Saline injection as alternative to Orcjiectomy?

[snakecharmer (imported)]

I ran across this article and thought back to the alcohol injection thread. This is most curious. Does anyone have more information on this? While humans are not rats, most anyway, I wonder how this would apply to men?

taken from:

http://www.urotoday.com/61/browse_categ ... emoablatio n_of_testes_with_hypertonic_saline_solution_as_a_t reatment_method_alternative_to_orchiectomy_in_pati ents_with_hormone_sensitive_metastatic_prostatic_c ancer__abstract.h

Hormonal and Pathologic Changes after Chemoablation of Testes with Hypertonic Saline Solution as a Treatment Method Alternative to Orchiectomy in Patients with Hormone Sensitive Metastatic Prostatic Cancer - Abstract Show Comments PDF Print E-mail

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Monday, 06 April 2009

Ministry of Health, Ankara Training and Research Hospital, 1st Clinic of Urology, Ankara, Turkey.

We tried to clarify whether less invasive and lower-cost method of injecting hypertonic saline solution could be an alternative to orchiectomy.

Thirty adult healthy male Wistar rats were used as experimental animals. Three groups were made as 0.9% NaCl administered to the first group, orchiectomy performed to the second group, and 20% saline solution administered to the third group. To measure baseline testosterone values were obtained from all rats 1 day before the procedure. Blood samples obtained to analyze total testosterone from all rats at days 1, 15, and 60 were centrifuged and stored in deep freeze. After blood samples were obtained at day 60, intramuscular 100 IU HCG (Pregnyl) was administered to all rats. Following HCG injection, new blood samples were obtained to analyze testosterone levels at 120 minutes.

On microscopic examination, while extensive coagulation necrosis was seen in the third group, in only two samples in this group, an area of intact tissue was observed. Baseline, day 1, day 15, and month 2 testoterone levels of all groups were analyzed. When changes in testosterone levels between baseline values and month 2 control levels were compared, changes in the second and third group were detected statistically significant, and there was no statistically significant difference between these two groups. When month 2 and post-HCG stimulation test serum testosterone levels were compared, a statistically significant increase was found only in the first group.

These data indicate that since there are nearly the same pathological and biochemical results with bilateral orchiectomy and no negative findings were found for comorbidity, bilateral injection of 20% hypertonic saline solution into the testes could be an alternative in the treatment of hormone-sensitive metastatic prostate cancer.

Written by:

Emir L, Sunay M, Yalbuzdag O, Karakaya Y, Erol D. Are you the author?

Reference:

Urol Oncol. 2009 Mar 7. Epub ahead of print.

doi:10.1016/j.urolonc.2008.12.021

[_g (imported)]

Hypertonic Saline Solution is not normal saline solution, and it kills the cells by too much salt. This would be the same as ethanol alcohol injection. But how many injections which would be required is unknown.

[SplitDik (imported)]

Note I had a long time ago posted a veterinary patent relating to using calcium chloride (a salt) for castration of cows.

Yeah, it probably works, but it has to be a high concentration of salt and we don't know how safe or painful it would be.

[asphalt-cowboy (imported)]

Yeah, it probably works, but it has to be a high concentration of salt and we don't know how safe or painful it would be.

So someone should try that, to find out (just kidding)

[mrt (imported)]

I know I sound like an old mother hen but PLEASE do not be pioneers in this. One of our posters that I was friends with tried a "do it yourself" castration. *And he was a medical student so you might expect he had some more knowledge then the usual nit wit. While he lived through the initial attempt (Thanks to EMTs and the ER) he died after they released him from the pych ward when they tried to fix the mess he made in surgery.

Talk to some doctors and first find out why you want to do this.

If you really need this find a REAL doctor to help you. No syringes filled with ______, clamps or animal castration wrenches.

[micropenis (imported)]

Asphalt-cowboy???

Try a padded sadle.