prolactin problems and antiandrogens/estrogen

[Frida G Cavic (imported)]

Wow! This is great news. I have not been around much lately. It looks like all is finally going your way!

I hope things is going well for you too!

[GenChick (imported)]

I see that things progressing for you. Very good!

I also, just today, was referred to see a physiologist. :redbounce

Uuups! I meant psychologist.

[Frida G Cavic (imported)]

I only write a follow up to this thread because I want to help with my experience to others with prolactinoma, because there are very poor information in regards to real and trustful information about cases of prolactinoma.

my last test of prolactin went normal. currently i+m taking cabergolin and I´m doing it well, also i'´m injecting perlutal and I feel good.

thanks.

WARNING: taking hormones is a risk, and prolactin seems to be an item often forgotten when ones is on an hormonal regimen whatever that were. Estrogen estimulates the lactotrophes cells in pituitary but this stimulatoin is highly increased when is combinated with progestagens. progestagens alone also seems to increase prolactin a very high levels of prolactin can be an early sign of a develpoment of prolactinomas wich ma cause very nasty issues.

PD Ich suche einen Deutschlehrer

[Mareenah (imported)]

Thank you for the update on your progress in solving the prolactinoma issue, freddyde! I know how difficult it was to you.

About an year ago, I was afraid of possibly having developed prolactinoma. After going to my first routine blood work including PRL I go a result showing 213µg/L which is just 10 times above the norm. I instantly freaked out. I was self medicating (I'm still on DIY HRT) and didn't liked the prospect of interrupting my transition. I was on 4 mg of Estradiol hemihydrate SL and 50 mg of CPA. I was on CPA for about 3 months, but learned that it was able to increase prolactin levels and eventually induce pituitary tumors. I stopped CPA right away and went for a MRI scan of my pituitary paying just a bit over $200 (incl. contrast material) out of my pocket. The analysis showed no prolactinoma (thankfully). The contrast image was made just 4 days after me discontinuing CPA and I did a second blood work on PRL which showed that my prolactin had dropped to 48µg/L which was bringing it to light that it was in fact Androcur which elevated my PRL tenfold. I'm on Spiro as an anti-androgen since then and had just recently increased my Estradiol dosage to 6mg/day SL. I'm thankful that I found your topic and other information online which made me reconsider and stop using CPA.

[Frida G Cavic (imported)]

One and a half year since my prolactinoma was detected. I´m now in carbegolin and everything is ok, my results of prolactine were into the normal range and the best of all is that I´m stil injecting estradiol but my prolactin is under control.

[Mareenah (imported)]

How are your T levels now that your prolactin is no longer suppressing LH? You told a while ago that they were previously undetectable, pre-diagnosis.

[Begoneboy (imported)]

Mareena,

If you're pre surgery try adding estriol cream to your daily treatment rather than increasing estradiol.

The receptors for the two different estrogens act in different ways on your body.

You'll see subtle results in about 10 days far easier on your pocketbook. And if you are taking the estradiol orally

you may consider rectally to increase the results without increasing the dose. The documented difference

of HRT rectally verses orally is a remarkable increase in your estrogen levels either by the saliva or blood test.

And you'll "FEEL" the difference while others will actually see the subtle differences..

Coming from a couple decades of practical experience. HI Hi!

[Frida G Cavic (imported)]

How are your T levels now that your prolactin is no longer suppressing LH? You told a while ago that they were previously undetectable, pre-diagnosis.

june 6 2017. testosterone= 6 ng/dL. extremely low. I just want to remark that I do not use antiandrogens because I´ve damaged my testicles with cacl2. I ´m only on estradiol and dihydroxyprogesterone one shot every two weeks

[Prismatic (imported)]

you may consider rectally to increase the results without increasing the dose. The documented difference

of HRT rectally verses orally is a remarkable increase in your estrogen levels either by the saliva or blood test.

And you'll "FEEL" the difference while others will actually see the subtle differences..

Coming from a couple decades of practical experience. HI Hi!

Would you be willing/able to share any documented evidence of rectal estradiol administration being more effective, or simply just working? I'm interested in reading into it.

Would such an administration route work with oral estradiol valerate e.g. progynova?

[Begoneboy (imported)]

Would you be willing/able to share any documented evidence of rectal estradiol administration being more effective, or simply just working? I'm interested in reading into it.

Would such an administration route work with oral estradiol valerate e.g. progynova?

I don't have the pages (multiple from doctors) at the moment but this form of administration is extremely well documented. The OBgyn at our free clinic indeed prescribes this rout to women who suffer vaginal dryness since it cost about 4 cents a day with 1mg estradiol oral pills inserted rectally in place of the more expensive (4.00 dollars a day estrogen vaginal cream). It is well documented that rectal administration provides the exact same results as vaginal administration. Google "hormones taken rectally" and you will find an extreme amount of documentation.

In my case this is the exact way I take my estrogen and the results are infinitely more noticeable than oral administration principally due to the fact that the medicine is not being broken down by stomach acids via oral administration.