T levels 12 months after Depo Provera

[innocent_in_574 (imported)]

Three year ago I had my T level checked and it was around 500 (not sure the units). Since then I have used Depo Provera twice for six months each time. The first time I started with 300mg then followed with 150mg monthly. The second time I started with 300mg and followed that with 150mg bi-weekly. My reason for doing this is because I am totally impotent due to a neurological medical condition. Erections are nearly impossible and orgasms are extremely difficult to achieve. I know that some enjoy penectomy stories where the man is kept horny forever, but the reality if it is not so erotic. It's torture. And very taxing on a marriage.

I had my T levels checked recently and to my astonishment the level was over 700 (again, not sure the units). I expected, and was hoping, that my levels would have been lowered by my use of Depo Provera.

I am faced with a future of a high sex drive and no way to get relief. My wife likes it when I am chemically castrated because I am much happier, but I know she misses sex. She doesn't complain though. I have been thinking about a penis implant. Does anyone have experience with these? It would be nice to be able to have sex with my wife, even if I cannot orgasm.

Any thoughts???

[daledale (imported)]

Some people need levels of 400-800 per week for chemical castration, acccording to Medical schools site. 150 biweekly will not do it. Try adding Siterone.

I take 450 biweekly and 25mg daily, be doing this for years. T level varies between 20-35

[neutrois (imported)]

I'm curious why people use Depo-Provera and not Goserelin (aka Zoladex)? http://en.wikipedia.org/wiki/Goserelin

Depo-Provera's intended as a contraceptive, is hormone-based and known to have a lot of negative side effects while not always being effective. Goserelin's designed specifically to suppress sex hormone production and tends to be extremely effective.

After a couple of months on Goserelin I was testing at near zero for testosterone. It's administered as a monthly or three monthly implant into stomach fat below the naval. The only downside is that for your first injection only you get very high 'flare' T levels for the first week or two as your endocrine system adjusts. You can take another blocker as well during that time. I took Androcur as well for the first couple of weeks.

My most recent blood test while on Goserelin was 0.8 nmol/L testosterone level.

I'm not sure about costs, I'm funded by the UK National Health Service.

[fhunter]

I'm curious why people use Depo-Provera and not Goserelin (aka Zoladex)? http://en.wikipedia.org/wiki/Goserelin

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I'm not sure about costs, I'm funded by the UK National Health Service.

Probably costs - 1ml depo provera (once per month if I remember correctly) ~5$ here.

Zoladex - 1 dose?? (3.6mg) (monthly if I have read the information correctly) - ~250-300$.

It is the question of price and availability. Plus, depo provera is a contraceptive, so it is more or less readily available without extra questions.

PS. Prices are local to me, in UK/USA they may be different.

[neutrois (imported)]

Probably costs - 1ml depo provera (once per month if I remember correctly) ~5$ here.

Zoladex - 1 dose?? (3.6mg) (monthly if I have read the information correctly) - ~250-300$.

It is the question of price and availability. Plus, depo provera is a contraceptive, so it is more or less readily available without extra questions.

PS. Prices are local to me, in UK/USA they may be different.

Ah yes, that makes sense. It seems I'm getting my tax money's worth out of the NHS! My gender clinic actually prescribes Goserelin to all MtF patients as standard, so getting it as a MtN already on Androcur didn't turn out to be a problem.

[innocent_in_574 (imported)]

I guess the reasons I decided on Depo Provera are cost and availability. I tried androcur a while ago, and it worked amazingly well, but it is not FDA approved in the US and therefore a little harder to get. Not to mention it's much harder on the liver.

Daledale, can you post the like to the medical school article that talks about using 400 - 800mg a week?

I still have concerns about sex for my wife. My neurological illness all but eliminates my ability to orgasm, whether taking depo or not. I have been considering a penis implant and want to learn more about them. Is there anyone here that has any knowledge of these implants? Any help is appreciated.

[SplitDik (imported)]

I guess the reasons I decided on Depo Provera are cost and availability. I tried androcur a while ago, and it worked amazingly well, but it is not FDA approved in the US and therefore a little harder to get. Not to mention it's much harder on the liver.

Daledale, can you post the like to the medical school article that talks about using 400 - 800mg a week?

I still have concerns about sex for my wife. My neurological illness all but eliminates my ability to orgasm, whether taking depo or not. I have been considering a penis implant and want to learn more about them. Is there anyone here that has any knowledge of these implants? Any help is appreciated.

Depo Provera isn't a direct castration drug. It can have a secondary effect on lowering T, but can also raise it, etc. It is really a precursor to both estrogen and testosterone, and can help create both. But for some reason if you take enough your body thinks you already have enough T and surpresses it. Anyway, this is very different than other drugs which directly block the production or receptors for T.

For castrate levels for some guys, I think you need at least 200mg per week. The dosing is often only listed for women for contraceptive purposes, and for that it apparently has a half-life of over a month (i.e. only needs to be injected every few months to stay effective), but for men it has half-life of only a couple days. Also, many of the "men" who use it are actually MtF who also take estrogen, which creates yet another complex interplay with testosterone production.

Regarding your sex life with your wife, I know regular intercourse is great, but frankly I've found very few women who like intercourse as their primary way to get off. Usually there is lots of manual or oral stimulation, and maybe finishing with a vibrator. You can also just wear a strap-on to simulate the intercourse (for her).

Regarding your inability to orgasm, you should try anal electro stimulation. Although that may not be overly appealing to a straight guy (I don't really like it), the right electro-stim can force ejaculation even when your dick is limp. There are even electro-ejaculators (some medical grade and prescribed) which basically shock the ejaculation muscles and force an ejaculation. This is similar to what they use on livestock.

[innocent_in_574 (imported)]

Split, thanks for the info. I have been looking into the electro ejaculation thing. It's very appealing, but expentive. You said there are medical grade stimulators available. Do you have any specific information you can share or can you point me in the right direction? Who knows, maybe my health insurance would pay for it...