SplitDik (imported) wrote: Sat Jun 27, 2015 8:00 am
As I am the main "instigator" of these methods (I started this thread, as well as the lactic acid thread years ago), I based all my suggestions on veterinary studies. As far as I know there are only six chemicals that seem to have some effect while also being relatively safe:
1) Zinc Gluconate (Zeuterin). This actually is more of a sterilant and less of castration chemical. Generally it is known that zinc in the testicles will greatly reduce funcion. This acts based on the presence of the zinc and isn't primarily about causing damage.
2) Calcium Chloride. This is growing in popularity for veterinary purposes. It is highly dose dependent though, and longer term studies show that it needs to be mixed with high-proof ethanol otherwise function can return after a year. CaCl's action is desirable because it doesn't do much immediate tissue damage but rather prevents the normal regeneration of cells so they simply atrophy over time.
3) Super-tonic Sodicum Chloride. Basically this is just salt water with highest concentration of salt as possible. It works by causing immediate cell damage.
4) Gycerol. Basically this causes damage simply by creating pressure with high infusion.
5) Lactic acid. Basically this directly destroys the tissue.
6) High-proof ethanol. Basically this directly destroys the tissue. But it wasn't deemed effective for veterinary purpose because it usually requires many multiple injections.
All of the above can be used successfully. They are mostly unsafe when dosages are wrong. For example, there was a person who had a lot of trouble with lactic acid (basically the acid ate through his scrotum and into his pelvis, causing infection and multiple reparative operations) actually way overdosed it -- he was impatient and did three times the recommended volume.
I personally would not use any of the methods that create their effect through immediate tissue damage, as then the concerns about the chemical traveling outside the testicle become serious. I personally don't like just ethanol because there are so many people who have injected dozens of times without fully achieving castration; however, it is likely the safest (just make sure to only use ethanol and not other types of rubbing alcohol as they can kill you and make you blind). I think CaCl mixed with ethanol is the best because it is a one-time shot (if dosed correctly) that is proven to be consistently effective and further is fairly safe due to its slow action; however, unfortunately it is much more painful that the veterinary literature claims -- you can count on three days of extreme discomfort.
Anyway, please don't go making up new methods. There are plenty of options already studied for veterinary purposes, and you really don't know how bad certain chemicals can be. Don't risk your life or overall health for castration!