostatic hyperplasia (BPH), multiple studies have failed to demonstrate consistent exacerbation of voiding symptoms during testosterone supplementation. "The impact of testosterone therapy on benign prostate growth appears to be mild," says Rhoden, "and rarely of clinical significance. However, testosterone therapy should be used cautiously in men with severe urinary symptoms."
Monitoring the prostate during testosterone therapy is mandatory, given the theoretical concern that testosterone treatment may stimulate the growth of an occult cancer. Before and during treatment men should undergo regular evaluation, with a digital examination of the prostate, and a blood test called prostate-specific antigen (PSA). Patients with an abnormal prostate exam or an elevated PSA should undergo a prostate biopsy before initiating testosterone replacement to exclude the possibility that cancer is present. To monitor BPH, they recommend determining a base-line voiding history at the start of treatment and assessing urinary symptoms at follow-up. The belief that testosterone may be a risk factor in cardiovascular disease is based on the observation that more men than women have cardiovascular events and men have higher testosterone levels than women. However, Rhoden and Morgentaler write that few, if any, data support a causal relation between higher testosterone levels and heart disease.
Indeed, several studies suggest that higher testosterone levels may actually have a favorable effect on atherosclerosis and heart disease. Studies of testosterone replacement therapy have not demonstrated an increased incidence of cardiovascular disease, myocardial infarction, stroke, or angina, according to the retrospective analysis.
Rhoden and Morgentaler describe other potential risks or side effects from testosterone replacement therapy as infrequent (acne or oily skin, sleep apnea); rarely of clinical significance (fluid retention); or reversible with cessation of treatment (gynecomastia, testicular atrophy or infertility). Testosterone treatment should be used cautiously or not at all in men with advanced liver disease. Skin reactions are commonly encountered in men being treated with the patch with a low incidence observed with testosterone gel.
And....
http://chealth.canoe.ca/health_news_det ... ws_id=8682
Heart attack linked to low testosterone levels Oct. 6, 2003
Provided by: Sun Media
What caused the sudden heart attack? Ask anyone this question and many would accuse too much cholesterol, chronic stress, smoking, obesity or bad genetics. But what about the role of the male hormone testosterone in causing cardiovascular disease? Is erectile dysfunction (ED) an early warning sign of heart attack? And what can we learn about testosterone treatment from a London Harley St. specialist?
Recently, much has been written about the male menopause (andropause). How decreasing amounts of testosterone contribute to the increasing number of impotent males. But it appears there's more to testosterone than sexual potency.
To find out about this exciting aspect of testosterone, I recently met with Dr. Peter Collins, professor of Clinical Cardiology at the Imperial College of Science and Medicine in London, England, a leading expert on testosterone and coronary heart disease.
Dr. Collins notes that it's been known for years that men are more likely than women to suffer a coronary attack before age 50. Physicians believed that estrogen protects women from this disease, while in males testosterone was the culprit.
FLOW OF BLOOD
However, he believes studies now show this assumption to be wrong. Rather, mounting evidence demonstrates that normal amounts of testosterone help to protect against coronary disease. And that males with low testosterone may be more likely to suffer heart attack.
For instance, Collins' research shows that testosterone increases the flow of blood through coronary arteries by as much as 15% to 20%. This explains why patients suffering from angina (chest pain that occurs during exercise) have been helped by testosterone treatment. In addition to increasing blood flow testosterone also decreases blood cholesterol and fibrinogen, the small particles that help to form blood clots.
Another researcher, Dr. Steven Grover, professor of medicine at McGill University, recently reported that erectile dysfunction may be an early warning signal for cardiovascular disease.
He says, "In approximately 25% of cardiovascular patients the first symptom of cardiovascular disease is that they drop dead." No one would call this an encouraging symptom. All the more reason for finding a sign to indicate an attack is likely to happen.
Dr. Grover's study compared 4,000 men with and without cardiovascular disease. It showed that men with cardiovascular disease had a 54% probability of having ED than those without cardiovascular disease.
He believes this suggests that ED may be an early warning sign that heart disease is present. "If this is the case then doctors would be screening patients for ED, not because they want to probe into their bedroom activities, but rather to determine their risk of cardiovascular disease," he says.
This study by Dr. Grover should not be a surprising finding. A satisfactory sexual response depends on adequate flow of blood into the male organ. And with hardening of the arteries, diminished blood flow isn't going to help sexual response.
Testosterone also helps to fight one of this nation's biggest killers. Obese diabetics often develop what is known as insulin resistance. They may have adequate amounts of insulin, but the cells refuse to accept it. It's like having enough gas in the car, but the engine refuses to use it. Testosterone's beneficial effect is increasing the effectiveness of insulin.
While in London, I also met with Dr. Malcolm Carruthers, a distinguished Harley Street pioneer in testosterone treatment. He's treated 1,500 impotent males, those who had lost the tiger-in-the-tank, lacked energy, were depressed and suffering from impotence.
Carruthers sent a strong message about the treatment of andropause patients. He claimed Canadian doctors were fortunate that an oral form of testosterone (Andriol) is available in Canada. But doctors , he says, rely too much on blood testosterone levels in deciding whether or not to treat patients. And that often the correlation between blood levels and symptoms is weak. He believes doctors should trust symptoms more when treating andropause.
During an afternoon at Dr. Carruthers' clinic, several happy males were being treated. One elderly male left with a gleam in his eye. He left no doubt that he would shortly be courting his lady. And in this pursuit, testosterone may also protect him from a heart attack.
What may be happining is that while low levels increase your risks, high (as in higher-than-normal) levels may also increase your risks.
http://www.gladiatordiet.com/testosterone_study.htm
"No Compelling Evidence" of Prostate Cancer, Heart Disease Risk Found in Study of Testosterone Replacement Therapy
A retrospective analysis by researchers at Beth Israel Deaconess Medical Center published in The New England Journal of Medicine found no causal relationship between testosterone replacement and prostate cancer or heart disease risk.
The comprehensive review of 72 studies, addresses the current controversy about testosterone replacement therapy and its potential health risks to men. "We reviewed decades of research and found no compelling evidence that testosterone replacement therapy increases the incidence of prostate cancer or cardiovascular disease," said Abraham Morgentaler, MD, a urologist at BIDMC and associate clinical professor at Harvard Medical School. "Although it would be helpful to have data from long-term, large-scale studies, it must also be recognized that there already exists a substantial body of research on the effects of testosterone in men."
Low levels of testosterone affect an estimated 2 to 4 million men in the United States, a condition termed hypogonadism, and the prevalence of this condition increases with age. The symptoms include diminished libido and sense of vitality, erectile dysfunction, reduced muscle mass and bone density, depression, and anemia.
The causes of hypogonadism may be classified as primary, meaning inadequate function of the testes; secondary, inadequate pituitary stimulation of the testes; or a combination of primary and secondary causes, which is common in older men. Testosterone supplementation, in the form of injections, patches, gels and a buccal tablet, is designed to elevate a hypogonadal man's testosterone levels into the normal physiologic range and alleviate symptoms.
"Testosterone is only for men who have symptoms of low testosterone combined with a confirmatory blood test. Testosterone therapy can be beneficial and safe for these men as long as they are appropriately monitored by their physician," says Morgentaler.
It has been known since the 1940's that severe reductions of testosterone can cause shrinkage of metastatic prostate cancer, and therefore there has been a concern that raising testosterone levels might cause growth of any hidden prostate cancers. However, the study by Ernani L. Rhoden, M.D., and Morgentaler found no connection between higher testosterone levels and prostate cancer, nor did they find evidence that testosterone treatment causes prostate cancer.
In fact, they note that prostate cancer becomes more prevalent exactly at the time of a man's life when testosterone levels decline. To date, prospective studies have demonstrated no difference in prostate cancer incidence among hypogonadal men using testosterone therapy compared to men in the general population.
Regarding benign prostatic hyperplasia (BPH), multiple studies have failed to demonstrate consistent exacerbation of voiding symptoms during testosterone supplementation. "The impact of testosterone therapy on benign prostate growth appears to be mild," says Rhoden, "and rarely of clinical significance. However, testosterone therapy should be used cautiously in men with severe urinary symptoms."
Monitoring the prostate during testosterone therapy is mandatory, given the theoretical concern that testosterone treatment may stimulate the growth of an occult cancer. Before and during treatment men should undergo regular evaluation, with a digital examination of the prostate, and a blood test called prostate-specific antigen (PSA). Patients with an abnormal prostate exam or an elevated PSA should undergo a prostate biopsy before initiating testosterone replacement to exclude the possibility that cancer is present. To monitor BPH, they recommend determining a base-line voiding history at the start of treatment and assessing urinary symptoms at follow-up. The belief that testosterone may be a risk factor in cardiovascular disease is based on the observation that more men than women have cardiovascular events and men have higher testosterone levels than women. However, Rhoden and Morgentaler write that few, if any, data support a causal relation between higher testosterone levels and heart disease.
Indeed, several studies suggest that higher testosterone levels may actually have a favorable effect on atherosclerosis and heart disease. Studies of testosterone replacement therapy have not demonstrated an increased incidence of cardiovascular disease, myocardial infarction, stroke, or angina, according to the retrospective analysis.
Rhoden and Morgentaler describe other potential risks or side effects from testosterone replacement therapy as infrequent (acne or oily skin, sleep apnea); rarely of clinical significance (fluid retention); or reversible with cessation of treatment (gynecomastia, testicular atrophy or infertility). Testosterone treatment should be used cautiously or not at all in men with advanced liver disease. Skin reactions are commonly encountered in men being treated with the patch with a low incidence observed with testosterone gel.
And....
http://chealth.canoe.ca/health_news_det ... ws_id=8682
Heart attack linked to low testosterone levels Oct. 6, 2003
Provided by: Sun Media
What caused the sudden heart attack? Ask anyone this question and many would accuse too much cholesterol, chronic stress, smoking, obesity or bad genetics. But what about the role of the male hormone testosterone in causing cardiovascular disease? Is erectile dysfunction (ED) an early warning sign of heart attack? And what can we learn about testosterone treatment from a London Harley St. specialist?
Recently, much has been written about the male menopause (andropause). How decreasing amounts of testosterone contribute to the increasing number of impotent males. But it appears there's more to testosterone than sexual potency.
To find out about this exciting aspect of testosterone, I recently met with Dr. Peter Collins, professor of Clinical Cardiology at the Imperial College of Science and Medicine in London, England, a leading expert on testosterone and coronary heart disease.
Dr. Collins notes that it's been known for years that men are more likely than women to suffer a coronary attack before age 50. Physicians believed that estrogen protects women from this disease, while in males testosterone was the culprit.
FLOW OF BLOOD
However, he believes studies now show this assumption to be wrong. Rather, mounting evidence demonstrates that normal amounts of testosterone help to protect against coronary disease. And that males with low testosterone may be more likely to suffer heart attack.
For instance, Collins' research shows that testosterone increases the flow of blood through coronary arteries by as much as 15% to 20%. This explains why patients suffering from angina (chest pain that occurs during exercise) have been helped by testosterone treatment. In addition to increasing blood flow testosterone also decreases blood cholesterol and fibrinogen, the small particles that help to form blood clots.
Another researcher, Dr. Steven Grover, professor of medicine at McGill University, recently reported that erectile dysfunction may be an early warning signal for cardiovascular disease.
He says, "In approximately 25% of cardiovascular patients the first symptom of cardiovascular disease is that they drop dead." No one would call this an encouraging symptom. All the more reason for finding a sign to indicate an attack is likely to happen.
Dr. Grover's study compared 4,000 men with and without cardiovascular disease. It showed that men with cardiovascular disease had a 54% probability of having ED than those without cardiovascular disease.
He believes this suggests that ED may be an early warning sign that heart disease is present. "If this is the case then doctors would be screening patients for ED, not because they want to probe into their bedroom activities, but rather to determine their risk of cardiovascular disease," he says.
This study by Dr. Grover should not be a surprising finding. A satisfactory sexual response depends on adequate flow of blood into the male organ. And with hardening of the arteries, diminished blood flow isn't going to help sexual response.
Testosterone also helps to fight one of this nation's biggest killers. Obese diabetics often develop what is known as insulin resistance. They may have adequate amounts of insulin, but the cells refuse to accept it. It's like having enough gas in the car, but the engine refuses to use it. Testosterone's beneficial effect is increasing the effectiveness of insulin.
While in London, I also met with Dr. Malcolm Carruthers, a distinguished Harley Street pioneer in testosterone treatment. He's treated 1,500 impotent males, those who had lost the tiger-in-the-tank, lacked energy, were depressed and suffering from impotence.
Carruthers sent a strong message about the treatment of andropause patients. He claimed Canadian doctors were fortunate that an oral form of testosterone (Andriol) is available in Canada. But doctors , he says, rely too much on blood testosterone levels in deciding whether or not to treat patients. And that often the correlation between blood levels and symptoms is weak. He believes doctors should trust symptoms more when treating andropause.
During an afternoon at Dr. Carruthers' clinic, several happy males were being treated. One elderly male left with a gleam in his eye. He left no doubt that he would shortly be courting his lady. And in this pursuit, testosterone may also protect him from a heart attack.
What may be happining is that while low levels increase your risks, high (as in higher-than-normal) levels may also increase your risks.
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evirated (imported)
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Re: Androgens linked to heart disease
TheOtherSide (imported) wrote: Sat Jan 15, 2005 11:46 pm What may be happining is that while low levels increase your risks, high (as in higher-than-normal) levels may also increase your risks.
Thank you for these quotes. Obviously, little agreement is here between the Australian study and the one's you've posted. Clear logic suggests that both can't be right; someone surely has to be wrong here. In some sense.
You see, in the link I provided, "men" and "testosterone" were clearly treated as a category. Men in their 40's have 4 times more risk of developing coronary diseases than the opposite gender. This is an established fact (as according to worldwide health statistics). All men, on the average. Men with average t-levels, so to say - this same average is enough to cause the increased heart trouble. If the study implied that male hormones activated a whopping 30 genes for heart illness (as is also the case with estrogen and breast cancer), how can one then claim the hormone is at all beneficial for cardiovascular system? Also, there was no mention whatsoever of men with "high t-levels" to qualify for the disease - just men in general.
But let us examine a bit the question of low t-levels, as treated in the links you've provided. In most cases, these are elder (not neccesary old; at least 40 and up) men with lowered t. Usually as a result of aging, or some internal diseases. These are men that all went through puberty and have secondary sexual characteristics present (wich mean they had enough androgens for that). They may or may not have been hypogonadal since youth. These aren't eunuchs. There is a difference between elderly hypogonadal person and an eunuch.
In most such studies there is no second hand information on general health of the participants. How much testosterone these "hypogonadals" had in their youth, and what may be causing the lowered levels, and the risk. Then there is to consider the levels of unbinded dihydrotestosterone, the most powerful variant, wich is more active in bald men. Levels of dihydrotestosterone and binded testosterone are not neccesary related.
http://www.hair-news.com/baldness-heart-risk.shtml
Wich leads to increased risk of heart failure and general decline in stamina (as observed by Napoleon's doctors).
Finally, testosterone is associated with higher blood pressure (a strong risk factor for coronary disease) and cholesterol levels:
"So high blood pressure and high cholesterol lower testosterone, so men with low testosterone are at increased risk for heart attacks."
http://www.drmirkin.com/men/1008.html
I think hereby many look at low testosterone alone; but it is only a symptom of a general decline, and not the cause of it.
How about this: Testosterone -> high cholesterol & blood pressure -> atheroscelrosis & low testosterone!
You can then, to be sure, observe correlance of low testosterone and high cholesterol, but that won't change much of the above.
For instance, you could object why testosterone is dangerous to the prostate when in your 20's, full of androgens, you had no prostate hyperplasy. Then at 50-60, with your t-levels actually DECLINING (ca. 60-70% of previous levels) - BANG! You've got it. You've also got baldness. Why? Because all this is consequences of long term testosterone exposure. You can't just say semi-hypogonadal men get prostate troubles and go bald in older age because of declining testosterone - eunuchs never develop any of this stuff!
Eunuchs live significantly more than intact males, much like females. This is established through numerous research on animals and partly on humans. I had myself done a qucik research on the castrati in the Sistine Chapel, with dates provided by Alberto de Angelis in his "Domenico Mustafa - la capella Sistina e la societa musicale Romana". Some quick results:
Singers category (all sopranis were castrati; all contraltos were falsettists)
Amount Av. lifespan Lowest age at death
Soprano 16 67,81 54 (!)
Contralto 15 65,13 35
Tenor 17 64,76 38
Bass 15 67,33 43
Only 2 of the castrati died before 60, whilst 4-6 of other group.
Now, if testosterone really was that healthy as some claim, the above (and there are much more examples) won't be the case. It is all perfectly in accordance to evolutionary selectionism of expence of one for all (ie. sexual reproduction at a cost of the individual).
http://wcvb-tvhealth.ip2m.com/index.cfm ... e_cat_id=6
"There are a couple of possible explanations for the difference, Wilson says. One is that the male sex hormone testosterone is no help. "In the last 10 or 15 years, there have been studies suggesting that higher levels act as a suppressor of the immune system, so that men have higher levels of parasitic infections," he says."
As here:
http://news.bbc.co.uk/1/hi/health/236488.stm
Now, I know there's a variety of assorted articles on the issue, and many are indeed based on bogus research and partisan arrangements (wich I believe are mostly those in favor of machismo). We all hear that one study finds this, then a few days later, the other comes with opposite results; only to be contradicted by the next. So on and on it goes! But as I had stated my point clearly, I'll stick with the one I've posted. Thanks for the interest, and for reading all this!
BT: IF anyone is interested in the Capella study and a chart of weekly ejaculations of tenors, barytons and basses, I'll gladly post it.
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JeffEunuch (imported)
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Re: Androgens linked to heart disease
Folks,
Keep posting on the contradictory evidence on the impact of testosterone on our bodies. Being gelded myself and also interested in maintaining my overall health, muscle mass and bone density, I'm always keen to learn more. My own doc says that healthy amounts of testosterone are critical to good heart health. I was being treated for hypogonadism prior to seeking to have myself neutered. While my doc stressed the need to limit amounts and cycle treatments to maintain some ability for my testes to generate some level of androgen production autonomously when I still had one testicle, his casual remark on learning I'd had it removed was that he no longer had to be concerned and I could have as much testosterone as I wanted. I've continued ingesting in moderate amounts.
I had my annual physical last month - always recommended for 60+ y.o. guys. It's been 2 years since I had my last PSA blood test to confirm if anything unusual is going on with my prostate gland with testosterone treatment. When I asked whether he was going to ask for the PSA test, he said that the provicial health ministry had recently concluded that it wasn't necessary, as there was no
As usual my blood test this time included HIV and syphillus - both negative. I try to play it pretty safe.
Keep posting on the contradictory evidence on the impact of testosterone on our bodies. Being gelded myself and also interested in maintaining my overall health, muscle mass and bone density, I'm always keen to learn more. My own doc says that healthy amounts of testosterone are critical to good heart health. I was being treated for hypogonadism prior to seeking to have myself neutered. While my doc stressed the need to limit amounts and cycle treatments to maintain some ability for my testes to generate some level of androgen production autonomously when I still had one testicle, his casual remark on learning I'd had it removed was that he no longer had to be concerned and I could have as much testosterone as I wanted. I've continued ingesting in moderate amounts.
I had my annual physical last month - always recommended for 60+ y.o. guys. It's been 2 years since I had my last PSA blood test to confirm if anything unusual is going on with my prostate gland with testosterone treatment. When I asked whether he was going to ask for the PSA test, he said that the provicial health ministry had recently concluded that it wasn't necessary, as there was no
for hypogonadism placed one's prostate gland at greater risk than the average intact male not receiving treatment. Of course, he still did the digital exam through the anus. They still recommend the test if there's any other indications that something's awrye.
As usual my blood test this time included HIV and syphillus - both negative. I try to play it pretty safe.
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evirated (imported)
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Re: Androgens linked to heart disease
Folks,
As usual my blood test this time included HIV
[/quote]
and syphillus - both negative. I try to play it pretty safe.
Hi Jeff!
Regarding prostate cancer, there is some interesting data (I think from about 1940's) on Chinese eunuchs when it comes to prostate. In some the gland was clearly present, while in others it was undetectable. None had detectable cancer. So there's is some individual variation, as well.
[quote="TheOtherSide (imported)" timJeffEunuch (imported) wrote: Sun Jan 16, 2005 8:25 am Keep posting on the contradictory evidence on the impact of testosterone on our bodies. Being gelded myself and also interested in maintaining my overall health, muscle mass and bone density, I'm always keen to learn more. My own doc says that healthy amounts of testosterone are critical to good heart health. I was being treated for hypogonadism prior to seeking to have myself neutered. While my doc stressed the need to limit amounts and cycle treatments to maintain some ability for my testes to generate some level of androgen production autonomously when I still had one testicle, his casual remark on learning I'd had it removed was that he no longer had to be concerned and I could have as much testosterone as I wanted. I've continued ingesting in moderate amounts.
I had my annual physical last month - always recommended for 60+ y.o. guys. It's been 2 years since I had my last PSA blood test to confirm if anything unusual is going on with my prostate gland with testosterone treatment. When I asked whether he was going to ask for the PSA test, he said that the provicial health ministry had recently concluded that it wasn't necessary, as there was no
for hypogonadism placed one's prostate gland at greater risk than the average intact male not receiving treatment. Of course, he still did the digital exam through the anus. They still recommend the test if there's any other indications that something's awrye.JeffEunuch (imported) wrote: Sun Jan 16, 2005 8:25 am e=1105793160]
evidence that testosterone treatment
As usual my blood test this time included HIV
[/quote]
and syphillus - both negative. I try to play it pretty safe.
Hi Jeff!
Regarding prostate cancer, there is some interesting data (I think from about 1940's) on Chinese eunuchs when it comes to prostate. In some the gland was clearly present, while in others it was undetectable. None had detectable cancer. So there's is some individual variation, as well.