My Intro: Seeking surgical castration for medical reasons(POIS & Hypersexuality)

[Legionnaire (imported)]

I am a straight 24 yr old male who identifies as male. I've done my research and I believe I am just as worthy of surgical castration as anyone. My reasons are legitimate, logical, and well thought out.

I've suffered from a severe, disabling, case of Post Orgasmic Illness Syndrome(POIS) for ~6 years and masturbation addiction/hypersexuality for ~11 years. These combined conditions, along with lifelong social anxiety disorder, have made employment impossible for me and have deprived me of every activity I used to enjoy. Every time I orgasm/ejaculate I experience symptoms including burning eyes, face irritation, back pain, joint pain, exhaustion, anxiety, cognitive impairment, increased pain sensitivity, perhaps depression, pain during urination & bowel movements, and more. Due to my masturbation addiction/hypersexuality I am forced to masturbate to orgasm 3-7 times every single day. I've tried everything from straight willpower to supplements/meditation to antidepressants to reduce my libido and it has all failed. The antidepressants caused permanent hair loss and knee pain, which caused me to completely swear off of synthetic drugs. I will not risk side effects from synthetic drugs.

The only thing that has helped me control my libido is a chastity device I designed and constructed that prevents erections via pain. The device has two nails placed against both sides of my penis so that when I become erect the nails will drive into my penis. I've been wearing this device for more than a year now during times I need to be functioning at my best and it has enabled me to cut back my ejaculations to 1-3 times per night(nocturnal erections prevent wearing it during sleep). This way I am able to sleep through the worst part of my symptoms. Attempts to design a device that would be wearable during sleep have failed and I have no money to try buying a professionally designed chastity device.

If my willpower fails and I have an unplanned ejaculation in the morning(which happens at least once a week) I will be wracked with pain, exhaustion, and cognitive impairment that leaves me completely bed-ridden for the entire day. After each ejac I am nearly unable to walk due to knee/hip pain, unable to sit due to back pain, and my thought speed, capacity, and memory are decreased to a near vegetative state. These and the immediate onset of intense fatigue force me to lay motionless in my bed for at least an hour after every ejac. Within 3 hours I am able to walk/sit/think at perhaps the level of an 80 year old woman with crippling chronic pain/fatigue/dementia.

I've tried many supplements which I learned about at the pois forums(I've read virtually every post there) in an attempt to improve my symptoms and some have been quite helpful, but it's not enough to get me to a point where I could even work part-time. There is no other drug or treatment available to me that is as likely to help my symptoms as much as castration would. There has only been one scientific study done on pois so far and there will likely not be a treatment developed in time to help me before the damage caused by pois to my body has become permanently disabling.

I have no money or transportation so doctors are out of the question. I am not willing to try any more synthetic drugs so chemical castration is definitely out of the question - besides chemical castration wouldn't cause the same effects real castration would anyway so it wouldn't be a reasonable trial. POIS is not known by 99% of doctors so a doctor would just brush me aside to a psych(which I've already found to be a fruitless path for me) so even if I did have the funds and transportation to see a doctor it would likely take years before I was approved for an orchiectomy. I don't have years; if my symptoms worsen at the rate they have been I estimate that within 5-10 years I will have permanently lost the ability to walk and sit due to knee and back pain. The worst case scenario would be that a doc would consider me to be at a danger of self harm and have me committed to a mental hospital and there's no way I'm going to allow that on my record.

I have read extensively about the side effects of castration: breast enlargement, physical weakness, hot flashes, depression, bone weakness, fatigue, penile shrinkage, cognitive decline, etc. All of this honestly sounds like a walk in the park compared to the pain I've been through. I've dealt with suicidal depression at such regularity that I have come to believe it is something most people deal with, but this kind of emotional pain is nothing compared to the disabling physical pain I go through daily. There was one member at the pois forums who's symptoms improved after castration. After weighing all the data I've determined I'm much more likely to be healthier post-castration. I've also read several anecdotal experiences of eunuchs and overall I believe it is most likely going to be a favorable outcome for me; and if I get more disabling symptoms I've lost nothing anyway since I have nothing to lose.

Because of POIS and hypersexuality I have lost my friends, education, hobbies, sense of purpose, job/ability to work, relationships, and more. Tried college and was forced to drop out because I couldn't even tolerate sitting in the chairs in class due to back pain. Tried working at a gas station and my boss constantly got on my case since I didn't have the mental ability/energy to keep up and eventually I was forced to quit due to back pain. During the time at this job I was also on a heavy CNS depressant drug(klonopin 3mg) that significantly decreased my pain/anxiety and even with that I wasn't able to bare the pain or function. A lot of the time I don't have the energy to even put on my device so many of my days consist of nothing but alternating masturbation/pain/sleep. (~15 min masturbation session + ~1 hour bed rest) x (3 to 7) = Not much time left for anything else. This is a life or death situation for me. Actually I barely consider myself alive at this point. If I do not achieve eunuch status I will go homeless and die on the streets once my family is no longer able to care for me. Also POIS is causing permanent damage to my body and brain each day and each year I feel weaker, less intelligent, and more tired. Surgical castration is literally my only chance for survival. This post took me about 3 hours to write - that's the kind of cognitive impairment I'm talking about.

[foxytaur (imported)]

Ive heard of rare individuals falling extremely ill from ejaculatory fluid much like a strong case of allergy.

I saw this on TV a few yrs back. A certain dude was allergic to his own semen. They performed castration on the poor guy.

For even injecting microscopic doses of his very own semen back into his bloodstream couldn't alleviate his heavy flu like symptoms.

Is this the POIS your reffering to Legionaire?

I don't know much about POIS but it seems fascinating, much like how peanuts severely affect people allergic to them.

[Legionnaire (imported)]

Is this the POIS your reffering to Legionaire?

Sort of. In the only scientific study done on POIS the cause was hypothesized to be an allergy/autoimmune response to the body's own semen, but that is far from confirmed. I've actually conversed with the man you saw on television at the POIS forum on several occasions and he is the one I mentioned in my above post who had improved POIS symptoms post-castration. He also needed to have surgery done to stop all semen production in his body before he experienced complete relief from POIS, but as of now those surgeries are completely unavailable to me while castration may be within my grasp. While castration may directly counteract the main mechanism behind the cause of my POIS symptoms I mainly am seeking it to decrease my libido since even just that would be an enormous relief to me.

There are several hundred other POIS sufferers known on the pois forums, but I've read of few cases as disabling as mine.

Also I just remembered one difference between me and the man you saw on tv. His POIS was initially caused by a sex enhancement herbal supplement he used whereas mine slowly developed after I first began having orgasms/ejaculations.

[raymar2020 (imported)]

Your story is most distressing. To have such a condition must be really tough. I would suggest that you seek out what sort of medical assistance is available where you live. Here in Baltimore, even those that fall thru the cracks for Medicaid can get care thru several privately funded clinical programs. They also employ younger and therefore more open minded physicans.

I know an HIV patient here that developed terrible testicle pain. The drug cocktail he is using produced that side effect. His physican at one of those clinics arranged for him to be castrated, and his pain has stopped. He uses HRT to replace the lost testosterone, and is doing well.

If you apply the diligence to a search for medical help that you have to your research, I am sur you can find assistance.

I am also told that POIS can be cured by removal of the testicles and prostate. Eliminating the sources of any semen, as well as most sexual desire seem to work.

Good luck on your quest.

[Legionnaire (imported)]

I would suggest that you seek out what sort of medical assistance is available where you live. Here in Baltimore, even those that fall thru the cracks for Medicaid can get care thru several privately funded clinical programs. They also employ younger and therefore more open minded physicans.

Thanks for your response. I have thought a lot about medical assistance options, but with limited funds/transportation even the $15 copay is a real wall for me. If I tell a doctor about my POIS that closes the door for other options, such as the alcohol injection method since if I go in with dead testes he'll know immediately what I've done. I don't have enough money, energy, confidence, time to go through this process with multiple doctors.

Right now my choice is I can either spend my money on doctors who most likely will just refer me to psychs or I can spend my money on equipment to take matters into my own hands. Don't have enough money for both. I've got roughly $200 to spend on this and zero income. All of my family's income goes to bills/college loans and we can barely pay for food so asking them for money is not possible.

Even just convincing a doctor that my POIS is a real disease and is actually disabling to me would probably take at least 3 separate visits or $45. The chance he would even consider castration is highly unlikely. It's simply not a smart route for me to go.

I understand that if I make a mistake and need a hospital visit the bill will be in the thousands and thousands of dollars. That will not happen as I plan to read virtually every post here on every method and then weigh my options before deciding on what to do.

[JesusA (imported)]

A search of PubMed and a consultation with my favorite professor of urology turned up the most logical person to whom to write about POIS. Dr. Marcel Waldinger in the Netherlands is apparently the world's expert on the syndrome. Below are the abstracts from three articles that he has published on the subject.

I suggest that you send an email to Dr. Waldinger asking for PDF copies of these three articles and asking if he knows of anyone in your area who would be willing to work with you. There should be a research hospital where someone would be very happy to study your case (and provide free treatment in exchange). I would suggest that, rather than including it as part of a long email, you keep your email brief and attach either the description that you posted to begin this thread or a similar detailed description as a Microsoft Word document.

Waldinger and his colleagues have apparently been able to successfully treat patients with POIS, though it is a long and slow process. Your willingness to consider castration for treatment may get your priority as a research subject (AKA "lab rat").

Good luck!

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Postorgasmic illness syndrome: two cases.

Waldinger MD (http://www.ncbi.nlm.nih.gov/pubmed?term ... d=11995603), Schweitzer DH (http://www.ncbi.nlm.nih.gov/pubmed?term ... d=11995603).

Department of Psychiatry and Neurosexology, Leyenburg Hospital, Leyweg 275, 2545 CH The Hague, The Netherlands.

md@waldinger.demon.nl

Abstract

We describe the symptoms of a postejaculatory syndrome in two men with spontaneous ejaculations. The syndrome consists of severe fatigue, intense warmth, and a flulike state, with generalized myalgia. These symptoms occur rapidly after ejaculation and only disappear after 4 to 7 days. The symptoms are so severe that sexual activity is avoided. The cluster of symptoms is named postorgasmic illness syndrome (POIS). To date, no explanation has been offered for the etiology and pathogenesis of the symptoms, and the prevalence is unknown. Both cases are presented to draw attention to this syndrome for further research regarding etiology, pathogenesis, and treatment.

Journal of Sex & Marital Therapy. (2002), 28:251-5.

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Postorgasmic Illness Syndrome (POIS) in 45 Dutch caucasian males: clinical characteristics and evidence for an immunogenic pathogenesis (Part 1).

Waldinger MD (http://www.ncbi.nlm.nih.gov/pubmed?term ... d=21241453), Meinardi MM (http://www.ncbi.nlm.nih.gov/pubmed?term ... d=21241453), Zwinderman AH (http://www.ncbi.nlm.nih.gov/pubmed?term ... d=21241453), Schweitzer DH (http://www.ncbi.nlm.nih.gov/pubmed?term ... d=21241453).

Abstract

INTRODUCTION:

Postorgasmic illness syndrome (POIS) is a combination of local allergic symptoms and transient flu-like illness. In this study, the investigators propose five preliminary criteria to establish the diagnosis.

AIM:

To describe the clinical details in 45 males being suspected of having POIS and to test an immunogenic hypothesis as the underlying mechanism of their presentations.

METHODS:

Forty-five males were studied according to standardized protocol, including neuropsychiatric and medical sexological evaluations; their complaints were categorized using their own words, and their self-perceived intravaginal ejaculation latency time (IELT). Skin-prick testing with autologous diluted semen in 33 men were also performed.

MAIN OUTCOME MEASURES:

Clinical features of POIS including self-perceived IELTs and the results of skin-prick testing with autologous diluted seminal fluid.

RESULTS:

Of the 45 included men, 33 subjects consented with skin-prick testing. Of them, 29 (88%) men had a positive skin-prick test with their own (autologous) semen, and four had a negative test. In 87% of men, POIS symptoms started within 30 minutes after ejaculation. Complaints of POIS were categorized in seven clusters of symptoms, e.g., general, flu-like, head, eyes, nose, throat, and muscles. Local allergic reactions of eyes and nose were reported in 44% and 33% of subjects, a flu-like syndrome in 78% of subjects, exhaustion and concentration difficulties in 80% and 87% of subjects. Of all subjects, 58% had an atopic constitution. Lifelong premature ejaculation, defined as self-perceived IELT < 1 minute, was reported in 25 (56%) of subjects.

CONCLUSIONS:

The combination of allergic and systemic flu-like reactions post-ejaculation together with a positive skin-prick test in the majority of males underscores the hypothesis of an "immunogenic" etiology of POIS, e.g., that POIS is caused by Type-1 and Type-IV allergy to the males' own semen, as soon it is triggered by ejaculation.

Journal of Sexual Medicine (2011). 8: 1164-70. doi: 10.1111/j.1743-6109.2010.02166.x.

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Hyposensitization therapy with autologous semen in two Dutch caucasian males: beneficial effects in Postorgasmic Illness Syndrome (POIS; Part 2).

Waldinger MD (http://www.ncbi.nlm.nih.gov/pubmed?term ... d=21241454), Meinardi MM (http://www.ncbi.nlm.nih.gov/pubmed?term ... d=21241454), Schweitzer DH (http://www.ncbi.nlm.nih.gov/pubmed?term ... d=21241454).

Source

Department of Psychiatry and Neurosexology, HagaHospital, The Hague, The Netherlands.

md@waldinger.demon.nl

Abstract

INTRODUCTION:

Postorgasmic illness syndrome (POIS) is a post-ejaculatory complex of local and/or systemic symptoms that nearly always occurs within seconds, minutes, or hours post-masturbation, coitus, or spontaneous ejaculation. Recent data suggest an autoimmunogenic/allergic underlying mechanism.

AIM:

To treat males with POIS by hyposensitization with their own semen (autologous semen).

METHODS:

Two males suffering from POIS, of which one male with coincidental lifelong premature ejaculation (PE) were investigated. Based on their local and systemic symptoms including a positive dermatologic reaction after skin-prick testing with autologous semen, auto-allergy to semen was likely an underlying mechanism. A hyposensitization program was initiated, including multiple subcutaneous (SC) injections with autologous semen, initially at 2 weeks intervals in the first year and gradually at 4 weeks intervals in the second and third year. From initial semen dilutions of 1 on 40,000 and 1 on 20,000, the titers were gradually increased to 1 on 20 and 1 to 280, respectively.

MAIN OUTCOME MEASURES:

Evaluation with a dedicated questionnaire about severity of POIS symptoms and specialized interviews on self-perceived intravaginal ejaculation latency times (IELT) before and during the desensitization program.

RESULTS:

POIS was confirmed in both subjects, PE was confirmed in one male, and skin-prick tests with autologous semen in both subjects were positive. During the program, gradual reduction of complaints resulted in 60% and 90% amelioration of POIS complaints at 31 and 15 months, respectively, which coincided in one male with a delay of the IELT from 20 seconds at baseline to 10 minutes after 3 years of treatment. The cause of this association with IELT is unknown and remains to be elucidated.

CONCLUSIONS:

Two males with POIS were successfully treated by hyposensitization with autologous semen, which supports an immunogenic/allergic etiology and underscores the clinical implication for immunological sexual medicine.

Journal of Sexual Medicine. (2011). 8: 1171-6. doi: 10.1111/j.1743-6109.2010.02167.x.

[Legionnaire (imported)]

my computer died so im seeing if my ps3 will work to post here

[Legionnaire (imported)]

Jesus, thank you for your response. The POIS forums have been in occasional contact with Dr. Waldinger, but he is very busy. I do have the research articles already. It's just that based on experiences fellow forum members have had it doesn't seem likely that even a doctor knowledgable about POIS would see me as a candidate for an orchiectomy. I'm aware of the other treatments that have been tried on POIS sufferers, but I don't feel those treatments would be appropriate for my case due to my hyperactive libido and my sensitivity to chems. Also there is no way for me to travel for regular visits for immunotherapy and I doubt anyone would arrange free travel for me as even Dr. Waldinger is struggling to obtain research funding for POIS. It was a good suggestion though, perhaps I will try sending Mr. Waldinger an email, but I seriously doubt he'd know any doctors in my area.

[nullorchis (imported)]

assumptions and doubt are your nemesis. '

For all of us, nothing but hurdles, road blocks, and open pits lie ahead.

Persistence is paramount.

Giving up is not an option.

You are your own best advocate.

Best wishes.