Spiro, Dutasteride and Cyproterone Acetate Combination

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shadow1ninja (imported)
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Spiro, Dutasteride and Cyproterone Acetate Combination

Post by shadow1ninja (imported) »

I am taking combination of these medications for the purpose of stopping hair loss as well as thickening existing hair (i have slightly thin hair ) when its long it looks thick however at the moment its cut short and the thin areas show more, and I am taking this combination for the purpose of chemical castration. Also, There are clinical studies showing even at 12mg Cyproterone Acetate drastically lowered sperm count even while on hrt.

My routine is

Dut 0.5mg daily ( 7days a week)

Spiro 6mg daily (mon to fri)

Cyproterone Acetate (tue & thurs 12.5mg, fri 25mg, sun 50mg)

I am wondering if I should add-in Depo-Provera into my routine ?>

Should I up the dosage/frequency of Cyproterone Acetate ? and this medication does have 40 hour half life

So far my desires are lower, i do not think of sexual thoughts, my pen*s is limp, more sensitive, smaller, balls seem to shrunk a little bit

feeling a nice sense of freedom from the desires of wanting a female which is excellent.. I am 23 years old and a University student at the

moment, I still am aware of girls i like, but do not feel horny or urges however there is a sense of nervousness around girls and awareness sometimes.

I still have the desire to form a friendship with a female for example there was 1 girl i met who started talking to me, she seemed interested to chat

she was asking me personal questions, i felt insecure, anxiety and said 'see you later i got class now' and went to class. This happened about three times

on three different Mondays. I am hoping to break that barrier and chat to her on Monday to be her friend because I haven't had a female friend before and always felt

isolated, alone and never properly chatted to females in my age group.

http://www.unboundmedicine.com/medline/ ... te_as_a_ma le_contraceptive_

http://www.unboundmedicine.com/medline/ ... osterone_e nanthate_for_contraception_in_men_

http://www.ncbi.nlm.nih.gov/pubmed/9647551

http://www.unboundmedicine.com/medline/ ... ffects_on_ hormone_secretion_and_on_spermatogenesis_in_men_

cypro acetate -Pharmacokinetic data

Bioavailability 100%

Protein binding 96%

Metabolism hepatic

Half-life about 40 hours

Excretion 60% bile, 33% renal

source - http://en.wikipedia.org/wiki/Cyproterone_acetate

Anyway, thanks for reading my questions and my brief personal experience, I would appreciate your comments on this thread.
cheetaking243 (imported)
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Re: Spiro, Dutasteride and Cyproterone Acetate Combination

Post by cheetaking243 (imported) »

Not sure why you'd need THREE different anti-androgens...

Seriously, Spiro, Androcur, and Depo all do exactly the same thing. Taking that much would be overkill.

100 mg of Androcur a day alone was more than enough to knock my T levels down to castrate levels in only 2 months or so. Androcur is way more effective than Spiro. Spiro, I've had transgender friends who took as much of 200 mg a day of it, and it still took almost a whole year to get their T levels down far enough. Androcur should easily knock it down all by itself. Depo would be the last resort, if for some reason Androcur doesn't work. (Which for most people it should, more than enough.)
Riverwind (imported)
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Re: Spiro, Dutasteride and Cyproterone Acetate Combination

Post by Riverwind (imported) »

I agree, from the sound of it your self medicating that is not a good idea, I know I did it myself with Androcur and it does work in a short time. I would recommend that you see a doctor and get some blood work done. You don't want to be screwing up your liver for life by taking three different drugs when one would do and not be harmful.

River
shadow1ninja (imported)
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Re: Spiro, Dutasteride and Cyproterone Acetate Combination

Post by shadow1ninja (imported) »

Yes, I will get a Doctors appointment booked for some point in the next week to check blood work and see if everything is fine.. I have previously used Cypro and Dut last year as well and haven't took a break from it, lucky it has not had any bad effects on me, my fitness is good, strength is fine and the main effect it had was lowering my desires. And I feel more emotional, more sensitive than usual and my aggression is almost non-existent.
Jorge2008 (imported)
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Re: Spiro, Dutasteride and Cyproterone Acetate Combination

Post by Jorge2008 (imported) »

I was on Spiro a year and a half ago, it did absolutely nothing to me. Consider that Spiro is a rather weak androgen: it does not add anything to Androcur, if you're taking it anyway, and on the other hand Spiro can mess up with electrolytes (it's actually a potassium sparing diuretic). So I'd suggest you stick to Androcur. Also, if you're considering Provera, then the positive side is that there's less of a chance getting gynecomasty with Depo Provera compared with Androcur.
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